Iridian Maelstrom

Destroy each creature that isn't all colors.

Granulate

Destroy each nonland artifact with mana value 4 or less.

Engineered Explosives

Sunburst (This enters with a charge counter on it for each color of mana spent to cast it.)
{2}, Sacrifice Engineered Explosives: Destroy each nonland permanent with mana value equal to the number of charge counters on Engineered Explosives.

Plague Wind

Destroy all creatures you don't control. They can't be regenerated.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

End Hostilities

Destroy all creatures and all permanents attached to creatures.

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Duneblast

Choose up to one creature. Destroy the rest.

Gaze of Granite

Destroy each nonland permanent with mana value X or less.

Back to Nature

Blood Money

Destroy all creatures. For each nontoken creature destroyed this way, you create a tapped Treasure token.

Devastating Mastery

You may pay {2}{W}{W} rather than pay this spell's mana cost.
If the {2}{W}{W} cost was paid, an opponent chooses up to two nonland permanents they control and returns them to their owner's hand.
Destroy all nonland permanents.

Fated Retribution

Destroy all creatures and planeswalkers. If it's your turn, scry 2.

Blood on the Snow

Choose one —
• Destroy all creatures.
• Destroy all planeswalkers.
Then return a creature or planeswalker card with mana value X or less from your graveyard to the battlefield, where X is the amount of {S} spent to cast this spell. ({S} is mana from a snow source.)

Divine Reckoning

Each player chooses a creature they control. Destroy the rest.
Flashback {5}{W}{W} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Creeping Corrosion

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Armageddon

Casualties of War

Choose one or more —
• Destroy target artifact.
• Destroy target creature.
• Destroy target enchantment.
• Destroy target land.
• Destroy target planeswalker.

Extinguish All Hope

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Elspeth, Sun's Champion

+1: Create three 1/1 white Soldier creature tokens.
−3: Destroy all creatures with power 4 or greater.
−7: You get an emblem with "Creatures you control get +2/+2 and have flying."

Day of Judgment

Damnation

Destroy all creatures. They can't be regenerated.

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Karn's Sylex

Karn's Sylex enters tapped.
Players can't pay life to cast spells or to activate abilities that aren't mana abilities.
{X}, {T}, Exile Karn's Sylex: Destroy each nonland permanent with mana value X or less. Activate only as a sorcery.

Paraselene

Destroy all enchantments. You gain 1 life for each enchantment destroyed this way.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Planar Cleansing

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Cleanfall

Novablast Wurm

Whenever Novablast Wurm attacks, destroy all other creatures.

Kindred Dominance

Choose a creature type. Destroy all creatures that aren't of the chosen type.

Damning Verdict

Destroy all creatures with no counters on them.

Fracturing Gust

Destroy all artifacts and enchantments. You gain 2 life for each permanent destroyed this way.