Damnation

Destroy all creatures. They can't be regenerated.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Polluted Mire

Polluted Mire enters tapped.
{T}: Add {B}.
Cycling {2} ({2}, Discard this card: Draw a card.)

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When Murderous Rider dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Great Unclean One

Reverberating Summons — At the beginning of your end step, each opponent loses 2 life. Then for each opponent who has less life than you, create a 1/3 black Demon creature token named Plaguebearer of Nurgle.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Vendetta

Destroy target nonblack creature. It can't be regenerated. You lose life equal to that creature's toughness.

Devour in Shadow

Destroy target creature. It can't be regenerated. You lose life equal to that creature's toughness.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

Pointed Discussion

You draw two cards, lose 2 life, then create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Zulaport Cutthroat

Whenever Zulaport Cutthroat or another creature you control dies, each opponent loses 1 life and you gain 1 life.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Mortarion, Daemon Primarch

Flying
Primarch of the Death Guard — At the beginning of your end step, you may pay {X}. If you do, create X 2/2 black Astartes Warrior creature tokens with menace. X can't be greater than the amount of life you lost this turn.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Night's Whisper

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Mikaeus, the Unhallowed

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Whenever a Human deals damage to you, destroy it.
Other non-Human creatures you control get +1/+1 and have undying. (When a creature with undying dies, if it had no +1/+1 counters on it, return it to the battlefield under its owner's control with a +1/+1 counter on it.)

Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Carrion Feeder

Carrion Feeder can't block.
Sacrifice a creature: Put a +1/+1 counter on Carrion Feeder.

Swamp

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Raiders' Spoils

Creatures you control get +1/+0.
Whenever a Warrior you control deals combat damage to a player, you may pay 1 life. If you do, draw a card.

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ophiomancer

At the beginning of each upkeep, if you control no Snakes, create a 1/1 black Snake creature token with deathtouch.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Infernal Grasp

Destroy target creature. You lose 2 life.

Thrasher Brute

Whenever Thrasher Brute or another Warrior your team controls enters, target opponent loses 1 life and you gain 1 life.

Desert of the Glorified

Desert of the Glorified enters tapped.
{T}: Add {B}.
Cycling {1}{B} ({1}{B}, Discard this card: Draw a card.)

Chainer, Dementia Master

All Nightmares get +1/+1.
{B}{B}{B}, Pay 3 life: Put target creature card from a graveyard onto the battlefield under your control. That creature is black and is a Nightmare in addition to its other creature types.
When Chainer, Dementia Master leaves the battlefield, exile all Nightmares.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Sol Ring

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Plague of Vermin

Starting with you, each player may pay any amount of life. Repeat this process until no one pays life. Each player creates a 1/1 black Rat creature token for each 1 life they paid this way.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Go for the Throat

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Barren Moor

Barren Moor enters tapped.
{T}: Add {B}.
Cycling {B} ({B}, Discard this card: Draw a card.)

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Putrid Goblin

Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Sign in Blood

Target player draws two cards and loses 2 life.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Phyrexian Altar

Sacrifice a creature: Add one mana of any color.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Mindblade Render

Whenever your opponents are dealt combat damage, if any of that damage was dealt by a Warrior, you draw a card and you lose 1 life.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.