Hopeless Nightmare

When this enchantment enters, each opponent discards a card and loses 2 life.
When this enchantment is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice this enchantment.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Wash Away

Cleave {1}{U}{U} (You may cast this spell for its cleave cost. If you do, remove the words in square brackets.)
Counter target spell [that wasn't cast from its owner's hand].

Necrogoyf

Necrogoyf's power is equal to the number of creature cards in all graveyards.
At the beginning of each player's upkeep, that player discards a card.
Madness {1}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Raven's Crime

Target player discards a card.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Serum Visions

Burglar Rat

When this creature enters, each opponent discards a card.

Negate

Psychic Miasma

Target player discards a card. If a land card is discarded this way, return Psychic Miasma to its owner's hand.

Gnat Miser

Each opponent's maximum hand size is reduced by one.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Funeral Charm

Choose one —
• Target player discards a card.
• Target creature gets +2/-1 until end of turn.
• Target creature gains swampwalk until end of turn. (It can't be blocked as long as defending player controls a Swamp.)

Scroll of Griselbrand

{1}, Sacrifice this artifact: Target opponent discards a card. If you control a Demon, that player loses 3 life.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. This artifact deals 1 damage to you.

Horrifying Revelation

Target player discards a card, then mills a card.

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

Crypt Rats

{X}: This creature deals X damage to each creature and each player. Spend only black mana on X.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Drown in the Loch

Choose one —
• Counter target spell with mana value less than or equal to the number of cards in its controller's graveyard.
• Destroy target creature with mana value less than or equal to the number of cards in its controller's graveyard.

Nephalia Drownyard

{T}: Add {C}.
{1}{U}{B}, {T}: Target player mills three cards.

Necrogen Spellbomb

{B}, Sacrifice this artifact: Target player discards a card.
{1}, Sacrifice this artifact: Draw a card.

Island

Swamp

Dream Salvage

Draw cards equal to the number of cards target opponent discarded this turn.

Locust Miser

Each opponent's maximum hand size is reduced by two.

Mind Shatter

Target player discards X cards at random.

Thought Scour

Target player mills two cards.
Draw a card.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Underworld Dreams

Whenever an opponent draws a card, this enchantment deals 1 damage to that player.

Familiar's Ruse

As an additional cost to cast this spell, return a creature you control to its owner's hand.
Counter target spell.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on this enchantment.
At the beginning of each opponent's upkeep, if that player has no cards in hand and this enchantment has two or more quest counters on it, you may have that player lose 5 life.

Virus Beetle

The Rack

As this artifact enters, choose an opponent.
At the beginning of the chosen player's upkeep, this artifact deals X damage to that player, where X is 3 minus the number of cards in their hand.

Hollowborn Barghest

At the beginning of your upkeep, if you have no cards in hand, each opponent loses 2 life.
At the beginning of each opponent's upkeep, if that player has no cards in hand, they lose 2 life.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Spell Syphon

Counter target spell unless its controller pays {1} for each blue permanent you control.

Blackmail

Target player reveals three cards from their hand and you choose one of them. That player discards that card.

Counterspell

Conjurer's Bauble

{T}, Sacrifice this artifact: Put up to one target card from your graveyard on the bottom of your library. Draw a card.

Wrench Mind

Target player discards two cards unless they discard an artifact card.

Pilfer

Target opponent reveals their hand. You choose a nonland card from it. That player discards that card.

Merfolk Windrobber

Flying
Whenever this creature deals combat damage to a player, that player mills a card. (They put the top card of their library into their graveyard.)
Sacrifice this creature: Draw a card. Activate only if an opponent has eight or more cards in their graveyard.

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Augur of Skulls

{1}{B}: Regenerate this creature.
Sacrifice this creature: Target player discards two cards. Activate only during your upkeep.

Elderfang Disciple

Awaken the Erstwhile

Each player discards all the cards in their hand, then creates that many 2/2 black Zombie creature tokens.

Nezumi Informant

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Liliana's Steward

{T}, Sacrifice this creature: Target opponent discards a card. Activate only as a sorcery.

Feign Death

Until end of turn, target creature gains "When this creature dies, return it to the battlefield tapped under its owner's control with a +1/+1 counter on it."

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Mire's Toll

Target player reveals a number of cards from their hand equal to the number of Swamps you control. You choose one of them. That player discards that card.

Memory Sluice

Target player mills four cards.
Conspire (As you cast this spell, you may tap two untapped creatures you control that share a color with it. When you do, copy it and you may choose a new target for the copy.)

Stream of Thought

Target player mills four cards. You shuffle up to four cards from your graveyard into your library.
Replicate {2}{U}{U} (When you cast this spell, copy it for each time you paid its replicate cost. You may choose new targets for the copies.)

Scry 1. (Look at the top card of your library. You may put that card on the bottom.)
Draw a card.

Dimir Signet

Countersquall

Counter target noncreature spell. Its controller loses 2 life.

Ravenous Rats

When this creature enters, target opponent discards a card.

Rune Snag

Counter target spell unless its controller pays {2} plus an additional {2} for each card named Rune Snag in each graveyard.

Dakra Mystic

{U}, {T}: Each player reveals the top card of their library. You may put the revealed cards into their owners' graveyards. If you don't, each player draws a card.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Megrim

Whenever an opponent discards a card, this enchantment deals 2 damage to that player.

Dream Twist

Target player mills three cards.
Flashback {1}{U} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Piracy Charm

Choose one —
• Target creature gains islandwalk until end of turn. (It can't be blocked as long as defending player controls an Island.)
• Target creature gets +2/-1 until end of turn.
• Target player discards a card.

Cry of Contrition

Target player discards a card.
Haunt (When this spell card is put into a graveyard after resolving, exile it haunting target creature.)
When the creature this card haunts dies, target player discards a card.

Skullcage

At the beginning of each opponent's upkeep, this artifact deals 2 damage to that player unless they have exactly three or exactly four cards in hand.

Perplex

Counter target spell unless its controller discards their hand.
Transmute {1}{U}{B} ({1}{U}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Deprive

As an additional cost to cast this spell, return a land you control to its owner's hand.
Counter target spell.