Pact of Negation

Counter target spell.
At the beginning of your next upkeep, pay {3}{U}{U}. If you don't, you lose the game.

Swan Song

Counter target enchantment, instant, or sorcery spell. Its controller creates a 2/2 blue Bird creature token with flying.

Ravenous Chupacabra

When Ravenous Chupacabra enters, destroy target creature an opponent controls.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Ashiok, Nightmare Muse

+1: Create a 2/3 blue and black Nightmare creature token with "Whenever this creature attacks or blocks, each opponent exiles the top two cards of their library."
−3: Return target nonland permanent to its owner's hand, then that player exiles a card from their hand.
−7: You may cast up to three spells from among face-up cards your opponents own from exile without paying their mana costs.

Tasha's Hideous Laughter

Each opponent exiles cards from the top of their library until that player has exiled cards with total mana value 20 or more.

Counterspell

Umbris, Fear Manifest

Umbris, Fear Manifest gets +1/+1 for each card your opponents own in exile.
Whenever Umbris or another Nightmare or Horror you control enters, target opponent exiles cards from the top of their library until they exile a land card.

Ashiok, Dream Render

Spells and abilities your opponents control can't cause their controller to search their library.
−1: Target player mills four cards. Then exile each opponent's graveyard.

Yarok's Fenlurker

When Yarok's Fenlurker enters, each opponent exiles a card from their hand.
{2}{B}: Yarok's Fenlurker gets +1/+1 until end of turn.

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Mystic Remora

Cumulative upkeep {1} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Whenever an opponent casts a noncreature spell, you may draw a card unless that player pays {4}.