Despark

Exile target permanent with mana value 4 or greater.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Command the Dreadhorde

Choose any number of target creature and/or planeswalker cards in graveyards. Command the Dreadhorde deals damage to you equal to the total mana value of those cards. Put them onto the battlefield under your control.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Inkshield

Prevent all combat damage that would be dealt to you this turn. For each 1 damage prevented this way, create a 2/1 white and black Inkling creature token with flying.

Ambition's Cost

You draw three cards and you lose 3 life.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Forever Young

Put any number of target creature cards from your graveyard on top of your library.
Draw a card.

Infernal Grasp

Destroy target creature. You lose 2 life.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Ancient Craving

Light of Promise

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

Night's Whisper

Boon Reflection

If you would gain life, you gain twice that much life instead.

Moonlight Bargain

Look at the top five cards of your library. For each card, put that card into your graveyard unless you pay 2 life. Then put the rest into your hand.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Court of Ambition

When Court of Ambition enters the battlefield, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Voice of the Blessed

Whenever you gain life, put a +1/+1 counter on Voice of the Blessed.
As long as Voice of the Blessed has four or more +1/+1 counters on it, it has flying and vigilance.
As long as Voice of the Blessed has ten or more +1/+1 counters on it, it has indestructible.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Death Grasp

Death Grasp deals X damage to any target. You gain X life.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Marchesa's Decree

When Marchesa's Decree enters the battlefield, you become the monarch.
Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Sign in Blood

Target player draws two cards and loses 2 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Sphere of Safety

Creatures can't attack you or planeswalkers you control unless their controller pays {X} for each of those creatures, where X is the number of enchantments you control.

Foreboding Fruit

Target player draws two cards and loses 2 life.
Adamant — If at least three black mana was spent to cast this spell, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")