Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Soul Warden

Whenever another creature enters, you gain 1 life.

Gift of Estates

If an opponent controls more lands than you, search your library for up to three Plains cards, reveal them, put them into your hand, then shuffle.

Return to Dust

Exile target artifact or enchantment. If you cast this spell during your main phase, you may exile up to one other target artifact or enchantment.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Resolute Archangel

Flying
When this creature enters, if your life total is less than your starting life total, it becomes equal to your starting life total.

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Mine Excavation

Return target artifact or enchantment card from a graveyard to its owner's hand.
Conspire (As you cast this spell, you may tap two untapped creatures you control that share a color with it. When you do, copy it and you may choose a new target for the copy.)

Out of Time

When this enchantment enters, untap all creatures, then those creatures phase out until this enchantment leaves the battlefield. Put a time counter on this enchantment for each creature that phased out this way.
Vanishing (At the beginning of your upkeep, remove a time counter from this enchantment. When the last is removed, sacrifice it.)

Skeletal Scrying

As an additional cost to cast this spell, exile X cards from your graveyard.
You draw X cards and you lose X life.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Plains

Fracture

Destroy target artifact, enchantment, or planeswalker.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Angelic Enforcer

Flying
You have hexproof.
This creature's power and toughness are each equal to your life total.
Whenever this creature attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform this creature and your life total becomes 3. Then if this creature didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Thran Dynamo

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice this artifact: Draw a card.

Treasury Thrull

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever this creature attacks, you may return target artifact, creature, or enchantment card from your graveyard to your hand.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: This creature gets +1/+1 until end of turn.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Children of Korlis

Sacrifice this creature: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Disenchant

Mandate of Peace

Cast this spell only during combat.
Your opponents can't cast spells this turn.
End the combat phase. (Remove all attackers and blockers from combat. Exile all spells and abilities from the stack, including this spell.)

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Cataclysmic Gearhulk

Vigilance
When this creature enters, each player chooses an artifact, a creature, an enchantment, and a planeswalker from among the nonland permanents they control, then sacrifices the rest.

Lapse of Certainty

Counter target spell. If that spell is countered this way, put it on top of its owner's library instead of into that player's graveyard.

Netherborn Phalanx

When this creature enters, each opponent loses 1 life for each creature they control.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Burnished Hart

{3}, Sacrifice this creature: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Angel of Grace

Flash
Flying
When this creature enters, until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.
{4}{W}{W}, Exile this card from your graveyard: Your life total becomes 10.

Damnable Pact

Target player draws X cards and loses X life.

Sign in Blood

Target player draws two cards and loses 2 life.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra's power.

Marble Diamond

This artifact enters tapped.
{T}: Add {W}.

Tainted Sigil

{T}, Sacrifice this artifact: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Despark

Exile target permanent with mana value 4 or greater.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Cloudsteel Kirin

Flying
Equipped creature has flying and "You can't lose the game and your opponents can't win the game."
Reconfigure {5} ({5}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Moonlight Bargain

Look at the top five cards of your library. For each card, put that card into your graveyard unless you pay 2 life. Then put the rest into your hand.

Mischievous Poltergeist

Flying
Pay 1 life: Regenerate this creature.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia to its owner's hand.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik.

Exquisite Archangel

Flying
If you would lose the game, instead exile this creature and your life total becomes equal to your starting life total.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Terminus

Put all creatures on the bottom of their owners' libraries.
Miracle {W} (You may cast this card for its miracle cost when you draw it if it's the first card you drew this turn.)

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, this creature gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Pristine Talisman

Knight of the White Orchid

First strike
When this creature enters, if an opponent controls more lands than you, you may search your library for a Plains card, put it onto the battlefield, then shuffle.

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Charcoal Diamond

This artifact enters tapped.
{T}: Add {B}.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Font of Agonies

Whenever you pay life, put that many blood counters on this enchantment.
{1}{B}, Remove four blood counters from this enchantment: Destroy target creature.

Obzedat's Aid

Return target permanent card from your graveyard to the battlefield.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Dark Tutelage

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Razor Barrier

Target permanent you control gains protection from artifacts or from the color of your choice until end of turn.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Aurora of Emrakul

Flying, deathtouch
Whenever this creature attacks, each opponent loses 3 life.

Cryptolith Fragment

This artifact enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform this artifact.

Cryptolith Fragment // Aurora of Emrakul

Faith's Shield

Target permanent you control gains protection from the color of your choice until end of turn.
Fateful hour — If you have 5 or less life, instead you and each permanent you control gain protection from the color of your choice until end of turn.

Sol Ring

Greed

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Transcendence

You don't lose the game for having 0 or less life.
When you have 20 or more life, you lose the game.
Whenever you lose life, you gain 2 life for each 1 life you lost. (Damage dealt to you causes you to lose life.)

Suture Priest

Whenever another creature you control enters, you may gain 1 life.
Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Swamp

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Pact Weapon

As long as this Equipment is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Vindicate

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Tragic Arrogance

For each player, you choose from among the permanents that player controls an artifact, a creature, an enchantment, and a planeswalker. Then each player sacrifices all other nonland permanents they control.