Lord Xander, the Collector

When Lord Xander, the Collector enters, target opponent discards half the cards in their hand, rounded down.
Whenever Lord Xander attacks, defending player mills half their library, rounded down.
When Lord Xander dies, target opponent sacrifices half the nonland permanents they control of their choice, rounded down.

Thraximundar

Haste
Whenever Thraximundar attacks, defending player sacrifices a creature of their choice.
Whenever a player sacrifices a creature, you may put a +1/+1 counter on Thraximundar.

Careful Study

Exhume

Each player puts a creature card from their graveyard onto the battlefield.

Sire of Insanity

At the beginning of each end step, each player discards their hand.

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)