Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Mikokoro, Center of the Sea

{T}: Add {C}.
{2}, {T}: Each player draws a card.

Dictate of Kruphix

Flash
At the beginning of each player's draw step, that player draws an additional card.

Duskmantle Guildmage

{1}{U}{B}: Whenever a card is put into an opponent's graveyard from anywhere this turn, that player loses 1 life.
{2}{U}{B}: Target player mills two cards.

Reality Shift

Exile target creature. Its controller manifests the top card of their library. (That player puts the top card of their library onto the battlefield face down as a 2/2 creature. If it's a creature card, it can be turned face up any time for its mana cost.)

The Raven Man

At the beginning of each end step, if a player discarded a card this turn, create a 1/1 black Bird creature token with flying and "This creature can't block."
{3}{B}, {T}: Each opponent discards a card. Activate only as a sorcery.

Sol Ring

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Jace's Archivist

{U}, {T}: Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Undermine

Counter target spell. Its controller loses 3 life.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent or discard a card.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Whispering Madness

Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Recoil

Return target permanent to its owner's hand. Then that player discards a card.

Scythe Specter

Flying
Whenever Scythe Specter deals combat damage to a player, each opponent discards a card. Each player who discarded a card with the highest mana value among cards discarded this way loses life equal to that mana value.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Kami of the Crescent Moon

At the beginning of each player's draw step, that player draws an additional card.

Vision Skeins

Liliana, Waker of the Dead

+1: Each player discards a card. Each opponent who can't loses 3 life.
−3: Target creature gets -X/-X until end of turn, where X is the number of cards in your graveyard.
−7: You get an emblem with "At the beginning of combat on your turn, put target creature card from a graveyard onto the battlefield under your control. It gains haste."

Drown in the Loch

Choose one —
• Counter target spell with mana value less than or equal to the number of cards in its controller's graveyard.
• Destroy target creature with mana value less than or equal to the number of cards in its controller's graveyard.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Abyssal Nocturnus

Whenever an opponent discards a card, Abyssal Nocturnus gets +2/+2 and gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Duskmantle Seer

Flying
At the beginning of your upkeep, each player reveals the top card of their library, loses life equal to that card's mana value, then puts it into their hand.

Lore Broker

{T}: Each player draws a card, then discards a card.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Phyrexian Espionage

Kicker {1}{B} (You may pay an additional {1}{B} as you cast this spell.)
Draw two cards. If this spell was kicked, each opponent discards a card.

Soul Barrier

Whenever an opponent casts a creature spell, Soul Barrier deals 2 damage to that player unless they pay {2}.

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Dimir Signet

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Vile Consumption

All creatures have "At the beginning of your upkeep, sacrifice this creature unless you pay 1 life."

Minds Aglow

Join forces — Starting with you, each player may pay any amount of mana. Each player draws X cards, where X is the total amount of mana paid this way.

Island

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Retreat to Hagra

Landfall — Whenever a land you control enters, choose one —
• Target creature gets +1/+0 and gains deathtouch until end of turn.
• Each opponent loses 1 life and you gain 1 life.

Counterspell

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Mage Hunter

Whenever an opponent casts or copies an instant or sorcery spell, they lose 1 life.

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Nightshade Harvester

Whenever a land an opponent controls enters, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Swamp

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Command Tower

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Notion Thief

Flash
If an opponent would draw a card except the first one they draw in each of their draw steps, instead that player skips that draw and you draw a card.

Perplex

Counter target spell unless its controller discards their hand.
Transmute {1}{U}{B} ({1}{U}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Dream Salvage

Draw cards equal to the number of cards target opponent discarded this turn.

Ankh of Mishra

Whenever a land enters, Ankh of Mishra deals 2 damage to that land's controller.

Doomsday Specter

Flying
When Doomsday Specter enters, return a blue or black creature you control to its owner's hand.
Whenever Doomsday Specter deals combat damage to a player, look at that player's hand and choose a card from it. The player discards that card.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Countersquall

Counter target noncreature spell. Its controller loses 2 life.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Otherworld Atlas

{T}: Put a charge counter on Otherworld Atlas.
{T}: Each player draws a card for each charge counter on Otherworld Atlas.

Reliquary Tower

Urza's Guilt

Each player draws two cards, then discards three cards, then loses 4 life.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.