Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Alseid of Life's Bounty

Lifelink
{1}, Sacrifice Alseid of Life's Bounty: Target creature or enchantment you control gains protection from the color of your choice until end of turn.

Fountain of Renewal

At the beginning of your upkeep, you gain 1 life.
{3}, Sacrifice Fountain of Renewal: Draw a card.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Orzhov Locket

{T}: Add {W} or {B}.
{W/B}{W/B}{W/B}{W/B}, {T}, Sacrifice Orzhov Locket: Draw two cards.

Scoured Barrens

Scoured Barrens enters tapped.
When Scoured Barrens enters, you gain 1 life.
{T}: Add {W} or {B}.

Sanctify

Destroy target artifact or enchantment. You gain 3 life.

Breena, the Demagogue

Flying
Whenever a player attacks one of your opponents, if that opponent has more life than another of your opponents, that attacking player draws a card and you put two +1/+1 counters on a creature you control.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Vampire Nighthawk

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Ajani's Welcome

Whenever a creature you control enters, you gain 1 life.

Silverquill Campus

Silverquill Campus enters tapped.
{T}: Add {W} or {B}.
{4}, {T}: Scry 1.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Healer's Hawk

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Supernatural Stamina

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Sol Ring

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Soul Warden

Whenever another creature enters, you gain 1 life.

Auriok Champion

Protection from black and from red
Whenever another creature enters, you may gain 1 life.

Greed

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Celestine, the Living Saint

Flying, lifelink
Healing Tears — At the beginning of your end step, return target creature card with mana value X or less from your graveyard to the battlefield, where X is the amount of life you gained this turn.

Nykthos Paragon

Whenever you gain life, you may put that many +1/+1 counters on each creature you control. Do this only once each turn.

Daggerdrome Imp

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Shattered Sanctum

Shattered Sanctum enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Night's Whisper

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Forbidden Orchard

{T}: Add one mana of any color.
Whenever you tap Forbidden Orchard for mana, target opponent creates a 1/1 colorless Spirit creature token.

Despark

Exile target permanent with mana value 4 or greater.

Ashnod's Altar

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Sungrace Pegasus

Flying (This creature can't be blocked except by creatures with flying or reach.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Kabira Crossroads

Kabira Crossroads enters tapped.
When Kabira Crossroads enters, you gain 2 life.
{T}: Add {W}.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Fake Your Own Death

Until end of turn, target creature gets +2/+0 and gains "When this creature dies, return it to the battlefield tapped under its owner's control and you create a Treasure token." (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Seraph of Dawn

Glorious Enforcer

Flying, lifelink
At the beginning of each combat, if you have more life than an opponent, Glorious Enforcer gains double strike until end of turn.

Plains

Healer's Flock

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Witch's Clinic

{T}: Add {C}.
{2}, {T}: Target commander gains lifelink until end of turn.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Sign in Blood

Target player draws two cards and loses 2 life.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Make a Stand

Creatures you control get +1/+0 and gain indestructible until end of turn. (Damage and effects that say "destroy" don't destroy them.)

Swamp

Sky Crier

Flying, lifelink
{3}{W}: You and target opponent each draw a card.

Quietus Spike

Equipped creature has deathtouch.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Animation Module

Whenever one or more +1/+1 counters are put on a permanent you control, you may pay {1}. If you do, create a 1/1 colorless Servo artifact creature token.
{3}, {T}: Choose a counter on target permanent or player. Give that permanent or player another counter of that kind.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Virtus the Veiled

Partner with Gorm the Great (When this creature enters, target player may put Gorm into their hand from their library, then shuffle.)
Deathtouch
Whenever Virtus the Veiled deals combat damage to a player, that player loses half their life, rounded up.

Archangel of Thune

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Whenever you gain life, put a +1/+1 counter on each creature you control.

Sunlit Marsh

({T}: Add {W} or {B}.)
Sunlit Marsh enters tapped.

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Temple of Silence

Temple of Silence enters tapped.
When Temple of Silence enters, scry 1.
{T}: Add {W} or {B}.

Valorous Stance

Choose one —
• Target creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)
• Destroy target creature with toughness 4 or greater.

Aerial Responder

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Radiant Fountain

When Radiant Fountain enters, you gain 2 life.
{T}: Add {C}.

Dark Ritual

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.