Sign in Blood

Target player draws two cards and loses 2 life.

Infernal Grasp

Destroy target creature. You lose 2 life.

Fatal Push

Destroy target creature if it has mana value 2 or less.
Revolt — Destroy that creature if it has mana value 4 or less instead if a permanent you controlled left the battlefield this turn.

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When Murderous Rider dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Swamp

Knight of the Ebon Legion

{2}{B}: Knight of the Ebon Legion gets +3/+3 and gains deathtouch until end of turn.
At the beginning of your end step, if a player lost 4 or more life this turn, put a +1/+1 counter on Knight of the Ebon Legion. (Damage causes loss of life.)

Tenacious Underdog

Blitz—{2}{B}{B}, Pay 2 life. (If you cast this spell for its blitz cost, it gains haste and "When this creature dies, draw a card." Sacrifice it at the beginning of the next end step.)
You may cast Tenacious Underdog from your graveyard using its blitz ability.

Shadow of Mortality

If your life total is less than your starting life total, this spell costs {X} less to cast, where X is the difference.

Ulcerate

Target creature gets -3/-3 until end of turn. You lose 3 life.

Hive of the Eye Tyrant

If you control two or more other lands, Hive of the Eye Tyrant enters tapped.
{T}: Add {B}.
{3}{B}: Until end of turn, Hive of the Eye Tyrant becomes a 3/3 black Beholder creature with menace and "Whenever this creature attacks, exile target card from defending player's graveyard." It's still a land.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Spawn of Mayhem

Spectacle {1}{B}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Flying, trample
At the beginning of your upkeep, Spawn of Mayhem deals 1 damage to each player. Then if you have 10 or less life, put a +1/+1 counter on Spawn of Mayhem.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Ifnir Deadlands

{T}: Add {C}.
{T}, Pay 1 life: Add {B}.
{2}{B}{B}, {T}, Sacrifice a Desert: Put two -1/-1 counters on target creature an opponent controls. Activate only as a sorcery.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Gix, Yawgmoth Praetor

Whenever a creature deals combat damage to one of your opponents, its controller may pay 1 life. If they do, they draw a card.
{4}{B}{B}{B}, Discard X cards: Exile the top X cards of target opponent's library. You may play lands and cast spells from among cards exiled this way without paying their mana costs.

Misery's Shadow

If a creature an opponent controls would die, exile it instead.
{1}: Misery's Shadow gets +1/+1 until end of turn.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.