Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Graven Cairns

{T}: Add {C}.
{B/R}, {T}: Add {B}{B}, {B}{R}, or {R}{R}.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Fiery Emancipation

If a source you control would deal damage to a permanent or player, it deals triple that damage to that permanent or player instead.

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Dark Ritual

Shivan Gorge

{T}: Add {C}.
{2}{R}, {T}: Shivan Gorge deals 1 damage to each opponent.

Tymaret, Chosen from Death

Tymaret's toughness is equal to your devotion to black. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
{1}{B}: Exile up to two target cards from graveyards. You gain 1 life for each creature card exiled this way.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Brash Taunter

Indestructible
Whenever Brash Taunter is dealt damage, it deals that much damage to target opponent.
{2}{R}, {T}: Brash Taunter fights another target creature.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Kroxa, Titan of Death's Hunger

When Kroxa enters, sacrifice it unless it escaped.
Whenever Kroxa enters or attacks, each opponent discards a card, then each opponent who didn't discard a nonland card this way loses 3 life.
Escape—{B}{B}{R}{R}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Jet Medallion

Black spells you cast cost {1} less to cast.

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

Sol Ring

Terminate

Destroy target creature. It can't be regenerated.

Kardur, Doomscourge

When Kardur, Doomscourge enters, until your next turn, creatures your opponents control attack each combat if able and attack a player other than you if able.
Whenever an attacking creature dies, each opponent loses 1 life and you gain 1 life.

Mountain

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Swamp

Tectonic Giant

Whenever Tectonic Giant attacks or becomes the target of a spell an opponent controls, choose one —
• Tectonic Giant deals 3 damage to each opponent.
• Exile the top two cards of your library. Choose one of them. Until the end of your next turn, you may play that card.

Plaguecrafter

When Plaguecrafter enters, each player sacrifices a creature or planeswalker of their choice. Each player who can't discards a card.

Infernal Grasp

Destroy target creature. You lose 2 life.

Fabled Passage

{T}, Sacrifice Fabled Passage: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle. Then if you control four or more lands, untap that land.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Sokenzan, Crucible of Defiance

{T}: Add {R}.
Channel — {3}{R}, Discard Sokenzan, Crucible of Defiance: Create two 1/1 colorless Spirit creature tokens. They gain haste until end of turn. This ability costs {1} less to activate for each legendary creature you control.

Hero's Downfall

Haunted Ridge

Haunted Ridge enters tapped unless you control two or more other lands.
{T}: Add {B} or {R}.

Command Tower

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.

Crimson Honor Guard

Trample
At the beginning of each player's end step, Crimson Honor Guard deals 4 damage to that player unless they control a commander.

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Delayed Blast Fireball

Delayed Blast Fireball deals 2 damage to each opponent and each creature they control. If this spell was cast from exile, it deals 5 damage to each opponent and each creature they control instead.
Foretell {4}{R}{R} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Imperial Seal

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Go for the Throat

Balor

Flying
Whenever Balor attacks or dies, choose one or more. Each mode must target a different player.
• Target opponent draws three cards, then discards three cards at random.
• Target opponent sacrifices a nontoken artifact of their choice.
• Balor deals damage to target opponent equal to the number of cards in their hand.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Torbran, Thane of Red Fell

If a red source you control would deal damage to an opponent or a permanent an opponent controls, it deals that much damage plus 2 instead.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Night's Whisper

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. Sulfurous Springs deals 1 damage to you.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Ribbons

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Each opponent loses X life.

Cut // Ribbons

Dreadbore

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Indulgent Tormentor

Flying
At the beginning of your upkeep, draw a card unless target opponent sacrifices a creature of their choice or pays 3 life.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Kederekt Parasite

Whenever an opponent draws a card, if you control a red permanent, you may have Kederekt Parasite deal 1 damage to that player.

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Grafted Exoskeleton

Equipped creature gets +2/+2 and has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Whenever Grafted Exoskeleton becomes unattached from a permanent, sacrifice that permanent.
Equip {2}

Disrupt Decorum

Goad all creatures you don't control. (Until your next turn, those creatures attack each combat if able and attack a player other than you if able.)

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Ruby Medallion

Red spells you cast cost {1} less to cast.

Vandalblast

Destroy target artifact you don't control.
Overload {4}{R} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Ob Nixilis, the Adversary

Casualty X. The copy isn't legendary and has starting loyalty X. (As you cast this spell, you may sacrifice a creature with power X. When you do, copy this spell. The copy becomes a token.)
+1: Each opponent loses 2 life unless they discard a card. If you control a Demon or Devil, you gain 2 life.
−2: Create a 1/1 red Devil creature token with "When this creature dies, it deals 1 damage to any target."
−7: Target player draws seven cards and loses 7 life.

Gix, Yawgmoth Praetor

Whenever a creature deals combat damage to one of your opponents, its controller may pay 1 life. If they do, they draw a card.
{4}{B}{B}{B}, Discard X cards: Exile the top X cards of target opponent's library. You may play lands and cast spells from among cards exiled this way without paying their mana costs.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Red Elemental Blast

Choose one —
• Counter target blue spell.
• Destroy target blue permanent.

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Mayhem Devil

Whenever a player sacrifices a permanent, Mayhem Devil deals 1 damage to any target.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Last One Standing

Choose a creature at random, then destroy the rest.

Hellish Rebuke

Until end of turn, permanents your opponents control gain "When this permanent deals damage to the player who cast Hellish Rebuke, sacrifice this permanent. You lose 2 life."