Serum Visions

Baleful Strix

Flying, deathtouch
When Baleful Strix enters, draw a card.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Rona, Sheoldred's Faithful

Whenever you cast an instant or sorcery spell, each opponent loses 1 life.
You may cast Rona, Sheoldred's Faithful from your graveyard by discarding two cards in addition to paying its other costs.

Benevolent Geist

Flying
Noncreature spells you control can't be countered.
If Benevolent Geist would be put into a graveyard from anywhere, exile it instead.

Malevolent Hermit

{U}, Sacrifice Malevolent Hermit: Counter target noncreature spell unless its controller pays {3}.
Disturb {2}{U} (You may cast this card from your graveyard transformed for its disturb cost.)

Malevolent Hermit // Benevolent Geist

Inquisition of Kozilek

Target player reveals their hand. You choose a nonland card from it with mana value 3 or less. That player discards that card.

Ledger Shredder

Flying
Whenever a player casts their second spell each turn, Ledger Shredder connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Winds of Rebuke

Return target nonland permanent to its owner's hand. Each player mills two cards.

Consider

Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
Draw a card.

Gitaxian Probe

({U/P} can be paid with either {U} or 2 life.)
Look at target player's hand.
Draw a card.

Minds Aglow

Join forces — Starting with you, each player may pay any amount of mana. Each player draws X cards, where X is the total amount of mana paid this way.

Ponder

Look at the top three cards of your library, then put them back in any order. You may shuffle.
Draw a card.

Dark Ritual

Solve the Equation

Search your library for an instant or sorcery card, reveal it, put it into your hand, then shuffle.

Mystical Tutor

Search your library for an instant or sorcery card, reveal it, then shuffle and put that card on top.

Preordain

Scry 2, then draw a card. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Talrand, Sky Summoner

Whenever you cast an instant or sorcery spell, create a 2/2 blue Drake creature token with flying.

Portent

Look at the top three cards of target player's library, then put them back in any order. You may have that player shuffle.
Draw a card at the beginning of the next turn's upkeep.

Damnation

Destroy all creatures. They can't be regenerated.

Wavebreak Hippocamp

Whenever you cast your first spell during each opponent's turn, draw a card.

Lier, Disciple of the Drowned

Spells can't be countered.
Each instant and sorcery card in your graveyard has flashback. The flashback cost is equal to that card's mana cost.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Chain of Smog

Target player discards two cards. That player may copy this spell and may choose a new target for that copy.

Murmuring Mystic

Whenever you cast an instant or sorcery spell, create a 1/1 blue Bird Illusion creature token with flying.

Poppet Factory

Creature tokens you control lose all abilities and have base power and toughness 3/3.
At the beginning of your upkeep, you may transform Poppet Factory.

Poppet Stitcher

Whenever you cast an instant or sorcery spell, create a 2/2 black Zombie creature token with decayed. (It can't block. When it attacks, sacrifice it at end of combat.)
At the beginning of your upkeep, if you control three or more creature tokens, you may transform Poppet Stitcher.

Poppet Stitcher // Poppet Factory

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Professor Onyx

Magecraft — Whenever you cast or copy an instant or sorcery spell, each opponent loses 2 life and you gain 2 life.
+1: You lose 1 life. Look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
−3: Each opponent sacrifices a creature with the greatest power among creatures that player controls.
−8: Each opponent may discard a card. If they don't, they lose 3 life. Repeat this process six more times.

Scry 1. (Look at the top card of your library. You may put that card on the bottom.)
Draw a card.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")