Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Kaya the Inexorable

+1: Put a ghostform counter on up to one target nontoken creature. It gains "When this creature dies or is put into exile, return it to its owner's hand and create a 1/1 white Spirit creature token with flying."
−3: Exile target nonland permanent.
−7: You get an emblem with "At the beginning of your upkeep, you may cast a legendary spell from your hand, from your graveyard, or from among cards you own in exile without paying its mana cost."

Rampant Growth

Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Nicol Bolas, God-Pharaoh

+2: Target opponent exiles cards from the top of their library until they exile a nonland card. Until end of turn, you may cast that card without paying its mana cost.
+1: Each opponent exiles two cards from their hand.
−4: Nicol Bolas, God-Pharaoh deals 7 damage to target opponent, creature an opponent controls, or planeswalker an opponent controls.
−12: Exile each nonland permanent your opponents control.

Tasha, the Witch Queen

Whenever you cast a spell you don't own, create a 3/3 black Demon creature token.
+1: Draw a card. For each opponent, exile up to one target instant or sorcery card from that player's graveyard and put a page counter on it.
−3: You may cast a spell from among cards in exile with page counters on them without paying its mana cost.
Tasha, the Witch Queen can be your commander.

Teferi, Time Raveler

Each opponent can cast spells only any time they could cast a sorcery.
+1: Until your next turn, you may cast sorcery spells as though they had flash.
−3: Return up to one target artifact, creature, or enchantment to its owner's hand. Draw a card.

Liliana, Dreadhorde General

Whenever a creature you control dies, draw a card.
+1: Create a 2/2 black Zombie creature token.
−4: Each player sacrifices two creatures.
−9: Each opponent chooses a permanent they control of each permanent type and sacrifices the rest.

Karn's Temporal Sundering

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Target player takes an extra turn after this one. Return up to one target nonland permanent to its owner's hand. Exile Karn's Temporal Sundering.

Urza Assembles the Titans

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Scry 4, then you may reveal the top card of your library. If a planeswalker card is revealed this way, put it into your hand.
II — You may put a planeswalker card with mana value 6 or less from your hand onto the battlefield.
III — You may activate the loyalty abilities of planeswalkers you control twice this turn rather than only once.

Jodah, the Unifier

Legendary creatures you control get +X/+X, where X is the number of legendary creatures you control.
Whenever you cast a legendary spell from your hand, exile cards from the top of your library until you exile a legendary nonland card with lesser mana value. You may cast that card without paying its mana cost. Put the rest on the bottom of your library in a random order.

Yawgmoth's Vile Offering

(You may cast a legendary sorcery only if you control a legendary creature or planeswalker.)
Put up to one target creature or planeswalker card from a graveyard onto the battlefield under your control. Destroy up to one target creature or planeswalker. Exile Yawgmoth's Vile Offering.

Mana Vault

Mana Vault doesn't untap during your untap step.
At the beginning of your upkeep, you may pay {4}. If you do, untap Mana Vault.
At the beginning of your draw step, if Mana Vault is tapped, it deals 1 damage to you.
{T}: Add {C}{C}{C}.

Teferi, Hero of Dominaria

+1: Draw a card. At the beginning of the next end step, untap up to two lands.
−3: Put target nonland permanent into its owner's library third from the top.
−8: You get an emblem with "Whenever you draw a card, exile target permanent an opponent controls."

Nicol Bolas, Dragon-God

Nicol Bolas, Dragon-God has all loyalty abilities of all other planeswalkers on the battlefield.
+1: You draw a card. Each opponent exiles a card from their hand or a permanent they control.
−3: Destroy target creature or planeswalker.
−8: Each opponent who doesn't control a legendary creature or planeswalker loses the game.

Farseek

Search your library for a Plains, Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Chromatic Orrery

You may spend mana as though it were mana of any color.
{T}: Add {C}{C}{C}{C}{C}.
{5}, {T}: Draw a card for each color among permanents you control.

Karn, Scion of Urza

+1: Reveal the top two cards of your library. An opponent chooses one of them. Put that card into your hand and exile the other with a silver counter on it.
−1: Put a card you own with a silver counter on it from exile into your hand.
−2: Create a 0/0 colorless Construct artifact creature token with "This creature gets +1/+1 for each artifact you control."

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Timeless Lotus

Timeless Lotus enters the battlefield tapped.
{T}: Add {W}{U}{B}{R}{G}.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Atraxa, Praetors' Voice

Flying, vigilance, deathtouch, lifelink
At the beginning of your end step, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ugin, the Spirit Dragon

+2: Ugin, the Spirit Dragon deals 3 damage to any target.
−X: Exile each permanent with mana value X or less that's one or more colors.
−10: You gain 7 life, draw seven cards, then put up to seven permanent cards from your hand onto the battlefield.

Jodah, Archmage Eternal

Flying
You may pay {W}{U}{B}{R}{G} rather than pay the mana cost for spells that you cast.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Hour of Promise

Search your library for up to two land cards, put them onto the battlefield tapped, then shuffle. Then if you control three or more Deserts, create two 2/2 black Zombie creature tokens.

Teferi, Who Slows the Sunset

+1: Choose up to one target artifact, up to one target creature, and up to one target land. Untap the chosen permanents you control. Tap the chosen permanents you don't control. You gain 2 life.
−2: Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order.
−7: You get an emblem with "Untap all permanents you control during each opponent's untap step" and "You draw a card during each opponent's draw step."

Vorinclex, Monstrous Raider

Trample, haste
If you would put one or more counters on a permanent or player, put twice that many of each of those kinds of counters on that permanent or player instead.
If an opponent would put one or more counters on a permanent or player, they put half that many of each of those kinds of counters on that permanent or player instead, rounded down.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Mana Crypt

At the beginning of your upkeep, flip a coin. If you lose the flip, Mana Crypt deals 3 damage to you.
{T}: Add {C}{C}.