Rakdos Signet

Thornbow Archer

Whenever Thornbow Archer attacks, each opponent who doesn't control an Elf loses 1 life.

Blightspeaker

{T}: Target player loses 1 life.
{4}, {T}: Search your library for a Rebel permanent card with mana value 3 or less, put it onto the battlefield, then shuffle.

Mardu Shadowspear

Whenever Mardu Shadowspear attacks, each opponent loses 1 life.
Dash {1}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Dark Ritual

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Florian, Voldaren Scion

First strike
At the beginning of your postcombat main phase, look at the top X cards of your library, where X is the total amount of life your opponents lost this turn. Exile one of those cards and put the rest on the bottom of your library in a random order. You may play the exiled card this turn.

Maggot Carrier

When Maggot Carrier enters the battlefield, each player loses 1 life.

Simian Spirit Guide

Exile Simian Spirit Guide from your hand: Add {R}.

Skirk Prospector

Night Market Lookout

Whenever Night Market Lookout becomes tapped, each opponent loses 1 life and you gain 1 life.

Rite of Flame

Add {R}{R}, then add {R} for each card named Rite of Flame in each graveyard.

Blood Pet

Strike It Rich

Create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Sol Ring

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.