Hideous End

Destroy target nonblack creature. Its controller loses 2 life.

Sinister Possession

Enchant creature
Whenever enchanted creature attacks or blocks, its controller loses 2 life.

Consume Spirit

Spend only black mana on X.
Consume Spirit deals X damage to any target and you gain X life.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Corrosive Mentor

Black creatures you control have wither. (They deal damage to creatures in the form of -1/-1 counters.)

Smolder Initiate

Whenever a player casts a black spell, you may pay {1}. If you do, target player loses 1 life.

Doom Blade

Swamp

Blightcaster

Whenever you cast an enchantment spell, you may have target creature get -2/-2 until end of turn.

Strands of Undeath

Enchant creature
When Strands of Undeath enters, target player discards two cards.
{B}: Regenerate enchanted creature.

Flayed Nim

Whenever Flayed Nim deals combat damage to a creature, that creature's controller loses that much life.
{2}{B}: Regenerate Flayed Nim.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Guul Draz Vampire

As long as an opponent has 10 or less life, Guul Draz Vampire gets +2/+1 and has intimidate. (It can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Shimian Specter

Flying
Whenever Shimian Specter deals combat damage to a player, that player reveals their hand. You choose a nonland card from it. Search that player's graveyard, hand, and library for all cards with the same name as that card and exile them. Then that player shuffles.

Contaminated Ground

Enchant land
Enchanted land is a Swamp.
Whenever enchanted land becomes tapped, its controller loses 2 life.

Thrill-Kill Assassin

Deathtouch
Unleash (You may have this creature enter with a +1/+1 counter on it. It can't block as long as it has a +1/+1 counter on it.)