Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Defiler of Flesh

Menace
As an additional cost to cast black permanent spells, you may pay 2 life. Those spells cost {B} less to cast if you paid life this way. This effect reduces only the amount of black mana you pay.
Whenever you cast a black permanent spell, target creature you control gets +1/+1 and gains menace until end of turn.

Infernal Grasp

Destroy target creature. You lose 2 life.

Shadow of Mortality

If your life total is less than your starting life total, this spell costs {X} less to cast, where X is the difference.

Swamp

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Spawn of Mayhem

Spectacle {1}{B}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Flying, trample
At the beginning of your upkeep, Spawn of Mayhem deals 1 damage to each player. Then if you have 10 or less life, put a +1/+1 counter on Spawn of Mayhem.

Ormendahl, the Corrupter

Flying, trample, lifelink
Sacrifice another creature: Draw a card.

Jerren, Corrupted Bishop

Whenever Jerren, Corrupted Bishop enters or another nontoken Human you control dies, you lose 1 life and create a 1/1 white Human creature token.
{2}: Target Human you control gains lifelink until end of turn.
At the beginning of your end step, if you have exactly 13 life, you may pay {4}{B}{B}. If you do, transform Jerren.

Jerren, Corrupted Bishop // Ormendahl, the Corrupter

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Agadeem, the Undercrypt

As Agadeem, the Undercrypt enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {B}.

Agadeem's Awakening

Return from your graveyard to the battlefield any number of target creature cards that each have a different mana value X or less.

Agadeem's Awakening // Agadeem, the Undercrypt

Ulcerate

Target creature gets -3/-3 until end of turn. You lose 3 life.

Sign in Blood

Target player draws two cards and loses 2 life.

Fatal Push

Destroy target creature if it has mana value 2 or less.
Revolt — Destroy that creature if it has mana value 4 or less instead if a permanent you controlled left the battlefield this turn.