Laboratory Maniac

If you would draw a card while your library has no cards in it, you win the game instead.

Imperial Seal

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Culling the Weak

As an additional cost to cast this spell, sacrifice a creature.
Add {B}{B}{B}{B}.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Island

Cabal Ritual

Add {B}{B}{B}.
Threshold — Add {B}{B}{B}{B}{B} instead if seven or more cards are in your graveyard.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Mystic Remora

Cumulative upkeep {1} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Whenever an opponent casts a noncreature spell, you may draw a card unless that player pays {4}.

Vohar, Vodalian Desecrator

{T}: Draw a card, then discard a card. If you discarded an instant or sorcery card this way, each opponent loses 1 life and you gain 1 life.
{2}, Sacrifice Vohar, Vodalian Desecrator: You may cast target instant or sorcery card from your graveyard this turn. If that spell would be put into your graveyard, exile it instead. Activate only as a sorcery.

Thought Scour

Target player mills two cards.
Draw a card.

Snow-Covered Island

Scalding Tarn

{T}, Pay 1 life, Sacrifice Scalding Tarn: Search your library for an Island or Mountain card, put it onto the battlefield, then shuffle.

Snow-Covered Swamp

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Misdirection

You may exile a blue card from your hand rather than pay this spell's mana cost.
Change the target of target spell with a single target.

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Dark Ritual

Mindbreak Trap

If an opponent cast three or more spells this turn, you may pay {0} rather than pay this spell's mana cost.
Exile any number of target spells.

Mask of the Mimic

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a card with the same name as target nontoken creature, put that card onto the battlefield, then shuffle.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Cephalid Coliseum

{T}: Add {U}. Cephalid Coliseum deals 1 damage to you.
Threshold — {U}, {T}, Sacrifice Cephalid Coliseum: Target player draws three cards, then discards three cards. Activate only if seven or more cards are in your graveyard.

Darkslick Shores

Darkslick Shores enters tapped unless you control two or fewer other lands.
{T}: Add {U} or {B}.

Gitaxian Probe

({U/P} can be paid with either {U} or 2 life.)
Look at target player's hand.
Draw a card.

Lotus Petal

{T}, Sacrifice Lotus Petal: Add one mana of any color.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. Underground River deals 1 damage to you.

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Isochron Scepter

Imprint — When Isochron Scepter enters, you may exile an instant card with mana value 2 or less from your hand.
{2}, {T}: You may copy the exiled card. If you do, you may cast the copy without paying its mana cost.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Mnemonic Betrayal

Exile all opponents' graveyards. You may cast spells from among those cards this turn, and mana of any type can be spent to cast them. At the beginning of the next end step, if any of those cards remain exiled, return them to their owners' graveyards.
Exile Mnemonic Betrayal.

Mental Misstep

({U/P} can be paid with either {U} or 2 life.)
Counter target spell with mana value 1.

Chain of Vapor

Return target nonland permanent to its owner's hand. Then that permanent's controller may sacrifice a land of their choice. If the player does, they may copy this spell and may choose a new target for that copy.

Spire of Industry

{T}: Add {C}.
{T}, Pay 1 life: Add one mana of any color. Activate only if you control an artifact.

Sol Ring

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Swan Song

Counter target enchantment, instant, or sorcery spell. Its controller creates a 2/2 blue Bird creature token with flying.

Fierce Guardianship

If you control a commander, you may cast this spell without paying its mana cost.
Counter target noncreature spell.

Spellseeker

When Spellseeker enters, you may search your library for an instant or sorcery card with mana value 2 or less, reveal it, put it into your hand, then shuffle.

Narset, Parter of Veils

Each opponent can't draw more than one card each turn.
−2: Look at the top four cards of your library. You may reveal a noncreature, nonland card from among them and put it into your hand. Put the rest on the bottom of your library in a random order.

Shallow Grave

Return the top creature card of your graveyard to the battlefield. That creature gains haste until end of turn. Exile it at the beginning of the next end step.

Praetor's Grasp

Search target opponent's library for a card and exile it face down. Then that player shuffles. You may play that card for as long as it remains exiled.

Morphic Pool

Morphic Pool enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Jeweled Lotus

{T}, Sacrifice Jeweled Lotus: Add three mana of any one color. Spend this mana only to cast your commander.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Otawara, Soaring City

{T}: Add {U}.
Channel — {3}{U}, Discard Otawara, Soaring City: Return target artifact, creature, enchantment, or planeswalker to its owner's hand. This ability costs {1} less to activate for each legendary creature you control.

Springleaf Drum

{T}, Tap an untapped creature you control: Add one mana of any color.

Personal Tutor

Search your library for a sorcery card, reveal it, then shuffle and put that card on top.

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Dramatic Reversal

Untap all nonland permanents you control.

Underground Sea

Grim Monolith

Grim Monolith doesn't untap during your untap step.
{T}: Add {C}{C}{C}.
{4}: Untap Grim Monolith.

Gemstone Caverns

If Gemstone Caverns is in your opening hand and you're not the starting player, you may begin the game with Gemstone Caverns on the battlefield with a luck counter on it. If you do, exile a card from your hand.
{T}: Add {C}. If Gemstone Caverns has a luck counter on it, instead add one mana of any color.

Demonic Consultation

Choose a card name. Exile the top six cards of your library, then reveal cards from the top of your library until you reveal a card with the chosen name. Put that card into your hand and exile all other cards revealed this way.

Dimir Signet

March of Swirling Mist

As an additional cost to cast this spell, you may exile any number of blue cards from your hand. This spell costs {2} less to cast for each card exiled this way.
Up to X target creatures phase out. (While they're phased out, they're treated as though they don't exist. Each one phases in before its controller untaps during their next untap step.)

Unearth

Return target creature card with mana value 3 or less from your graveyard to the battlefield.
Cycling {2} ({2}, Discard this card: Draw a card.)

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Swamp

Entomb

Search your library for a card, put that card into your graveyard, then shuffle.

Phantasmal Image

You may have Phantasmal Image enter as a copy of any creature on the battlefield, except it's an Illusion in addition to its other types and it has "When this creature becomes the target of a spell or ability, sacrifice it."

Force of Will

You may pay 1 life and exile a blue card from your hand rather than pay this spell's mana cost.
Counter target spell.

Misty Rainforest

{T}, Pay 1 life, Sacrifice Misty Rainforest: Search your library for a Forest or Island card, put it onto the battlefield, then shuffle.

Animate Dead

Enchant creature card in a graveyard
When Animate Dead enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Animate Dead." Return enchanted creature card to the battlefield under your control and attach Animate Dead to it. When Animate Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Muddle the Mixture

Counter target instant or sorcery spell.
Transmute {1}{U}{U} ({1}{U}{U}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Defense Grid

Each spell costs {3} more to cast except during its controller's turn.

Chrome Mox

Imprint — When Chrome Mox enters, you may exile a nonartifact, nonland card from your hand.
{T}: Add one mana of any of the exiled card's colors.

Cut Down

Destroy target creature with total power and toughness 5 or less.

Benevolent Geist

Flying
Noncreature spells you control can't be countered.
If Benevolent Geist would be put into a graveyard from anywhere, exile it instead.

Malevolent Hermit

{U}, Sacrifice Malevolent Hermit: Counter target noncreature spell unless its controller pays {3}.
Disturb {2}{U} (You may cast this card from your graveyard transformed for its disturb cost.)

Malevolent Hermit // Benevolent Geist

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Plaza of Heroes

{T}: Add {C}.
{T}: Add one mana of any color. Spend this mana only to cast a legendary spell.
{T}: Add one mana of any color among legendary permanents you control.
{3}, {T}, Exile Plaza of Heroes: Target legendary creature gains hexproof and indestructible until end of turn.

Pact of Negation

Counter target spell.
At the beginning of your next upkeep, pay {3}{U}{U}. If you don't, you lose the game.

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Jace, Wielder of Mysteries

If you would draw a card while your library has no cards in it, you win the game instead.
+1: Target player mills two cards. Draw a card.
−8: Draw seven cards. Then if your library has no cards in it, you win the game.

Windfall

Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Mana Vault

Mana Vault doesn't untap during your untap step.
At the beginning of your upkeep, you may pay {4}. If you do, untap Mana Vault.
At the beginning of your draw step, if Mana Vault is tapped, it deals 1 damage to you.
{T}: Add {C}{C}{C}.

Command Tower

Mox Opal

Metalcraft — {T}: Add one mana of any color. Activate only if you control three or more artifacts.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. Talisman of Dominance deals 1 damage to you.

Lim-Dûl's Vault

Look at the top five cards of your library. As many times as you choose, you may pay 1 life, put those cards on the bottom of your library in any order, then look at the top five cards of your library. Then shuffle and put the last cards you looked at this way on top in any order.

Wishclaw Talisman

This artifact enters with three wish counters on it.
{1}, {T}, Remove a wish counter from this artifact: Search your library for a card, put it into your hand, then shuffle. An opponent gains control of this artifact. Activate only during your turn.

Tainted Pact

Exile the top card of your library. You may put that card into your hand unless it has the same name as another card exiled this way. Repeat this process until you put a card into your hand or you exile two cards with the same name, whichever comes first.

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Watery Grave

({T}: Add {U} or {B}.)
As Watery Grave enters, you may pay 2 life. If you don't, it enters tapped.

Force of Negation

If it's not your turn, you may exile a blue card from your hand rather than pay this spell's mana cost.
Counter target noncreature spell. If that spell is countered this way, exile it instead of putting it into its owner's graveyard.

Dress Down

Flash
When Dress Down enters, draw a card.
Creatures lose all abilities.
At the beginning of the end step, sacrifice Dress Down.

Thassa's Oracle

When Thassa's Oracle enters, look at the top X cards of your library, where X is your devotion to blue. Put up to one of them on top of your library and the rest on the bottom of your library in a random order. If X is greater than or equal to the number of cards in your library, you win the game. (Each {U} in the mana costs of permanents you control counts toward your devotion to blue.)

Spell Pierce

Counter target noncreature spell unless its controller pays {2}.

Notion Thief

Flash
If an opponent would draw a card except the first one they draw in each of their draw steps, instead that player skips that draw and you draw a card.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Doomsday

Search your library and graveyard for five cards and exile the rest. Put the chosen cards on top of your library in any order. You lose half your life, rounded up.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Mox Amber

{T}: Add one mana of any color among legendary creatures and planeswalkers you control.

Flusterstorm

Counter target instant or sorcery spell unless its controller pays {1}.
Storm (When you cast this spell, copy it for each spell cast before it this turn. You may choose new targets for the copies.)

Snap

Return target creature to its owner's hand. Untap up to two lands.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.