Pact of Negation

Counter target spell.
At the beginning of your next upkeep, pay {3}{U}{U}. If you don't, you lose the game.

Force of Negation

If it's not your turn, you may exile a blue card from your hand rather than pay this spell's mana cost.
Counter target noncreature spell. If that spell is countered this way, exile it instead of putting it into its owner's graveyard.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. Talisman of Hierarchy deals 1 damage to you.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Badlands

Snow-Covered Mountain

Xander's Lounge

({T}: Add {U}, {B}, or {R}.)
Xander's Lounge enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Ketria Triome

({T}: Add {G}, {U}, or {R}.)
Ketria Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Talisman of Impulse

{T}: Add {C}.
{T}: Add {R} or {G}. Talisman of Impulse deals 1 damage to you.

Bayou

Thassa, God of the Sea

Indestructible
As long as your devotion to blue is less than five, Thassa isn't a creature. (Each {U} in the mana costs of permanents you control counts toward your devotion to blue.)
At the beginning of your upkeep, scry 1.
{1}{U}: Target creature you control can't be blocked this turn.

Talisman of Conviction

{T}: Add {C}.
{T}: Add {R} or {W}. Talisman of Conviction deals 1 damage to you.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Wooded Foothills

{T}, Pay 1 life, Sacrifice Wooded Foothills: Search your library for a Mountain or Forest card, put it onto the battlefield, then shuffle.

Resolute Watchdog

Defender
{1}, Sacrifice Resolute Watchdog: Target creature you control gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Plateau

Arid Mesa

{T}, Pay 1 life, Sacrifice Arid Mesa: Search your library for a Mountain or Plains card, put it onto the battlefield, then shuffle.

Talisman of Creativity

{T}: Add {C}.
{T}: Add {U} or {R}. Talisman of Creativity deals 1 damage to you.

Force of Will

You may pay 1 life and exile a blue card from your hand rather than pay this spell's mana cost.
Counter target spell.

Predator Ooze

Indestructible (Damage and effects that say "destroy" don't destroy this creature.)
Whenever this creature attacks, put a +1/+1 counter on it.
Whenever a creature dealt damage by this creature this turn dies, put a +1/+1 counter on this creature.

Ziatora's Proving Ground

({T}: Add {B}, {R}, or {G}.)
Ziatora's Proving Ground enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Talisman of Unity

{T}: Add {C}.
{T}: Add {G} or {W}. Talisman of Unity deals 1 damage to you.

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Frontline Medic

Battalion — Whenever Frontline Medic and at least two other creatures attack, creatures you control gain indestructible until end of turn.
Sacrifice Frontline Medic: Counter target spell with {X} in its mana cost unless its controller pays {3}.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Snow-Covered Swamp

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Indatha Triome

({T}: Add {W}, {B}, or {G}.)
Indatha Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Talisman of Curiosity

{T}: Add {C}.
{T}: Add {G} or {U}. Talisman of Curiosity deals 1 damage to you.

Taiga

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Rhonas the Indomitable

Deathtouch, indestructible
Rhonas the Indomitable can't attack or block unless you control another creature with power 4 or greater.
{2}{G}: Another target creature gets +2/+0 and gains trample until end of turn.

Talisman of Progress

{T}: Add {C}.
{T}: Add {W} or {U}. Talisman of Progress deals 1 damage to you.

Selfless Savior

Sacrifice Selfless Savior: Another target creature you control gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Misty Rainforest

{T}, Pay 1 life, Sacrifice Misty Rainforest: Search your library for a Forest or Island card, put it onto the battlefield, then shuffle.

Klothys, God of Destiny

Indestructible
As long as your devotion to red and green is less than seven, Klothys isn't a creature.
At the beginning of your first main phase, exile target card from a graveyard. If it was a land card, add {R} or {G}. Otherwise, you gain 2 life and Klothys deals 2 damage to each opponent.

Athreos, God of Passage

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
Whenever another creature you own dies, return it to your hand unless target opponent pays 3 life.

Kefnet the Mindful

Flying, indestructible
Kefnet the Mindful can't attack or block unless you have seven or more cards in hand.
{3}{U}: Draw a card, then you may return a land you control to its owner's hand.

Snow-Covered Forest

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Wrath of God

Destroy all creatures. They can't be regenerated.

Damnation

Talisman of Resilience

{T}: Add {C}.
{T}: Add {B} or {G}. Talisman of Resilience deals 1 damage to you.

Novablast Wurm

Whenever Novablast Wurm attacks, destroy all other creatures.

Tyr's Blessing

Target creature gains indestructible until end of turn. (Then exile this card. You may cast the creature later from exile.)

Blessed Hippogriff

Flying
Whenever Blessed Hippogriff attacks, target attacking creature without flying gains flying until end of turn.

Blessed Hippogriff // Tyr's Blessing

Scry 1. (Look at the top card of your library. You may put that card on the bottom.)
Draw a card.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Jetmir's Garden

({T}: Add {R}, {G}, or {W}.)
Jetmir's Garden enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Spara's Headquarters

({T}: Add {G}, {W}, or {U}.)
Spara's Headquarters enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Scrubland

Planar Cleansing

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Pharika, God of Affliction

Indestructible
As long as your devotion to black and green is less than seven, Pharika isn't a creature.
{B}{G}: Exile target creature card from a graveyard. Its owner creates a 1/1 black and green Snake enchantment creature token with deathtouch.

Zagoth Triome

({T}: Add {B}, {G}, or {U}.)
Zagoth Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Counterspell

Savai Triome

({T}: Add {R}, {W}, or {B}.)
Savai Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Bronzehide Lion

{G}{W}: Bronzehide Lion gains indestructible until end of turn.
When Bronzehide Lion dies, return it to the battlefield. It's an Aura enchantment with enchant creature you control and "{G}{W}: Enchanted creature gains indestructible until end of turn," and it loses all other abilities.

Sol Ring

Windswept Heath

{T}, Pay 1 life, Sacrifice Windswept Heath: Search your library for a Forest or Plains card, put it onto the battlefield, then shuffle.

Day of Judgment

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Gideon, Battle-Forged

+2: Up to one target creature an opponent controls attacks Gideon, Battle-Forged during its controller's next turn if able.
+1: Until your next turn, target creature gains indestructible. Untap that creature.
0: Until end of turn, Gideon, Battle-Forged becomes a 4/4 Human Soldier creature with indestructible that's still a planeswalker. Prevent all damage that would be dealt to him this turn.

Kytheon, Hero of Akros

At end of combat, if Kytheon, Hero of Akros and at least two other creatures attacked this combat, exile Kytheon, then return him to the battlefield transformed under his owner's control.
{2}{W}: Kytheon gains indestructible until end of turn.

Kytheon, Hero of Akros // Gideon, Battle-Forged

Scalding Tarn

{T}, Pay 1 life, Sacrifice Scalding Tarn: Search your library for an Island or Mountain card, put it onto the battlefield, then shuffle.

Linvala, Shield of Sea Gate

Flying
At the beginning of combat on your turn, if you have a full party, choose target nonland permanent an opponent controls. Until your next turn, it can't attack or block, and its activated abilities can't be activated.
Sacrifice Linvala: Choose hexproof or indestructible. Creatures you control gain that ability until end of turn.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Dauntless Escort

Sacrifice Dauntless Escort: Creatures you control gain indestructible until end of turn.

Raffine's Tower

({T}: Add {W}, {U}, or {B}.)
Raffine's Tower enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Darksteel Reactor

Indestructible (Effects that say "destroy" don't destroy this artifact.)
At the beginning of your upkeep, you may put a charge counter on Darksteel Reactor.
When Darksteel Reactor has twenty or more charge counters on it, you win the game.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Selfless Samurai

Whenever a Samurai or Warrior you control attacks alone, it gains lifelink until end of turn.
Sacrifice Selfless Samurai: Another target creature you control gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Deadly Vanity

Choose a creature or planeswalker, then destroy all other creatures and planeswalkers.

Selfless Glyphweaver

Exile Selfless Glyphweaver: Creatures you control gain indestructible until end of turn.

Selfless Glyphweaver // Deadly Vanity

Fleecemane Lion

{3}{G}{W}: Monstrosity 1. (If this creature isn't monstrous, put a +1/+1 counter on it and it becomes monstrous.)
As long as Fleecemane Lion is monstrous, it has hexproof and indestructible.

Selfless Spirit

Flying
Sacrifice Selfless Spirit: Creatures you control gain indestructible until end of turn.

Tundra

Savannah

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Volcanic Island

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Nevinyrral, Urborg Tyrant

Hexproof from artifacts, creatures, and enchantments
When Nevinyrral, Urborg Tyrant enters, create a tapped 2/2 black Zombie creature token for each creature that died this turn.
When Nevinyrral dies, you may pay {1}. When you do, destroy all artifacts, creatures, and enchantments.

Verdant Catacombs

{T}, Pay 1 life, Sacrifice Verdant Catacombs: Search your library for a Swamp or Forest card, put it onto the battlefield, then shuffle.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Underground Sea

Snow-Covered Island

Raugrin Triome

({T}: Add {U}, {R}, or {W}.)
Raugrin Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Transcendent Master

Level up {1} ({1}: Put a level counter on this. Level up only as a sorcery.)
LEVEL 6-11
6/6
Lifelink
LEVEL 12+
9/9
Lifelink, indestructible

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Sparkhunter Masticore

As an additional cost to cast this spell, discard a card.
Protection from planeswalkers
{1}: Sparkhunter Masticore deals 1 damage to target planeswalker.
{3}: Sparkhunter Masticore gains indestructible until end of turn.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. Talisman of Indulgence deals 1 damage to you.