Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Bitter Ordeal

Search target player's library for a card and exile it. Then that player shuffles.
Gravestorm (When you cast this spell, copy it for each permanent put into a graveyard this turn. You may choose new targets for the copies.)

Surgical Extraction

({B/P} can be paid with either {B} or 2 life.)
Choose target card in a graveyard other than a basic land card. Search its owner's graveyard, hand, and library for any number of cards with the same name as that card and exile them. Then that player shuffles.

Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Sadistic Sacrament

Kicker {7} (You may pay an additional {7} as you cast this spell.)
Search target player's library for up to three cards, exile them, then that player shuffles. If this spell was kicked, instead search that player's library for up to fifteen cards, exile them, then that player shuffles.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Ashiok, Nightmare Muse

+1: Create a 2/3 blue and black Nightmare creature token with "Whenever this creature attacks or blocks, each opponent exiles the top two cards of their library."
−3: Return target nonland permanent to its owner's hand, then that player exiles a card from their hand.
−7: You may cast up to three spells from among face-up cards your opponents own from exile without paying their mana costs.

Cranial Extraction

Choose a nonland card name. Search target player's graveyard, hand, and library for all cards with that name and exile them. Then that player shuffles.

Etherium Sculptor

Artifact spells you cast cost {1} less to cast.

Thassa's Oracle

When Thassa's Oracle enters the battlefield, look at the top X cards of your library, where X is your devotion to blue. Put up to one of them on top of your library and the rest on the bottom of your library in a random order. If X is greater than or equal to the number of cards in your library, you win the game. (Each {U} in the mana costs of permanents you control counts toward your devotion to blue.)

Mystic Forge

You may look at the top card of your library any time.
You may cast artifact spells and colorless spells from the top of your library.
{T}, Pay 1 life: Exile the top card of your library.

Jester's Cap

{2}, {T}, Sacrifice Jester's Cap: Search target player's library for three cards and exile them. Then that player shuffles.

Circu, Dimir Lobotomist

Whenever you cast a blue spell, exile the top card of target player's library.
Whenever you cast a black spell, exile the top card of target player's library.
Your opponents can't cast spells with the same name as a card exiled with Circu, Dimir Lobotomist.

Extract

Search target player's library for a card and exile it. Then that player shuffles.

Nightmare Incursion

Search target player's library for up to X cards, where X is the number of Swamps you control, and exile them. Then that player shuffles.