Infernal Grasp

Destroy target creature. You lose 2 life.

Ebon Drake

Flying
Whenever a player casts a spell, you lose 1 life.

Doom Blade

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Desecration Elemental

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Whenever a player casts a spell, sacrifice a creature.

Jon Irenicus, Shattered One

At the beginning of your end step, target opponent gains control of up to one target creature you control. Put two +1/+1 counters on it and tap it. It's goaded for the rest of the game and it gains "This creature can't be sacrificed." (It attacks each combat if able and attacks a player other than you if able.)
Whenever a creature you own but don't control attacks, you draw a card.

Rust Elemental

Flying
At the beginning of your upkeep, sacrifice an artifact other than Rust Elemental. If you can't, tap Rust Elemental and you lose 4 life.

Invisible Stalker

Hexproof (This creature can't be the target of spells or abilities your opponents control.)
Invisible Stalker can't be blocked.

Sol Ring

Damnation

Destroy all creatures. They can't be regenerated.

Cancel

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Slither Blade

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Rotting Regisaur

At the beginning of your upkeep, discard a card.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Demonic Taskmaster

Flying
At the beginning of your upkeep, sacrifice a creature other than Demonic Taskmaster.

Tormented Soul

Tormented Soul can't block and can't be blocked.

Changeling Outcast

Changeling (This card is every creature type.)
Changeling Outcast can't block and can't be blocked.

Go for the Throat

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Negate

Necrotic Hex

Each player sacrifices six creatures. You create six tapped 2/2 black Zombie creature tokens.

Lord of the Pit

Flying, trample
At the beginning of your upkeep, sacrifice a creature other than Lord of the Pit. If you can't, Lord of the Pit deals 7 damage to you.

Phyrexian Negator

Trample
Whenever Phyrexian Negator is dealt damage, sacrifice that many permanents.

Midnight Clock

{T}: Add {U}.
{2}{U}: Put an hour counter on Midnight Clock.
At the beginning of each upkeep, put an hour counter on Midnight Clock.
When the twelfth hour counter is put on Midnight Clock, shuffle your hand and graveyard into your library, then draw seven cards. Exile Midnight Clock.

Worn Powerstone

Worn Powerstone enters the battlefield tapped.
{T}: Add {C}{C}.

Choice of Damnations

Target opponent chooses a number. You may have that player lose that much life. If you don't, that player sacrifices all but that many permanents.

Frantic Search

Draw two cards, then discard two cards. Untap up to three lands.

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Serum Visions

Evil Eye of Urborg

Non-Eye creatures you control can't attack.
Whenever Evil Eye of Urborg becomes blocked by a creature, destroy that creature.

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Hero's Downfall

Counterspell

Dimir Signet

Pact of Negation

Counter target spell.
At the beginning of your next upkeep, pay {3}{U}{U}. If you don't, you lose the game.

Prismatic Lens

{T}: Add {C}.
{1}, {T}: Add one mana of any color.

Sudden Substitution

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Exchange control of target noncreature spell and target creature. Then the spell's controller may choose new targets for it.

Consider

Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
Draw a card.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Everflowing Chalice

Multikicker {2} (You may pay an additional {2} any number of times as you cast this spell.)
Everflowing Chalice enters the battlefield with a charge counter on it for each time it was kicked.
{T}: Add {C} for each charge counter on Everflowing Chalice.

Drinker of Sorrow

Drinker of Sorrow can't block.
Whenever Drinker of Sorrow deals combat damage, sacrifice a permanent.