Avacyn, the Purifier

Flying
When this creature transforms into Avacyn, the Purifier, it deals 3 damage to each other creature and each opponent.

Archangel Avacyn

Flash
Flying, vigilance
When Archangel Avacyn enters, creatures you control gain indestructible until end of turn.
When a non-Angel creature you control dies, transform Archangel Avacyn at the beginning of the next upkeep.

Archangel Avacyn // Avacyn, the Purifier

Aurora of Emrakul

Flying, deathtouch
Whenever this creature attacks, each opponent loses 3 life.

Cryptolith Fragment

This artifact enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform this artifact.

Cryptolith Fragment // Aurora of Emrakul

Aria of Flame

When this enchantment enters, each opponent gains 10 life.
Whenever you cast an instant or sorcery spell, put a verse counter on this enchantment, then it deals damage equal to the number of verse counters on it to target player or planeswalker.

Braids's Frightful Return

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — You may sacrifice a creature. If you do, each opponent discards a card.
II — Return target creature card from your graveyard to your hand.
III — Target opponent may sacrifice a nonland, nontoken permanent of their choice. If they don't, they lose 2 life and you draw a card.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Bubbling Cauldron

{1}, {T}, Sacrifice a creature: You gain 4 life.
{1}, {T}, Sacrifice a creature named Festering Newt: Each opponent loses 4 life. You gain life equal to the life lost this way.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Altar of the Brood

Whenever another permanent you control enters, each opponent mills a card.

Burglar Rat

When this creature enters, each opponent discards a card.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip this creature.

Nezumi Shortfang // Stabwhisker the Odious

Ayara, First of Locthwain

Whenever Ayara or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Tormented Hero

This creature enters tapped.
Heroic — Whenever you cast a spell that targets this creature, each opponent loses 1 life. You gain life equal to the life lost this way.

Night Market Lookout

Whenever this creature becomes tapped, each opponent loses 1 life and you gain 1 life.

Serrated Scorpion

When this creature dies, it deals 2 damage to each opponent and you gain 2 life.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Gnat Miser

Each opponent's maximum hand size is reduced by one.

Angelic Arbiter

Flying
Each opponent who cast a spell this turn can't attack with creatures.
Each opponent who attacked with a creature this turn can't cast spells.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Echo of Death's Wail

Flying, haste
When this creature enters, gain control of all Rat tokens.
Whenever this creature attacks, you may sacrifice another creature. If you do, draw a card.

Tribute to Horobi

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent creates a 1/1 black Rat Rogue creature token.
III — Exile this Saga, then return it to the battlefield transformed under your control.

Tribute to Horobi // Echo of Death's Wail

Leechridden Swamp

({T}: Add {B}.)
This land enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Throne of the God-Pharaoh

At the beginning of your end step, each opponent loses life equal to the number of tapped creatures you control.

Tattered Mummy

When this creature dies, each opponent loses 2 life.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Virus Beetle

Ashiok's Adept

Heroic — Whenever you cast a spell that targets this creature, each opponent discards a card.

Bontu the Glorified

Menace, indestructible
Bontu can't attack or block unless a creature died under your control this turn.
{1}{B}, Sacrifice another creature: Scry 1. Each opponent loses 1 life and you gain 1 life.

Pulse Tracker

Whenever this creature attacks, each opponent loses 1 life.

Bastion of Remembrance

When this enchantment enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Thieves' Guild Enforcer

Flash
Whenever this creature or another Rogue you control enters, each opponent mills two cards.
As long as an opponent has eight or more cards in their graveyard, this creature gets +2/+1 and has deathtouch.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on this enchantment.
At the beginning of each opponent's upkeep, if that player has no cards in hand and this enchantment has two or more quest counters on it, you may have that player lose 5 life.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.