Liege of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Liege of the Pit. If you can't, Liege of the Pit deals 7 damage to you.
Morph {B}{B}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Lim-Dûl's Hex

At the beginning of your upkeep, for each player, Lim-Dûl's Hex deals 1 damage to that player unless they pay {B} or {3}.

Plague of Vermin

Starting with you, each player may pay any amount of life. Repeat this process until no one pays life. Each player creates a 1/1 black Rat creature token for each 1 life they paid this way.

Necrotic Plague

Enchant creature
Enchanted creature has "At the beginning of your upkeep, sacrifice this creature."
When enchanted creature dies, its controller chooses target creature one of their opponents controls. Return Necrotic Plague from its owner's graveyard to the battlefield attached to that creature.

Flesh Reaver

Whenever Flesh Reaver deals damage to a creature or opponent, Flesh Reaver deals that much damage to you.

Eternity Vessel

Eternity Vessel enters with X charge counters on it, where X is your life total.
Landfall — Whenever a land you control enters, you may have your life total become the number of charge counters on Eternity Vessel.

Sanctum of the Sun

(Transforms from Azor's Gateway.)
{T}: Add X mana of any one color, where X is your life total.

Azor's Gateway

{1}, {T}: Draw a card, then exile a card from your hand. If cards with five or more different mana values are exiled with Azor's Gateway, you gain 5 life, untap Azor's Gateway, and transform it.

Azor's Gateway // Sanctum of the Sun

Simulacrum

You gain life equal to the damage dealt to you this turn. Simulacrum deals damage to target creature you control equal to the damage dealt to you this turn.

Ebonblade Reaper

Whenever Ebonblade Reaper attacks, you lose half your life, rounded up.
Whenever Ebonblade Reaper deals combat damage to a player, that player loses half their life, rounded up.
Morph {3}{B}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Zombie Cannibal

Whenever Zombie Cannibal deals combat damage to a player, you may exile target card from that player's graveyard.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Banshee

{X}, {T}: Banshee deals half X damage, rounded down, to any target, and half X damage, rounded up, to you.

Bellowing Fiend

Flying
Whenever Bellowing Fiend deals damage to a creature, Bellowing Fiend deals 3 damage to that creature's controller and 3 damage to you.

Rancid Earth

Destroy target land.
Threshold — If seven or more cards are in your graveyard, instead destroy that land and Rancid Earth deals 1 damage to each creature and each player.

Kuro, Pitlord

At the beginning of your upkeep, sacrifice Kuro, Pitlord unless you pay {B}{B}{B}{B}.
Pay 1 life: Target creature gets -1/-1 until end of turn.

Titan Hunter

At the beginning of each player's end step, if no creatures died this turn, Titan Hunter deals 4 damage to that player.
{1}{B}, Sacrifice a creature: You gain 4 life.

Dark Bargain

Look at the top three cards of your library. Put two of them into your hand and the other into your graveyard. Dark Bargain deals 2 damage to you.

Traveling Plague

Enchant creature
At the beginning of each upkeep, put a plague counter on Traveling Plague.
Enchanted creature gets -1/-1 for each plague counter on Traveling Plague.
When enchanted creature leaves the battlefield, that creature's controller returns Traveling Plague from its owner's graveyard to the battlefield.

Midnight Reaper

Whenever a nontoken creature you control dies, this creature deals 1 damage to you and you draw a card.

Plague Sliver

All Slivers have "At the beginning of your upkeep, this permanent deals 1 damage to you."

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Lord of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Lord of the Pit. If you can't, Lord of the Pit deals 7 damage to you.

Blind Zealot

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Whenever Blind Zealot deals combat damage to a player, you may sacrifice it. If you do, destroy target creature that player controls.

Minion of Leshrac

Protection from black
At the beginning of your upkeep, Minion of Leshrac deals 5 damage to you unless you sacrifice a creature other than Minion of Leshrac. If Minion of Leshrac deals damage to you this way, tap it.
{T}: Destroy target creature or land.

Fledgling Djinn

Flying
At the beginning of your upkeep, Fledgling Djinn deals 1 damage to you.

Command the Dreadhorde

Choose any number of target creature and/or planeswalker cards in graveyards. Command the Dreadhorde deals damage to you equal to the total mana value of those cards. Put them onto the battlefield under your control.

Plague Spitter

At the beginning of your upkeep, Plague Spitter deals 1 damage to each creature and each player.
When Plague Spitter dies, it deals 1 damage to each creature and each player.

Rite of Belzenlok

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Create two 0/1 black Cleric creature tokens.
III — Create a 6/6 black Demon creature token with flying, trample, and "At the beginning of your upkeep, sacrifice another creature. If you can't, this creature deals 6 damage to you."

Endemic Plague

As an additional cost to cast this spell, sacrifice a creature.
Destroy all creatures that share a creature type with the sacrificed creature. They can't be regenerated.

Cosmic Horror

First strike
At the beginning of your upkeep, destroy Cosmic Horror unless you pay {3}{B}{B}{B}. If Cosmic Horror is destroyed this way, it deals 7 damage to you.

Vampire Scrivener

Flying
Whenever you gain life during your turn, put a +1/+1 counter on Vampire Scrivener.
Whenever you lose life during your turn, put a +1/+1 counter on Vampire Scrivener.

Hasran Ogress

Whenever Hasran Ogress attacks, it deals 3 damage to you unless you pay {2}.

Death's Shadow

Death's Shadow gets -X/-X, where X is your life total.

Archdemon of Greed

Flying, trample
At the beginning of your upkeep, sacrifice a Human. If you can't, tap Archdemon of Greed and it deals 9 damage to you.

Ravenous Demon

Sacrifice a Human: Transform Ravenous Demon. Activate only as a sorcery.

Ravenous Demon // Archdemon of Greed

Minion of Tevesh Szat

At the beginning of your upkeep, Minion of Tevesh Szat deals 2 damage to you unless you pay {B}{B}.
{T}: Target creature gets +3/-2 until end of turn.

Lich's Mirror

If you would lose the game, instead shuffle your hand, your graveyard, and all permanents you own into your library, then draw seven cards and your life total becomes 20.

Sengir, the Dark Baron

Flying
Whenever another creature dies, put two +1/+1 counters on Sengir, the Dark Baron.
Whenever another player loses the game, you gain life equal to that player's life total as the turn began.
Partner (You can have two commanders if both have partner.)

Roiling Horror

Roiling Horror's power and toughness are each equal to your life total minus the life total of an opponent with the most life.
Suspend X—{X}{B}{B}{B}. X can't be 0. (Rather than cast this card from your hand, you may pay {X}{B}{B}{B} and exile it with X time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost. It has haste.)
Whenever a time counter is removed from Roiling Horror while it's exiled, target player loses 1 life and you gain 1 life.

Vengeful Warchief

Whenever you lose life for the first time each turn, put a +1/+1 counter on Vengeful Warchief. (Damage causes loss of life.)

Phage the Untouchable

When Phage the Untouchable enters, if you didn't cast it from your hand, you lose the game.
Whenever Phage deals combat damage to a creature, destroy that creature. It can't be regenerated.
Whenever Phage deals combat damage to a player, that player loses the game.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Kothophed, Soul Hoarder

Flying
Whenever a permanent owned by another player is put into a graveyard from the battlefield, you draw a card and you lose 1 life.

Raving Dead

Deathtouch
At the beginning of combat on your turn, choose an opponent at random. Raving Dead attacks that player this combat if able.
Whenever Raving Dead deals combat damage to a player, that player loses half their life, rounded down.

Erg Raiders

At the beginning of your end step, if Erg Raiders didn't attack this turn, Erg Raiders deals 2 damage to you unless it came under your control this turn.

Lich's Tomb

You don't lose the game for having 0 or less life.
Whenever you lose life, sacrifice a permanent for each 1 life you lost. (Damage causes loss of life.)

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Demonic Pact

At the beginning of your upkeep, choose one that hasn't been chosen —
• This enchantment deals 4 damage to any target and you gain 4 life.
• Target opponent discards two cards.
• Draw two cards.
• You lose the game.

Carnival of Souls

Whenever a creature enters, you lose 1 life and add {B}.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Season of the Witch

At the beginning of your upkeep, sacrifice Season of the Witch unless you pay 2 life.
At the beginning of the end step, destroy all untapped creatures that didn't attack this turn, except for creatures that couldn't attack.

Sleeper Agent

When Sleeper Agent enters, target opponent gains control of it.
At the beginning of your upkeep, Sleeper Agent deals 2 damage to you.

Blade Juggler

Spectacle {2}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
When Blade Juggler enters, it deals 1 damage to you and you draw a card.

Measure of Wickedness

At the beginning of your end step, sacrifice Measure of Wickedness and you lose 8 life.
Whenever another card is put into your graveyard from anywhere, target opponent gains control of Measure of Wickedness.

Kezzerdrix

First strike
At the beginning of your upkeep, if your opponents control no creatures, Kezzerdrix deals 4 damage to you.

Demonlord Belzenlok

Flying, trample
When Demonlord Belzenlok enters, exile cards from the top of your library until you exile a nonland card, then put that card into your hand. If the card's mana value is 4 or greater, repeat this process. Demonlord Belzenlok deals 1 damage to you for each card put into your hand this way.

Graf Reaver

Exploit (When this creature enters, you may sacrifice a creature.)
When Graf Reaver exploits a creature, destroy target planeswalker.
At the beginning of your upkeep, Graf Reaver deals 1 damage to you.

Shadow of Mortality

If your life total is less than your starting life total, this spell costs {X} less to cast, where X is the difference.

Hellish Rebuke

Until end of turn, permanents your opponents control gain "When this permanent deals damage to the player who cast Hellish Rebuke, sacrifice this permanent. You lose 2 life."

Platinum Emperion

Your life total can't change. (You can't gain or lose life. You can't pay any amount of life except 0.)

Kokusho, the Evening Star

Flying
When Kokusho, the Evening Star dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Oath of Lim-Dûl

Whenever you lose life, for each 1 life you lost, sacrifice a permanent other than Oath of Lim-Dûl unless you discard a card. (Damage dealt to you causes you to lose life.)
{B}{B}: Draw a card.

Ashes to Ashes

Exile two target nonartifact creatures. Ashes to Ashes deals 5 damage to you.

Liliana, Waker of the Dead

+1: Each player discards a card. Each opponent who can't loses 3 life.
−3: Target creature gets -X/-X until end of turn, where X is the number of cards in your graveyard.
−7: You get an emblem with "At the beginning of combat on your turn, put target creature card from a graveyard onto the battlefield under your control. It gains haste."

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Swamp

The Golden Throne

Arcane Life-support — If you would lose the game, instead exile The Golden Throne and your life total becomes 1.
A Thousand Souls Die Every Day — {T}, Sacrifice a creature: Add three mana in any combination of colors.