Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Davriel's Shadowfugue

Target player discards two cards and loses 2 life.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Containment Construct

Whenever you discard a card, you may exile that card from your graveyard. If you do, you may play that card this turn.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Liliana, Waker of the Dead

+1: Each player discards a card. Each opponent who can't loses 3 life.
−3: Target creature gets -X/-X until end of turn, where X is the number of cards in your graveyard.
−7: You get an emblem with "At the beginning of combat on your turn, put target creature card from a graveyard onto the battlefield under your control. It gains haste."

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Dreamstealer

Menace
Whenever Dreamstealer deals combat damage to a player, that player discards that many cards.
Eternalize {4}{B}{B} ({4}{B}{B}, Exile this card from your graveyard: Create a token that's a copy of it, except it's a 4/4 black Zombie Human Wizard with no mana cost. Eternalize only as a sorcery.)

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Elvish Doomsayer

When Elvish Doomsayer dies, each opponent discards a card.

Dread Fugue

Cleave {2}{B} (You may cast this spell for its cleave cost. If you do, remove the words in square brackets.)
Target player reveals their hand. You choose a nonland card from it [with mana value 2 or less]. That player discards that card.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Archon of Cruelty

Flying
Whenever Archon of Cruelty enters or attacks, target opponent sacrifices a creature or planeswalker of their choice, discards a card, and loses 3 life. You draw a card and gain 3 life.

No Mercy

Whenever a creature deals damage to you, destroy it.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Ensnaring Bridge

Creatures with power greater than the number of cards in your hand can't attack.

Bad Deal

You draw two cards and each opponent discards two cards. Each player loses 2 life.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Noetic Scales

At the beginning of each player's upkeep, return to its owner's hand each creature that player controls with power greater than the number of cards in their hand.

Junji, the Midnight Sky

Flying, menace
When Junji, the Midnight Sky dies, choose one —
• Each opponent discards two cards and loses 2 life.
• Put target non-Dragon creature card from a graveyard onto the battlefield under your control. You lose 2 life.

Jet Medallion

Black spells you cast cost {1} less to cast.

Liliana Vess

+1: Target player discards a card.
−2: Search your library for a card, then shuffle and put that card on top.
−8: Put all creature cards from all graveyards onto the battlefield under your control.

Sol Ring

Rackling

At the beginning of each opponent's upkeep, Rackling deals X damage to that player, where X is 3 minus the number of cards in their hand.

Witch's Cottage

({T}: Add {B}.)
Witch's Cottage enters tapped unless you control three or more other Swamps.
When Witch's Cottage enters untapped, you may put target creature card from your graveyard on top of your library.

Mind Twist

Target player discards X cards at random.

Cabal Conditioning

Any number of target players each discard a number of cards equal to the highest mana value among permanents you control.

Skullcage

At the beginning of each opponent's upkeep, Skullcage deals 2 damage to that player unless they have exactly three or exactly four cards in hand.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Mind Rot

Divest

Target player reveals their hand. You choose an artifact or creature card from it. That player discards that card.

Swamp

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

The Haunt of Hightower

Flying, lifelink
Whenever The Haunt of Hightower attacks, defending player discards a card.
Whenever a card is put into an opponent's graveyard from anywhere, put a +1/+1 counter on The Haunt of Hightower.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard Takenuma, Abandoned Mire: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Wheel of Torture

At the beginning of each opponent's upkeep, Wheel of Torture deals X damage to that player, where X is 3 minus the number of cards in their hand.

Virus Beetle

When Virus Beetle enters, each opponent discards a card.

Words of Waste

{1}: The next time you would draw a card this turn, each opponent discards a card instead.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Sudden Spoiling

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Until end of turn, creatures target player controls lose all abilities and have base power and toughness 0/2.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice Mind Stone: Draw a card.

Bone Miser

Whenever you discard a creature card, create a 2/2 black Zombie creature token.
Whenever you discard a land card, add {B}{B}.
Whenever you discard a noncreature, nonland card, draw a card.

Funeral Charm

Choose one —
• Target player discards a card.
• Target creature gets +2/-1 until end of turn.
• Target creature gains swampwalk until end of turn. (It can't be blocked as long as defending player controls a Swamp.)

Dying to Serve

Whenever you discard one or more cards, create a tapped 2/2 black Zombie creature token. This ability triggers only once each turn.

Larceny

Whenever a creature you control deals combat damage to a player, that player discards a card.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

The Rack

As The Rack enters, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Oubliette

When Oubliette enters, target creature phases out until Oubliette leaves the battlefield. Tap that creature as it phases in this way. (Auras and Equipment phase out with it. While permanents are phased out, they're treated as though they don't exist.)

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Court of Ambition

When Court of Ambition enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.

Currency Converter

Whenever you discard a card, you may exile that card from your graveyard.
{2}, {T}: Draw a card, then discard a card.
{T}: Put a card exiled with Currency Converter into your graveyard. If it's a land card, create a Treasure token. If it's a nonland card, create a 2/2 black Rogue creature token.

Liliana's Reaver

Deathtouch
Whenever Liliana's Reaver deals combat damage to a player, that player discards a card and you create a tapped 2/2 black Zombie creature token.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Herald of Anguish

Improvise (Your artifacts can help cast this spell. Each artifact you tap after you're done activating mana abilities pays for {1}.)
Flying
At the beginning of your end step, each opponent discards a card.
{1}{B}, Sacrifice an artifact: Target creature gets -2/-2 until end of turn.

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.

Bloodhusk Ritualist

Multikicker {B} (You may pay an additional {B} any number of times as you cast this spell.)
When Bloodhusk Ritualist enters, target opponent discards a card for each time it was kicked.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Burglar Rat

When this creature enters, each opponent discards a card.

Grafdigger's Cage

Creature cards in graveyards and libraries can't enter the battlefield.
Players can't cast spells from graveyards or libraries.

Demogorgon's Clutches

Target opponent discards two cards, mills two cards, and loses 2 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Oppression

Whenever a player casts a spell, that player discards a card.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Rise of the Dark Realms

Put all creature cards from all graveyards onto the battlefield under your control.

Elderfang Disciple

When Elderfang Disciple enters, each opponent discards a card.

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Tasigur's Cruelty

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Each opponent discards two cards.

Mindslicer

When Mindslicer dies, each player discards their hand.

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Thoughtseize

Target player reveals their hand. You choose a nonland card from it. That player discards that card. You lose 2 life.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Anvil of Bogardan

Players have no maximum hand size.
At the beginning of each player's draw step, that player draws an additional card, then discards a card.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Myojin of Night's Reach

Myojin of Night's Reach enters with a divinity counter on it if you cast it from your hand.
Myojin of Night's Reach has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Night's Reach: Each opponent discards their hand.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

Raven's Crime

Target player discards a card.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Awaken the Erstwhile

Each player discards all the cards in their hand, then creates that many 2/2 black Zombie creature tokens.

Hymn to Tourach

Target player discards two cards at random.

Liliana's Specter

Flying
When Liliana's Specter enters, each opponent discards a card.

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Stronghold Rats

Shadow (This creature can block or be blocked by only creatures with shadow.)
Whenever Stronghold Rats deals combat damage to a player, each player discards a card.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Unnerve

Go Blank

Target player discards two cards. Then exile that player's graveyard.

Scythe Specter

Flying
Whenever Scythe Specter deals combat damage to a player, each opponent discards a card. Each player who discarded a card with the highest mana value among cards discarded this way loses life equal to that mana value.

Tourach, Dread Cantor

Kicker {B}{B} (You may pay an additional {B}{B} as you cast this spell.)
Protection from white
Whenever an opponent discards a card, put a +1/+1 counter on Tourach, Dread Cantor.
When Tourach enters, if it was kicked, target opponent discards two cards at random.

Miasmic Mummy

When Miasmic Mummy enters, each player discards a card.

Locust Miser

Each opponent's maximum hand size is reduced by two.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.

Nezumi Shortfang // Stabwhisker the Odious

No Way Out

Target opponent discards two cards. You create a 2/2 black Zombie creature token with decayed. (It can't block. When it attacks, sacrifice it at end of combat.)