Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Suffer the Past

Exile X target cards from target player's graveyard. For each card exiled this way, that player loses 1 life and you gain 1 life.

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Radiant Fountain

When Radiant Fountain enters the battlefield, you gain 2 life.
{T}: Add {C}.

Reckless Spite

Destroy two target nonblack creatures. You lose 5 life.

Essence Pulse

You gain 2 life. Each creature gets -X/-X until end of turn, where X is the amount of life you gained this turn.

Henrika, Infernal Seer

Flying, deathtouch, lifelink
{1}{B}{B}: Each creature you control with flying, deathtouch, and/or lifelink gets +1/+0 until end of turn.

Henrika Domnathi

Flying
At the beginning of combat on your turn, choose one that hasn't been chosen —
• Each player sacrifices a creature.
• You draw a card and you lose 1 life.
• Transform Henrika Domnathi.

Henrika Domnathi // Henrika, Infernal Seer

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When Murderous Rider dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Momentous Fall

As an additional cost to cast this spell, sacrifice a creature.
You draw cards equal to the sacrificed creature's power, then you gain life equal to its toughness.

Forest

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Verdant Sun's Avatar

Whenever Verdant Sun's Avatar or another creature enters the battlefield under your control, you gain life equal to that creature's toughness.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Paradise Plume

As Paradise Plume enters the battlefield, choose a color.
Whenever a player casts a spell of the chosen color, you may gain 1 life.
{T}: Add one mana of the chosen color.

Pest Infestation

Destroy up to X target artifacts and/or enchantments. Create twice X 1/1 black and green Pest creature tokens with "When this creature dies, you gain 1 life."

Lisette, Dean of the Root

Whenever you gain life, you may pay {1}. If you do, put a +1/+1 counter on each creature you control and those creatures gain trample until end of turn.

Valentin, Dean of the Vein

Menace, lifelink
If a nontoken creature an opponent controls would die, exile it instead. When you do, you may pay {2}. If you do, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."

Valentin, Dean of the Vein // Lisette, Dean of the Root

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Golgari Rot Farm

Golgari Rot Farm enters the battlefield tapped.
When Golgari Rot Farm enters the battlefield, return a land you control to its owner's hand.
{T}: Add {B}{G}.

Mirror Shield

Equipped creature gets +0/+2 and has hexproof and "Whenever a creature with deathtouch blocks or becomes blocked by this creature, destroy that creature."
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Willowdusk, Essence Seer

{1}, {T}: Choose another target creature. Put a number of +1/+1 counters on it equal to the amount of life you gained this turn or the amount of life you lost this turn, whichever is greater. Activate only as a sorcery.

Return of the Wildspeaker

Choose one —
• Draw cards equal to the greatest power among non-Human creatures you control.
• Non-Human creatures you control get +3/+3 until end of turn.

Gift of Paradise

Enchant land
When Gift of Paradise enters the battlefield, you gain 3 life.
Enchanted land has "{T}: Add two mana of any one color."

Honor Troll

Vigilance
If you would gain life, you gain that much life plus 1 instead.
Honor Troll gets +2/+1 as long as you have 25 or more life.

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Infuse with Vitality

Until end of turn, target creature gains deathtouch and "When this creature dies, return it to the battlefield tapped under its owner's control."
You gain 2 life.

Gyome, Master Chef

Trample
At the beginning of your end step, create a number of Food tokens equal to the number of nontoken creatures you had enter the battlefield under your control this turn.
{1}, Sacrifice a Food: Target creature gains indestructible until end of turn. Tap it.

Nullpriest of Oblivion

Kicker {3}{B}
Menace, lifelink
When Nullpriest of Oblivion enters the battlefield, if it was kicked, return target creature card from your graveyard to the battlefield.

Noxious Revival

({G/P} can be paid with either {G} or 2 life.)
Put target card from a graveyard on top of its owner's library.

Green Sun's Zenith

Search your library for a green creature card with mana value X or less, put it onto the battlefield, then shuffle. Shuffle Green Sun's Zenith into its owner's library.

Sheltering Word

Target creature you control gains hexproof until end of turn. You gain life equal to that creature's toughness. (A creature with hexproof can't be the target of spells or abilities your opponents control.)

Damnable Pact

Target player draws X cards and loses X life.

Maze of Ith

{T}: Untap target attacking creature. Prevent all combat damage that would be dealt to and dealt by that creature this turn.

Healing Technique

Demonstrate (When you cast this spell, you may copy it. If you do, choose an opponent to also copy it. Players may choose new targets for their copies.)
Return target card from your graveyard to your hand. You gain life equal to that card's mana value. Exile Healing Technique.

Haywire Mite

When Haywire Mite dies, you gain 2 life.
{G}, Sacrifice Haywire Mite: Exile target noncreature artifact or noncreature enchantment.

Sun Droplet

Whenever you're dealt damage, put that many charge counters on Sun Droplet.
At the beginning of each upkeep, you may remove a charge counter from Sun Droplet. If you do, you gain 1 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Nighthawk Scavenger

Flying, deathtouch, lifelink
Nighthawk Scavenger's power is equal to 1 plus the number of card types among cards in your opponents' graveyards.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Essence Harvest

Target player loses X life and you gain X life, where X is the greatest power among creatures you control.

Sapseep Forest

({T}: Add {G}.)
Sapseep Forest enters the battlefield tapped.
{G}, {T}: You gain 1 life. Activate only if you control two or more green permanents.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Gyre Sage

Evolve (Whenever a creature enters the battlefield under your control, if that creature has greater power or toughness than this creature, put a +1/+1 counter on this creature.)
{T}: Add {G} for each +1/+1 counter on Gyre Sage.

Sapling of Colfenor

Indestructible
Whenever Sapling of Colfenor attacks, reveal the top card of your library. If it's a creature card, you gain life equal to that card's toughness, lose life equal to its power, then put it into your hand.

Jungle Hollow

Jungle Hollow enters the battlefield tapped.
When Jungle Hollow enters the battlefield, you gain 1 life.
{T}: Add {B} or {G}.

Night's Whisper

Tamiyo's Safekeeping

Target permanent you control gains hexproof and indestructible until end of turn. You gain 2 life. (A permanent with hexproof and indestructible can't be the target of spells or abilities your opponents control. Damage and effects that say "destroy" don't destroy it.)

Slippery Bogbonder

Flash
Hexproof
When Slippery Bogbonder enters the battlefield, put a hexproof counter on target creature. Then move any number of counters from among creatures you control onto that creature.

Street Wraith

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
Cycling—Pay 2 life. (Pay 2 life, Discard this card: Draw a card.)

Marshland Bloodcaster

Flying
{1}{B}, {T}: Rather than pay the mana cost of the next spell you cast this turn, you may pay life equal to that spell's mana value.

Leyline Prowler

Deathtouch, lifelink
{T}: Add one mana of any color.

Tend the Pests

As an additional cost to cast this spell, sacrifice a creature.
Create X 1/1 black and green Pest creature tokens with "When this creature dies, you gain 1 life," where X is the sacrificed creature's power.

Infernal Grasp

Destroy target creature. You lose 2 life.

Accomplished Alchemist

{T}: Add one mana of any color.
{T}: Add X mana of any one color, where X is the amount of life you gained this turn.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Rampant Growth

Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Llanowar Wastes

{T}: Add {C}.
{T}: Add {B} or {G}. Llanowar Wastes deals 1 damage to you.

Blight Mound

Attacking Pests you control get +1/+0 and have menace.
Whenever a nontoken creature you control dies, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."

Swamp

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Force of Despair

If it's not your turn, you may exile a black card from your hand rather than pay this spell's mana cost.
Destroy all creatures that entered the battlefield this turn.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Mortality Spear

This spell costs {2} less to cast if you gained life this turn.
Destroy target nonland permanent.

Greed

Taste of Death

Each player sacrifices three creatures. You create three Food tokens. (They're artifacts with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Veinwitch Coven

Menace
Whenever you gain life, you may pay {B}. If you do, return target creature card from your graveyard to your hand.

Ancient Craving

You draw three cards and you lose 3 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Sign in Blood

Target player draws two cards and loses 2 life.

Witch's Clinic

{T}: Add {C}.
{2}, {T}: Target commander gains lifelink until end of turn.

Vampire Nighthawk

Moldering Karok

Vampire Scrivener

Flying
Whenever you gain life during your turn, put a +1/+1 counter on Vampire Scrivener.
Whenever you lose life during your turn, put a +1/+1 counter on Vampire Scrivener.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Druidic Satchel

{2}, {T}: Reveal the top card of your library. If it's a creature card, create a 1/1 green Saproling creature token. If it's a land card, put that card onto the battlefield under your control. If it's a noncreature, nonland card, you gain 2 life.

Witherbloom Campus

Witherbloom Campus enters the battlefield tapped.
{T}: Add {B} or {G}.
{4}, {T}: Scry 1.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Blighted Woodland

{T}: Add {C}.
{3}{G}, {T}, Sacrifice Blighted Woodland: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Bloodtracker

Flying
{B}, Pay 2 life: Put a +1/+1 counter on Bloodtracker.
When Bloodtracker leaves the battlefield, draw a card for each +1/+1 counter on it.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Revival Experiment

For each permanent type, return up to one card of that type from your graveyard to the battlefield. You lose 3 life for each card returned this way. Exile Revival Experiment.

Arboreal Grazer

Reach
When Arboreal Grazer enters the battlefield, you may put a land card from your hand onto the battlefield tapped.

Vault Skirge

({B/P} can be paid with either {B} or 2 life.)
Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Study Hall

{T}: Add {C}.
{1}, {T}: Add one mana of any color. When you spend this mana to cast your commander, scry X, where X is the number of times it's been cast from the command zone this game.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Sproutback Trudge

This spell costs {X} less to cast, where X is the amount of life you gained this turn.
Trample
At the beginning of your end step, if you gained life this turn, you may cast Sproutback Trudge from your graveyard.

High Market

{T}: Add {C}.
{T}, Sacrifice a creature: You gain 1 life.

Silversmote Ghoul

At the beginning of your end step, if you gained 3 or more life this turn, return Silversmote Ghoul from your graveyard to the battlefield tapped.
{1}{B}, Sacrifice Silversmote Ghoul: Draw a card.

Dina, Soul Steeper

Whenever you gain life, each opponent loses 1 life.
{1}, Sacrifice another creature: Dina, Soul Steeper gets +X/+0 until end of turn, where X is the sacrificed creature's power.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Mask of Griselbrand

Equipped creature has flying and lifelink.
Whenever equipped creature dies, you may pay X life, where X is its power. If you do, draw X cards.
Equip {3}

Malakir Mire

Malakir Mire enters the battlefield tapped.
{T}: Add {B}.

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

Talisman of Resilience

{T}: Add {C}.
{T}: Add {B} or {G}. Talisman of Resilience deals 1 damage to you.