Sign in Blood

Target player draws two cards and loses 2 life.

Castle Vantress

Castle Vantress enters tapped unless you control an Island.
{T}: Add {U}.
{2}{U}{U}, {T}: Scry 2.

Taniwha

Trample
Phasing (This phases in or out before you untap during each of your untap steps. While it's phased out, it's treated as though it doesn't exist.)
At the beginning of your upkeep, all lands you control phase out. (They phase in before you untap during your next untap step.)

Cunning Rhetoric

Whenever an opponent attacks you and/or one or more planeswalkers you control, exile the top card of that player's library. You may play that card for as long as it remains exiled, and you may spend mana as though it were mana of any color to cast it.

Yukora, the Prisoner

When Yukora, the Prisoner leaves the battlefield, sacrifice all non-Ogre creatures you control.

Grid Monitor

Drinker of Sorrow

Drinker of Sorrow can't block.
Whenever Drinker of Sorrow deals combat damage, sacrifice a permanent.

Charcoal Diamond

Charcoal Diamond enters tapped.
{T}: Add {B}.

Abyssal Persecutor

Flying, trample
You can't win the game and your opponents can't lose the game.

Puca's Mischief

At the beginning of your upkeep, you may exchange control of target nonland permanent you control and target nonland permanent an opponent controls with equal or lesser mana value.

Flesh Reaver

Whenever Flesh Reaver deals damage to a creature or opponent, Flesh Reaver deals that much damage to you.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

No Mercy

Whenever a creature deals damage to you, destroy it.

Evil Eye of Orms-by-Gore

Non-Eye creatures you control can't attack.
Evil Eye of Orms-by-Gore can't be blocked except by Walls.

Curse of Verbosity

Enchant player
Whenever enchanted player is attacked, you draw a card. Each opponent attacking that player does the same.

Reins of Power

Untap all creatures you control and all creatures target opponent controls. You and that opponent each gain control of all creatures the other controls until end of turn. Those creatures gain haste until end of turn.

Phyrexian Vatmother

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, you get a poison counter.

Phyrexian Negator

Trample
Whenever Phyrexian Negator is dealt damage, sacrifice that many permanents.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Infernal Grasp

Destroy target creature. You lose 2 life.

Legerdemain

Exchange control of target artifact or creature and another target permanent that shares one of those types with it. (This effect lasts indefinitely.)

Archfiend of the Dross

Flying
Archfiend of the Dross enters with four oil counters on it.
At the beginning of your upkeep, remove an oil counter from Archfiend of the Dross. Then if it has no oil counters on it, you lose the game.
Whenever a creature an opponent controls dies, its controller loses 2 life.

Phyrexian Metamorph

({U/P} can be paid with either {U} or 2 life.)
You may have Phyrexian Metamorph enter as a copy of any artifact or creature on the battlefield, except it's an artifact in addition to its other types.

Ebon Drake

Flying
Whenever a player casts a spell, you lose 1 life.

Priest of the Blood Rite

When Priest of the Blood Rite enters, create a 5/5 black Demon creature token with flying.
At the beginning of your upkeep, you lose 2 life.

Abhorrent Overlord

Flying
When Abhorrent Overlord enters, create a number of 1/1 black Harpy creature tokens with flying equal to your devotion to black. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
At the beginning of your upkeep, sacrifice a creature.

Sky Diamond

Asmodeus the Archfiend

Binding Contract — If you would draw a card, exile the top card of your library face down instead.
{B}{B}{B}: Draw seven cards.
{B}: Return all cards exiled with Asmodeus the Archfiend to their owner's hand and you lose that much life.

Plague Reaver

At the beginning of your end step, sacrifice each other creature you control.
Discard two cards, Sacrifice Plague Reaver: Choose target opponent. Return Plague Reaver to the battlefield under that player's control at the beginning of their next upkeep.

Reflecting Pool

{T}: Add one mana of any type that a land you control could produce.

The Phasing of Zhalfir

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I, II — Another target nonland permanent phases out. It can't phase in for as long as you control The Phasing of Zhalfir.
III — Destroy all creatures. For each creature destroyed this way, its controller creates a 2/2 black Phyrexian creature token.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Greater Harvester

At the beginning of your upkeep, sacrifice a permanent.
Whenever Greater Harvester deals combat damage to a player, that player sacrifices two permanents of their choice.

Liege of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Liege of the Pit. If you can't, Liege of the Pit deals 7 damage to you.
Morph {B}{B}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Fateful Handoff

Draw cards equal to the mana value of target artifact or creature you control. An opponent gains control of that permanent.

Jon Irenicus, Shattered One

At the beginning of your end step, target opponent gains control of up to one target creature you control. Put two +1/+1 counters on it and tap it. It's goaded for the rest of the game and it gains "This creature can't be sacrificed." (It attacks each combat if able and attacks a player other than you if able.)
Whenever a creature you own but don't control attacks, you draw a card.

Wretched Anurid

Whenever another creature enters, you lose 1 life.

Contaminated Aquifer

({T}: Add {U} or {B}.)
Contaminated Aquifer enters tapped.

Maze of Ith

{T}: Untap target attacking creature. Prevent all combat damage that would be dealt to and dealt by that creature this turn.

Ebonblade Reaper

Whenever Ebonblade Reaper attacks, you lose half your life, rounded up.
Whenever Ebonblade Reaper deals combat damage to a player, that player loses half their life, rounded up.
Morph {3}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Sower of Discord

Flying
As Sower of Discord enters, choose two players.
Whenever damage is dealt to one of the chosen players, the other chosen player also loses that much life.

Night's Whisper

Mocking Doppelganger

Flash
You may have Mocking Doppelganger enter as a copy of a creature an opponent controls, except it has "Other creatures with the same name as this creature are goaded." (They attack each combat if able and attack a player other than you if able.)

Aetherize

Return all attacking creatures to their owner's hand.

Gisa, Glorious Resurrector

If a creature an opponent controls would die, exile it instead.
At the beginning of your upkeep, put all creature cards exiled with Gisa, Glorious Resurrector onto the battlefield under your control. They gain decayed. (A creature with decayed can't block. When it attacks, sacrifice it at end of combat.)

Steel Golem

Evacuation

Return all creatures to their owners' hands.

Callidus Assassin

Flash
Polymorphine — You may have Callidus Assassin enter tapped as a copy of any creature on the battlefield, except it has "When this creature enters, destroy up to one other target creature with the same name as this creature."

Teferi's Ageless Insight

If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Sudden Substitution

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Exchange control of target noncreature spell and target creature. Then the spell's controller may choose new targets for it.

Whelming Wave

Return all creatures to their owners' hands except for Krakens, Leviathans, Octopuses, and Serpents.

Lord of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Lord of the Pit. If you can't, Lord of the Pit deals 7 damage to you.

High Market

{T}: Add {C}.
{T}, Sacrifice a creature: You gain 1 life.

March of Swirling Mist

As an additional cost to cast this spell, you may exile any number of blue cards from your hand. This spell costs {2} less to cast for each card exiled this way.
Up to X target creatures phase out. (While they're phased out, they're treated as though they don't exist. Each one phases in before its controller untaps during their next untap step.)

Feign Death

Until end of turn, target creature gains "When this creature dies, return it to the battlefield tapped under its owner's control with a +1/+1 counter on it."

Rotting Regisaur

At the beginning of your upkeep, discard a card.

Clever Impersonator

You may have Clever Impersonator enter as a copy of any nonland permanent on the battlefield.

Hellcarver Demon

Flying
Whenever Hellcarver Demon deals combat damage to a player, sacrifice all other permanents you control and discard your hand. Exile the top six cards of your library. You may cast any number of spells from among cards exiled this way without paying their mana costs.

Persist

Return target nonlegendary creature card from your graveyard to the battlefield with a -1/-1 counter on it.

Despotic Scepter

{T}: Destroy target permanent you own. It can't be regenerated.

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Endless Whispers

Each creature has "When this creature dies, choose target opponent. That player puts this card from its owner's graveyard onto the battlefield under their control at the beginning of the next end step."

Modify Memory

Exchange control of two target creatures controlled by different players. If you control neither creature, draw three cards.

Evil Eye of Urborg

Non-Eye creatures you control can't attack.
Whenever Evil Eye of Urborg becomes blocked by a creature, destroy that creature.

Sol Ring

Domineering Will

Target player gains control of up to three target nonattacking creatures until end of turn. Untap those creatures. They block this turn if able.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Dissipation Field

Whenever a permanent deals damage to you, return it to its owner's hand.

Bloodthirsty Blade

Equipped creature gets +2/+0 and is goaded. (It attacks each combat if able and attacks a player other than you if able.)
{1}: Attach Bloodthirsty Blade to target creature an opponent controls. Activate only as a sorcery.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. Underground River deals 1 damage to you.

Rust Elemental

Flying
At the beginning of your upkeep, sacrifice an artifact other than Rust Elemental. If you can't, tap Rust Elemental and you lose 4 life.

Wrong Turn

Target opponent gains control of target creature. (If an attacking or blocking creature changes controllers, it's removed from combat.)

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Demonic Taskmaster

Flying
At the beginning of your upkeep, sacrifice a creature other than Demonic Taskmaster.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Heartless Summoning

Creature spells you cast cost {2} less to cast.
Creatures you control get -1/-1.