Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Sol Ring

Despark

Exile target permanent with mana value 4 or greater.

Sign in Blood

Target player draws two cards and loses 2 life.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Righteous Cause

Whenever a creature attacks, you gain 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Deafening Silence

Each player can't cast more than one noncreature spell each turn.

Terminus

Put all creatures on the bottom of their owners' libraries.
Miracle {W} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

No Mercy

Whenever a creature deals damage to you, destroy it.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Sunscorch Regent

Flying
Whenever an opponent casts a spell, put a +1/+1 counter on Sunscorch Regent and you gain 1 life.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Palace Siege

As Palace Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Speaker of the Heavens

Vigilance, lifelink (Attacking doesn't cause this creature to tap. Damage dealt by this creature also causes you to gain that much life.)
{T}: Create a 4/4 white Angel creature token with flying. Activate only if you have at least 7 life more than your starting life total and only as a sorcery.

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Vindicate

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Athreos, Shroud-Veiled

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
At the beginning of your end step, put a coin counter on another target creature.
Whenever a creature with a coin counter on it dies or is put into exile, return that card to the battlefield under your control.

Soul Warden

Whenever another creature enters, you gain 1 life.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Death Pits of Rath

Whenever a creature is dealt damage, destroy it. It can't be regenerated.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Pristine Talisman

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Obzedat, Ghost Council

When Obzedat, Ghost Council enters, target opponent loses 2 life and you gain 2 life.
At the beginning of your end step, you may exile Obzedat. If you do, return it to the battlefield under its owner's control at the beginning of your next upkeep. It gains haste.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Crushing Disappointment

Each player loses 2 life. You draw two cards.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.