Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Norn's Decree

Whenever one or more creatures an opponent controls deal combat damage to you, that opponent gets a poison counter.
Whenever a player attacks, if one or more players being attacked are poisoned, the attacking player draws a card.

The Great Synthesis

(As this Saga enters and after your draw step, add a lore counter.)
I — Draw cards equal to the number of cards in your hand. You have no maximum hand size for as long as you control The Great Synthesis.
II — Return all non-Phyrexian creatures to their owners' hands.
III — You may cast any number of spells from your hand without paying their mana costs. Exile The Great Synthesis, then return it to the battlefield (front face up).

Jin-Gitaxias

Ward {2}
Whenever you cast a noncreature spell with mana value 3 or greater, draw a card.
{3}{U}: Exile Jin-Gitaxias, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery and only if you have seven or more cards in hand.

Jin-Gitaxias // The Great Synthesis

Charge of the Mites

Choose one —
• Charge of the Mites deals damage equal to the number of creatures you control to target creature or planeswalker.
• Create two 1/1 colorless Phyrexian Mite artifact creature tokens with toxic 1 and "This creature can't block." (Players dealt combat damage by them also get a poison counter.)

Mesmerizing Dose

Enchant creature
When Mesmerizing Dose enters, tap enchanted creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Enchanted creature doesn't untap during its controller's untap step.

Annex Sentry

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Annex Sentry enters, exile target artifact or creature an opponent controls with mana value 3 or less until Annex Sentry leaves the battlefield.

Proper Burial

Whenever a creature you control dies, you gain life equal to that creature's toughness.

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Grim Haruspex

Morph {B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
Whenever another nontoken creature you control dies, draw a card.

Entomb

Search your library for a card, put that card into your graveyard, then shuffle.

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters, you may pay 2 life. If you don't, it enters tapped.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Grateful Apparition

Flying
Whenever Grateful Apparition deals combat damage to a player or planeswalker, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Drivnod, Carnage Dominus

If a creature dying causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.
{B/P}{B/P}, Exile three creature cards from your graveyard: Put an indestructible counter on Drivnod, Carnage Dominus. ({B/P} can be paid with either {B} or 2 life.)

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Tekuthal, Inquiry Dominus

Flying
If you would proliferate, proliferate twice instead.
{1}{U/P}{U/P}, Remove three counters from among other artifacts, creatures, and planeswalkers you control: Put an indestructible counter on Tekuthal, Inquiry Dominus. ({U/P} can be paid with either {U} or 2 life.)

Soul Warden

Whenever another creature enters, you gain 1 life.

Raffine's Tower

({T}: Add {W}, {U}, or {B}.)
Raffine's Tower enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Toxrill, the Corrosive

At the beginning of each end step, put a slime counter on each creature you don't control.
Creatures you don't control get -1/-1 for each slime counter on them.
Whenever a creature you don't control with a slime counter on it dies, create a 1/1 black Slug creature token.
{U}{B}, Sacrifice a Slug: Draw a card.

Jin-Gitaxias, Core Augur

Flash
At the beginning of your end step, draw seven cards.
Each opponent's maximum hand size is reduced by seven.

Plains

Corpse Knight

Whenever another creature you control enters, each opponent loses 1 life.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Anoint with Affliction

Exile target creature if it has mana value 3 or less.
Corrupted — Exile that creature instead if its controller has three or more poison counters.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Jin-Gitaxias, Progress Tyrant

Whenever you cast an artifact, instant, or sorcery spell, copy that spell. You may choose new targets for the copy. This ability triggers only once each turn. (A copy of a permanent spell becomes a token.)
Whenever an opponent casts an artifact, instant, or sorcery spell, counter that spell. This ability triggers only once each turn.

Sea of Clouds

Sea of Clouds enters tapped unless you have two or more opponents.
{T}: Add {W} or {U}.

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Phantasmal Image

You may have Phantasmal Image enter as a copy of any creature on the battlefield, except it's an Illusion in addition to its other types and it has "When this creature becomes the target of a spell or ability, sacrifice it."

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Sol Ring

Swamp

Ashnod's Altar

Myrel, Shield of Argive

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.
Whenever Myrel, Shield of Argive attacks, create X 1/1 colorless Soldier artifact creature tokens, where X is the number of Soldiers you control.

Living Death

Each player exiles all creature cards from their graveyard, then sacrifices all creatures they control, then puts all cards they exiled this way onto the battlefield.

Phyrexian Altar

Sacrifice a creature: Add one mana of any color.

Skrelv's Hive

At the beginning of your upkeep, you lose 1 life and create a 1/1 colorless Phyrexian Mite artifact creature token with toxic 1 and "This creature can't block."
Corrupted — As long as an opponent has three or more poison counters, creatures you control with toxic have lifelink.

Teysa Karlov

If a creature dying causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.
Creature tokens you control have vigilance and lifelink.

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Island

Venser, Corpse Puppet

Lifelink, toxic 1
Whenever you proliferate, choose one —
• If you don't control a creature named The Hollow Sentinel, create The Hollow Sentinel, a legendary 3/3 colorless Phyrexian Golem artifact creature token.
• Target artifact creature you control gains flying and lifelink until end of turn.

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Nadir Kraken

Whenever you draw a card, you may pay {1}. If you do, put a +1/+1 counter on Nadir Kraken and create a 1/1 blue Tentacle creature token.

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Faithful Mending

You gain 2 life, draw two cards, then discard two cards.
Flashback {1}{W}{U} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Karmic Guide

Flying, protection from black
Echo {3}{W}{W} (At the beginning of your upkeep, if this came under your control since the beginning of your last upkeep, sacrifice it unless you pay its echo cost.)
When Karmic Guide enters, return target creature card from your graveyard to the battlefield.

The Seedcore

{T}: Add {C}.
{T}: Add one mana of any color. Spend this mana only to cast Phyrexian creature spells.
Corrupted — {T}: Target 1/1 creature gets +2/+1 until end of turn. Activate only if an opponent has three or more poison counters.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Mondrak, Glory Dominus

If one or more tokens would be created under your control, twice that many of those tokens are created instead.
{1}{W/P}{W/P}, Sacrifice two other artifacts and/or creatures: Put an indestructible counter on Mondrak, Glory Dominus. ({W/P} can be paid with either {W} or 2 life.)

Elesh Norn, Grand Cenobite

Vigilance
Other creatures you control get +2/+2.
Creatures your opponents control get -2/-2.

Eloise, Nephalia Sleuth

Whenever another creature you control dies, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")
Whenever you sacrifice a token, surveil 1. (Look at the top card of your library. You may put that card into your graveyard.)

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature of their choice.

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Contentious Plan

Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Draw a card.

Vindictive Vampire

Whenever another creature you control dies, Vindictive Vampire deals 1 damage to each opponent and you gain 1 life.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Guildpact Informant

Flying
Whenever Guildpact Informant deals combat damage to a player or planeswalker, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Deserted Beach

Deserted Beach enters tapped unless you control two or more other lands.
{T}: Add {W} or {U}.

Aminatou, the Fateshifter

+1: Draw a card, then put a card from your hand on top of your library.
−1: Exile another target permanent you own, then return it to the battlefield under your control.
−6: Choose left or right. Each player gains control of all nonland permanents other than Aminatou, the Fateshifter controlled by the next player in the chosen direction.
Aminatou, the Fateshifter can be your commander.

Mirrex

{T}: Add {C}.
{T}: Add one mana of any color. Activate only if Mirrex entered this turn.
{3}, {T}: Create a 1/1 colorless Phyrexian Mite artifact creature token with toxic 1 and "This creature can't block." (Players dealt combat damage by it also get a poison counter.)

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Panharmonicon

If an artifact or creature entering causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.

Scheming Aspirant

Whenever you proliferate, each opponent loses 2 life and you gain 2 life.

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Serra's Emissary

Flying
As Serra's Emissary enters, choose a card type.
You and creatures you control have protection from the chosen card type.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Elesh Norn, Mother of Machines

Vigilance
If a permanent entering causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.
Permanents entering don't cause abilities of permanents your opponents control to trigger.

Anointed Procession

If an effect would create one or more tokens under your control, it creates twice that many of those tokens instead.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)