Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Plains

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever this creature attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform this creature and your life total becomes 3. Then if this creature didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Strands of Night

{B}{B}, Pay 2 life, Sacrifice a Swamp: Return target creature card from your graveyard to the battlefield.

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Pact Weapon

As long as this Equipment is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Serra Paragon

Flying
Once during each of your turns, you may play a land from your graveyard or cast a permanent spell with mana value 3 or less from your graveyard. If you do, it gains "When this permanent is put into a graveyard from the battlefield, exile it and you gain 2 life."

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Prismatic Vista

{T}, Pay 1 life, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield, then shuffle.

Sol Ring

Exquisite Archangel

Flying
If you would lose the game, instead exile this creature and your life total becomes equal to your starting life total.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Children of Korlis

Sacrifice this creature: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Soul Warden

Whenever another creature enters, you gain 1 life.

Font of Agonies

Whenever you pay life, put that many blood counters on this enchantment.
{1}{B}, Remove four blood counters from this enchantment: Destroy target creature.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Forsworn Paladin

Menace
{1}{B}, {T}, Pay 1 life: Create a Treasure token.
{2}{B}: Target creature gets +2/+0 until end of turn. If mana from a Treasure was spent to activate this ability, that creature also gains deathtouch until end of turn.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: This artifact deals 50 damage to any target.

Orzhov Signet

Thrull Parasite

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
{T}, Pay 2 life: Remove a counter from target nonland permanent.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Razaketh, the Foulblooded

Flying, trample
Pay 2 life, Sacrifice another creature: Search your library for a card, put that card into your hand, then shuffle.

Despark

Exile target permanent with mana value 4 or greater.

Verrak, Warped Sengir

Flying, deathtouch, lifelink
Whenever you activate an ability that isn't a mana ability, if life was paid to activate it, you may pay that much life again. If you do, copy that ability. You may choose new targets for the copy.

Bloodtracker

Flying
{B}, Pay 2 life: Put a +1/+1 counter on this creature.
When this creature leaves the battlefield, draw a card for each +1/+1 counter on it.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Marsh Flats

{T}, Pay 1 life, Sacrifice this land: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Mortarion, Daemon Primarch

Flying
Primarch of the Death Guard — At the beginning of your end step, you may pay {X}. If you do, create X 2/2 black Astartes Warrior creature tokens with menace. X can't be greater than the amount of life you lost this turn.

Generous Gift

Destroy target permanent. Its controller creates a 3/3 green Elephant creature token.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Glass-Cast Heart

Whenever one or more Vampires you control attack, create a Blood token. (It's an artifact with "{1}, {T}, Discard a card, Sacrifice this token: Draw a card.")
{B}, {T}, Pay 1 life: Create a 1/1 white and black Vampire creature token with lifelink.
{B}{B}, {T}, Sacrifice this artifact and thirteen Blood tokens: Each opponent loses 13 life and you gain 13 life.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Tainted Sigil

{T}, Sacrifice this artifact: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Eternity Vessel

This artifact enters with X charge counters on it, where X is your life total.
Landfall — Whenever a land you control enters, you may have your life total become the number of charge counters on this artifact.

Priest of Fell Rites

{T}, Pay 3 life, Sacrifice this creature: Return target creature card from your graveyard to the battlefield. Activate only as a sorcery.
Unearth {3}{W}{B} ({3}{W}{B}: Return this card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step or if it would leave the battlefield. Unearth only as a sorcery.)

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, this creature gets +5/+5 and has flying.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Cloudsteel Kirin

Flying
Equipped creature has flying and "You can't lose the game and your opponents can't win the game."
Reconfigure {5} ({5}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Greed

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Crucible of Worlds

Swamp

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Street Wraith

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
Cycling—Pay 2 life. (Pay 2 life, Discard this card: Draw a card.)

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Godless Shrine

({T}: Add {W} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Chainer, Dementia Master

All Nightmares get +1/+1.
{B}{B}{B}, Pay 3 life: Put target creature card from a graveyard onto the battlefield under your control. That creature is black and is a Nightmare in addition to its other creature types.
When Chainer leaves the battlefield, exile all Nightmares.