Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis, Unshackled.

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Sol Ring

Forsaken Monument

Colorless creatures you control get +2/+2.
Whenever you tap a permanent for {C}, add an additional {C}.
Whenever you cast a colorless spell, you gain 2 life.

Mire Triton

Deathtouch
When Mire Triton enters, mill two cards and you gain 2 life. (To mill a card, put the top card of your library into your graveyard.)

Moss Diamond

Moss Diamond enters tapped.
{T}: Add {G}.

Feast of Sanity

Whenever you discard a card, Feast of Sanity deals 1 damage to any target and you gain 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Rush of Vitality

Target creature gets +1/+0 and gains lifelink and indestructible until end of turn. (Damage dealt by that creature also causes its controller to gain that much life, and it can't be destroyed by damage or effects that say "destroy.")

Scale the Heights

Put a +1/+1 counter on up to one target creature. You gain 2 life. You may play an additional land this turn.
Draw a card.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Temple of Malady

Temple of Malady enters tapped.
When Temple of Malady enters, scry 1.
{T}: Add {B} or {G}.

Master Chef

Commander creatures you own have "This creature enters with an additional +1/+1 counter on it" and "Other creatures you control enter with an additional +1/+1 counter on them."

Flay Essence

Exile target creature or planeswalker. You gain life equal to the number of counters on it.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Pristine Talisman

Sorin's Thirst

Sorin's Thirst deals 2 damage to target creature and you gain 2 life.

Tamiyo's Safekeeping

Target permanent you control gains hexproof and indestructible until end of turn. You gain 2 life. (A permanent with hexproof and indestructible can't be the target of spells or abilities your opponents control. Damage and effects that say "destroy" don't destroy it.)

Dark Ritual

Erebos's Intervention

Choose one —
• Target creature gets -X/-X until end of turn. You gain X life.
• Exile up to twice X target cards from graveyards.

Lisette, Dean of the Root

Whenever you gain life, you may pay {1}. If you do, put a +1/+1 counter on each creature you control and those creatures gain trample until end of turn.

Valentin, Dean of the Vein

Menace, lifelink
If a nontoken creature an opponent controls would die, exile it instead. When you do, you may pay {2}. If you do, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."

Valentin, Dean of the Vein // Lisette, Dean of the Root

Pulse of Murasa

Return target creature or land card from a graveyard to its owner's hand. You gain 6 life.

Nadier's Nightblade

Whenever a token you control leaves the battlefield, each opponent loses 1 life and you gain 1 life.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Leyline of Abundance

If Leyline of Abundance is in your opening hand, you may begin the game with it on the battlefield.
Whenever you tap a creature for mana, add an additional {G}.
{6}{G}{G}: Put a +1/+1 counter on each creature you control.

Lampad of Death's Vigil

{1}, Sacrifice a creature: Each opponent loses 1 life and you gain 1 life.

Diamond Mare

As Diamond Mare enters, choose a color.
Whenever you cast a spell of the chosen color, you gain 1 life.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Dina, Soul Steeper

Whenever you gain life, each opponent loses 1 life.
{1}, Sacrifice another creature: Dina, Soul Steeper gets +X/+0 until end of turn, where X is the sacrificed creature's power.

Underhanded Designs

Whenever an artifact you control enters, you may pay {1}. If you do, each opponent loses 1 life and you gain 1 life.
{1}{B}, Sacrifice Underhanded Designs: Destroy target creature. Activate only if you control two or more artifacts.

Professor of Zoomancy

When Professor of Zoomancy enters, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."

Hunt for Specimens

Create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."
Learn. (You may reveal a Lesson card you own from outside the game and put it into your hand, or discard a card to draw a card.)

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Fountain of Renewal

At the beginning of your upkeep, you gain 1 life.
{3}, Sacrifice Fountain of Renewal: Draw a card.

Grisly Sigil

Casualty 1 (As you cast this spell, you may sacrifice a creature with power 1 or greater. When you do, copy this spell and you may choose a new target for the copy.)
Choose target creature or planeswalker. If it was dealt noncombat damage this turn, Grisly Sigil deals 3 damage to it and you gain 3 life. Otherwise, Grisly Sigil deals 1 damage to it and you gain 1 life.

Callous Bloodmage

When Callous Bloodmage enters, choose one —
• Create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."
• You draw a card and you lose 1 life.
• Exile target player's graveyard.

Odious Witch

Whenever Odious Witch attacks, defending player loses 1 life and you gain 1 life.

Ragged Recluse

At the beginning of your end step, if you discarded a card this turn, transform Ragged Recluse.

Ragged Recluse // Odious Witch

Arcane Signet

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Night Market Lookout

Whenever Night Market Lookout becomes tapped, each opponent loses 1 life and you gain 1 life.

Tanglebloom

Demon's Horn

Whenever a player casts a black spell, you may gain 1 life.

Tavern Swindler

{T}, Pay 3 life: Flip a coin. If you win the flip, you gain 6 life.

Gift of Paradise

Enchant land
When Gift of Paradise enters, you gain 3 life.
Enchanted land has "{T}: Add two mana of any one color."

Zuran Orb

Gala Greeters

Alliance — Whenever another creature you control enters, choose one that hasn't been chosen this turn —
• Put a +1/+1 counter on Gala Greeters.
• Create a tapped Treasure token.
• You gain 2 life.

Clawing Torment

Enchant artifact or creature
As long as enchanted permanent is a creature, it gets -1/-1 and can't block.
Enchanted permanent has "At the beginning of your upkeep, you lose 1 life."

Orchard Strider

When Orchard Strider enters, create two Food tokens. (They're artifacts with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Basic landcycling {1}{G} ({1}{G}, Discard this card: Search your library for a basic land card, reveal it, put it into your hand, then shuffle.)

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Dawnhart Rejuvenator

When Dawnhart Rejuvenator enters, you gain 3 life.
{T}: Add one mana of any color.

Essence Harvest

Target player loses X life and you gain X life, where X is the greatest power among creatures you control.

Golgari Locket

{T}: Add {B} or {G}.
{B/G}{B/G}{B/G}{B/G}, {T}, Sacrifice Golgari Locket: Draw two cards.