Winds of Rath

Destroy all creatures that aren't enchanted. They can't be regenerated.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Shifting Shadow

Enchant creature
Enchanted creature has haste and "At the beginning of your upkeep, destroy this creature. Reveal cards from the top of your library until you reveal a creature card. Put that card onto the battlefield and attach Shifting Shadow to it, then put all other cards revealed this way on the bottom of your library in a random order."

Plains

Day of Judgment

Obliterate

This spell can't be countered.
Destroy all artifacts, creatures, and lands. They can't be regenerated.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Ulamog is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Depopulate

Each player who controls a multicolored creature draws a card. Then destroy all creatures.

Mountain

Assemble the Legion

At the beginning of your upkeep, put a muster counter on this enchantment. Then create a 1/1 red and white Soldier creature token with haste for each muster counter on this enchantment.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Chain Reaction

Chain Reaction deals X damage to each creature, where X is the number of creatures on the battlefield.

Augusta, Dean of Order

Other tapped creatures you control get +1/+0.
Other untapped creatures you control get +0/+1.
Whenever you attack, untap each creature you control, then tap any number of creatures you control.

Plargg, Dean of Chaos

{T}, Discard a card: Draw a card.
{4}{R}, {T}: Reveal cards from the top of your library until you reveal a nonlegendary, nonland card with mana value 3 or less. You may cast that card without paying its mana cost. Put all revealed cards not cast this way on the bottom of your library in a random order.

Plargg, Dean of Chaos // Augusta, Dean of Order

Shatter the Sky

Each player who controls a creature with power 4 or greater draws a card. Then destroy all creatures.

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)