Vona's Hunger

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
Each opponent sacrifices a creature of their choice. If you have the city's blessing, instead each opponent sacrifices half the creatures they control of their choice, rounded up.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Infernal Darkness

Cumulative upkeep—Pay {B} and 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
If a land is tapped for mana, it produces {B} instead of any other type.

Hymn to Tourach

Target player discards two cards at random.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Death Cloud

Each player loses X life, discards X cards, sacrifices X creatures of their choice, then sacrifices X lands of their choice.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Contamination

At the beginning of your upkeep, sacrifice Contamination unless you sacrifice a creature.
If a land is tapped for mana, it produces {B} instead of any other type and amount.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Desolation

At the beginning of each end step, each player who tapped a land for mana this turn sacrifices a land of their choice. Desolation deals 2 damage to each player who sacrificed a Plains this way.

Make an Example

Each opponent separates the creatures they control into two piles. For each opponent, you choose one of their piles. Each opponent sacrifices the creatures in their chosen pile. (Piles can be empty.)

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Swamp

Mire in Misery

Each opponent sacrifices a creature or enchantment of their choice.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Sol Ring

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Braids, Arisen Nightmare

At the beginning of your end step, you may sacrifice an artifact, creature, enchantment, land, or planeswalker. If you do, each opponent may sacrifice a permanent of their choice that shares a card type with it. For each opponent who doesn't, that player loses 2 life and you draw a card.

Gix's Command

Choose two —
• Put two +1/+1 counters on up to one creature. It gains lifelink until end of turn.
• Destroy each creature with power 2 or less.
• Return up to two creature cards from your graveyard to your hand.
• Each opponent sacrifices a creature with the highest power among creatures they control.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Smokestack

At the beginning of your upkeep, you may put a soot counter on Smokestack.
At the beginning of each player's upkeep, that player sacrifices a permanent of their choice for each soot counter on Smokestack.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Hellish Rebuke

Until end of turn, permanents your opponents control gain "When this permanent deals damage to the player who cast Hellish Rebuke, sacrifice this permanent. You lose 2 life."

Portal to Phyrexia

When Portal to Phyrexia enters, each opponent sacrifices three creatures of their choice.
At the beginning of your upkeep, put target creature card from a graveyard onto the battlefield under your control. It's a Phyrexian in addition to its other types.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Ill-Gotten Gains

Exile Ill-Gotten Gains. Each player discards their hand, then returns up to three cards from their graveyard to their hand.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Sadistic Hypnotist

Sacrifice a creature: Target player discards two cards. Activate only as a sorcery.

Rankle, Master of Pranks

Flying, haste
Whenever Rankle, Master of Pranks deals combat damage to a player, choose any number —
• Each player discards a card.
• Each player loses 1 life and draws a card.
• Each player sacrifices a creature of their choice.

Oppression

Whenever a player casts a spell, that player discards a card.

Bubbling Muck

Until end of turn, whenever a player taps a Swamp for mana, that player adds an additional {B}.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Innocent Blood

Each player sacrifices a creature of their choice.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Tragic Slip

Target creature gets -1/-1 until end of turn.
Morbid — That creature gets -13/-13 until end of turn instead if a creature died this turn.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Junji, the Midnight Sky

Flying, menace
When Junji, the Midnight Sky dies, choose one —
• Each opponent discards two cards and loses 2 life.
• Put target non-Dragon creature card from a graveyard onto the battlefield under your control. You lose 2 life.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Mindslicer

When Mindslicer dies, each player discards their hand.

Delirium Skeins

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Grave Pact

Whenever a creature you control dies, each other player sacrifices a creature of their choice.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Words of Waste

{1}: The next time you would draw a card this turn, each opponent discards a card instead.

Gibbering Descent

At the beginning of each player's upkeep, that player loses 1 life and discards a card.
Hellbent — Skip your upkeep step if you have no cards in hand.
Madness {2}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature of their choice.

Dark Ritual

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Cruel Tutor

Soul Shatter

Each opponent sacrifices a creature or planeswalker with the highest mana value among creatures and planeswalkers they control.