Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ugin, the Ineffable

Colorless spells you cast cost {2} less to cast.
+1: Exile the top card of your library face down and look at it. Create a 2/2 colorless Spirit creature token. When that token leaves the battlefield, put the exiled card into your hand.
−3: Destroy target permanent that's one or more colors.

Plains

Ob Nixilis Reignited

+1: You draw a card and you lose 1 life.
−3: Destroy target creature.
−8: Target opponent gets an emblem with "Whenever a player draws a card, you lose 2 life."

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Black Market Connections

At the beginning of your precombat main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Semester's End

Exile any number of target creatures and/or planeswalkers you control. At the beginning of the next end step, return each of them to the battlefield under its owner's control. Each of them enters the battlefield with an additional +1/+1 counter on it if it's a creature and an additional loyalty counter on it if it's a planeswalker.

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters the battlefield tapped unless you control two or more basic lands.

Isolated Chapel

Isolated Chapel enters the battlefield tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Sorin the Mirthless

+1: Look at the top card of your library. You may reveal that card and put it into your hand. If you do, you lose life equal to its mana value.
−2: Create a 2/3 black Vampire creature token with flying and lifelink.
−7: Sorin the Mirthless deals 13 damage to any target. You gain 13 life.

Silent Clearing

{T}, Pay 1 life: Add {W} or {B}.
{1}, {T}, Sacrifice Silent Clearing: Draw a card.

Skullclamp

Equipped creature gets +1/-1.
Whenever equipped creature dies, draw two cards.
Equip {1}

Clifftop Retreat

Clifftop Retreat enters the battlefield tapped unless you control a Mountain or a Plains.
{T}: Add {R} or {W}.

Damnation

Destroy all creatures. They can't be regenerated.

Liliana, the Last Hope

+1: Up to one target creature gets -2/-1 until your next turn.
−2: Mill two cards, then you may return a creature card from your graveyard to your hand.
−7: You get an emblem with "At the beginning of your end step, create X 2/2 black Zombie creature tokens, where X is two plus the number of Zombies you control."

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Queen Marchesa

Deathtouch, haste
When Queen Marchesa enters the battlefield, you become the monarch.
At the beginning of your upkeep, if an opponent is the monarch, create a 1/1 black Assassin creature token with deathtouch and haste.

Interplanar Beacon

Whenever you cast a planeswalker spell, you gain 1 life.
{T}: Add {C}.
{1}, {T}: Add two mana of different colors. Spend this mana only to cast planeswalker spells.

Bojuka Bog

Bojuka Bog enters the battlefield tapped.
When Bojuka Bog enters the battlefield, exile target player's graveyard.
{T}: Add {B}.

Lae'zel, Vlaakith's Champion

If you would put one or more counters on a creature or planeswalker you control or on yourself, put that many plus one of each of those kinds of counters on that permanent or player instead.
Choose a Background (You can have a Background as a second commander.)

Vraska, Betrayal's Sting

Compleated ({B/P} can be paid with {B} or 2 life. If life was paid, this planeswalker enters with two fewer loyalty counters.)
0: You draw a card and you lose 1 life. Proliferate.
−2: Target creature becomes a Treasure artifact with "{T}, Sacrifice this artifact: Add one mana of any color" and loses all other card types and abilities.
−9: If target player has fewer than nine poison counters, they get a number of poison counters equal to the difference.

Arena Rector

When Arena Rector dies, you may exile it. If you do, search your library for a planeswalker card, put it onto the battlefield, then shuffle.

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters the battlefield with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Spires of Orazca

(Transforms from Thaumatic Compass.)
{T}: Add {C}.
{T}: Untap target attacking creature an opponent controls and remove it from combat.

Thaumatic Compass

{3}, {T}: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.
At the beginning of your end step, if you control seven or more lands, transform Thaumatic Compass.

Thaumatic Compass // Spires of Orazca

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Fire Covenant

As an additional cost to cast this spell, pay X life.
Fire Covenant deals X damage divided as you choose among any number of target creatures.

Burnished Hart

{3}, Sacrifice Burnished Hart: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Savai Triome

({T}: Add {R}, {W}, or {B}.)
Savai Triome enters the battlefield tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Lukka, Wayward Bonder

+1: You may discard a card. If you do, draw a card. If a creature card was discarded this way, draw two cards instead.
−2: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of your next upkeep.
−7: You get an emblem with "Whenever a creature enters the battlefield under your control, it deals damage equal to its power to any target."

Mila, Crafty Companion

Whenever an opponent attacks one or more planeswalkers you control, put a loyalty counter on each planeswalker you control.
Whenever a permanent you control becomes the target of a spell or ability an opponent controls, you may draw a card.

Mila, Crafty Companion // Lukka, Wayward Bonder

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Crystalline Crawler

Converge — Crystalline Crawler enters the battlefield with a +1/+1 counter on it for each color of mana spent to cast it.
Remove a +1/+1 counter from Crystalline Crawler: Add one mana of any color.
{T}: Put a +1/+1 counter on Crystalline Crawler.

Sorin, Lord of Innistrad

+1: Create a 1/1 black Vampire creature token with lifelink.
−2: You get an emblem with "Creatures you control get +1/+0."
−6: Destroy up to three target creatures and/or other planeswalkers. Return each card put into a graveyard this way to the battlefield under your control.

Grateful Apparition

Flying
Whenever Grateful Apparition deals combat damage to a player or planeswalker, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Solemn Simulacrum

When Solemn Simulacrum enters the battlefield, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Liliana of the Veil

+1: Each player discards a card.
−2: Target player sacrifices a creature.
−6: Separate all permanents target player controls into two piles. That player sacrifices all permanents in the pile of their choice.

Chandra, Awakened Inferno

This spell can't be countered.
+2: Each opponent gets an emblem with "At the beginning of your upkeep, this emblem deals 1 damage to you."
−3: Chandra, Awakened Inferno deals 3 damage to each non-Elemental creature.
−X: Chandra, Awakened Inferno deals X damage to target creature or planeswalker. If a permanent dealt damage this way would die this turn, exile it instead.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Settle the Score

Exile target creature. Put two loyalty counters on a planeswalker you control.

Tibalt, Cosmic Impostor

As Tibalt enters the battlefield, you get an emblem with "You may play cards exiled with Tibalt, Cosmic Impostor, and you may spend mana as though it were mana of any color to cast those spells."
+2: Exile the top card of each player's library.
−3: Exile target artifact or creature.
−8: Exile all graveyards. Add {R}{R}{R}.

Valki, God of Lies

When Valki enters the battlefield, each opponent reveals their hand. For each opponent, exile a creature card they revealed this way until Valki leaves the battlefield.
{X}: Choose a creature card exiled with Valki with mana value X. Valki becomes a copy of that card.

Valki, God of Lies // Tibalt, Cosmic Impostor

Ugin, the Spirit Dragon

+2: Ugin, the Spirit Dragon deals 3 damage to any target.
−X: Exile each permanent with mana value X or less that's one or more colors.
−10: You gain 7 life, draw seven cards, then put up to seven permanent cards from your hand onto the battlefield.

Sol Ring

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Oath of Gideon

When Oath of Gideon enters the battlefield, create two 1/1 white Kor Ally creature tokens.
Each planeswalker you control enters the battlefield with an additional loyalty counter on it.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Astral Cornucopia

Astral Cornucopia enters the battlefield with X charge counters on it.
{T}: Choose a color. Add one mana of that color for each charge counter on Astral Cornucopia.

Sunbaked Canyon

{T}, Pay 1 life: Add {R} or {W}.
{1}, {T}, Sacrifice Sunbaked Canyon: Draw a card.

Oath of Liliana

When Oath of Liliana enters the battlefield, each opponent sacrifices a creature.
At the beginning of each end step, if a planeswalker entered the battlefield under your control this turn, create a 2/2 black Zombie creature token.

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Shinka, the Bloodsoaked Keep

{T}: Add {R}.
{R}, {T}: Target legendary creature gains first strike until end of turn.

Sacred Foundry

({T}: Add {R} or {W}.)
As Sacred Foundry enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Ophiomancer

At the beginning of each upkeep, if you control no Snakes, create a 1/1 black Snake creature token with deathtouch.

Daretti, Ingenious Iconoclast

+1: Create a 1/1 colorless Construct artifact creature token with defender.
−1: You may sacrifice an artifact. If you do, destroy target artifact or creature.
−6: Choose target artifact card in a graveyard or artifact on the battlefield. Create three tokens that are copies of it.

Mountain

Urza Assembles the Titans

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Scry 4, then you may reveal the top card of your library. If a planeswalker card is revealed this way, put it into your hand.
II — You may put a planeswalker card with mana value 6 or less from your hand onto the battlefield.
III — You may activate the loyalty abilities of planeswalkers you control twice this turn rather than only once.

Loyal Warhound

Vigilance
When Loyal Warhound enters the battlefield, if an opponent controls more lands than you, search your library for a basic Plains card, put it onto the battlefield tapped, then shuffle.

The Elderspell

Destroy any number of target planeswalkers. Choose a planeswalker you control. Put two loyalty counters on it for each planeswalker destroyed this way.

Myriad Landscape

Myriad Landscape enters the battlefield tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Elspeth, Sun's Champion

+1: Create three 1/1 white Soldier creature tokens.
−3: Destroy all creatures with power 4 or greater.
−7: You get an emblem with "Creatures you control get +2/+2 and have flying."

Vanquish the Horde

This spell costs {1} less to cast for each creature on the battlefield.
Destroy all creatures.

Rakdos Signet

Swamp

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Elspeth, Knight-Errant

+1: Create a 1/1 white Soldier creature token.
+1: Target creature gets +3/+3 and gains flying until end of turn.
−8: You get an emblem with "Artifacts, creatures, enchantments, and lands you control have indestructible."

The Chain Veil

At the beginning of your end step, if you didn't activate a loyalty ability of a planeswalker this turn, you lose 2 life.
{4}, {T}: For each planeswalker you control, you may activate one of its loyalty abilities once this turn as though none of its loyalty abilities have been activated this turn.

Knight of the White Orchid

First strike
When Knight of the White Orchid enters the battlefield, if an opponent controls more lands than you, you may search your library for a Plains card, put it onto the battlefield, then shuffle.

Chandra, Torch of Defiance

+1: Exile the top card of your library. You may cast that card. If you don't, Chandra, Torch of Defiance deals 2 damage to each opponent.
+1: Add {R}{R}.
−3: Chandra, Torch of Defiance deals 4 damage to target creature.
−7: You get an emblem with "Whenever you cast a spell, this emblem deals 5 damage to any target."

The Wandering Emperor

Flash
As long as The Wandering Emperor entered the battlefield this turn, you may activate her loyalty abilities any time you could cast an instant.
+1: Put a +1/+1 counter on up to one target creature. It gains first strike until end of turn.
−1: Create a 2/2 white Samurai creature token with vigilance.
−2: Exile target tapped creature. You gain 2 life.

Command Tower

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters the battlefield, you may pay 2 life. If you don't, it enters the battlefield tapped.

Dragonskull Summit

Dragonskull Summit enters the battlefield tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Orzhov Signet

Throne of Geth

{T}, Sacrifice an artifact: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Repeated Reverberation

When you next cast an instant spell, cast a sorcery spell, or activate a loyalty ability this turn, copy that spell or ability twice. You may choose new targets for the copies.

Boros Signet

Deep Gnome Terramancer

Flash
Mold Earth — Whenever one or more lands enter the battlefield under an opponent's control without being played, you may search your library for a Plains card, put it onto the battlefield tapped, then shuffle. Do this only once each turn.

Lolth, Spider Queen

Whenever a creature you control dies, put a loyalty counter on Lolth, Spider Queen.
0: You draw a card and you lose 1 life.
−3: Create two 2/1 black Spider creature tokens with menace and reach.
−8: You get an emblem with "Whenever an opponent is dealt combat damage by one or more creatures you control, if that player lost less than 8 life this turn, they lose life equal to the difference."