Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Ancient Craving

You draw three cards and you lose 3 life.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Sylvan Awakening

Until your next turn, all lands you control become 2/2 Elemental creatures with reach, indestructible, and haste. They're still lands.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Stonehoof Chieftain

Trample, indestructible
Whenever another creature you control attacks, it gains trample and indestructible until end of turn.

Fated Retribution

Destroy all creatures and planeswalkers. If it's your turn, scry 2.

Wrath of God

Destroy all creatures. They can't be regenerated.

Stroke of Genius

Harmonize

Ulamog, the Ceaseless Hunger

When you cast this spell, exile two target permanents.
Indestructible
Whenever Ulamog, the Ceaseless Hunger attacks, defending player exiles the top twenty cards of their library.

Kodama's Reach

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Harrow

As an additional cost to cast this spell, sacrifice a land.
Search your library for up to two basic land cards, put them onto the battlefield, then shuffle.

Spearbreaker Behemoth

Indestructible
{1}: Target creature with power 5 or greater gains indestructible until end of turn.

Animist's Awakening

Reveal the top X cards of your library. Put all land cards from among them onto the battlefield tapped and the rest on the bottom of your library in a random order.
Spell mastery — If there are two or more instant and/or sorcery cards in your graveyard, untap those lands.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Worldslayer

Whenever equipped creature deals combat damage to a player, destroy all permanents other than Worldslayer.
Equip {5} ({5}: Attach to target creature you control. Equip only as a sorcery.)

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Explosive Vegetation

Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Nissa, Who Shakes the World

Whenever you tap a Forest for mana, add an additional {G}.
+1: Put three +1/+1 counters on up to one target noncreature land you control. Untap it. It becomes a 0/0 Elemental creature with vigilance and haste that's still a land.
−8: You get an emblem with "Lands you control have indestructible." Search your library for any number of Forest cards, put them onto the battlefield tapped, then shuffle.

Nissa's Renewal

Search your library for up to three basic land cards, put them onto the battlefield tapped, then shuffle. You gain 7 life.

Darksteel Colossus

Trample (This creature can deal excess combat damage to the player or planeswalker it's attacking.)
Indestructible (Damage and effects that say "destroy" don't destroy this creature.)
If Darksteel Colossus would be put into a graveyard from anywhere, reveal Darksteel Colossus and shuffle it into its owner's library instead.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Bust

Boom

Destroy target land you control and target land you don't control.

Boom // Bust

Expedition Map

{2}, {T}, Sacrifice this artifact: Search your library for a land card, reveal it, put it into your hand, then shuffle.

Elspeth, Knight-Errant

+1: Create a 1/1 white Soldier creature token.
+1: Target creature gets +3/+3 and gains flying until end of turn.
−8: You get an emblem with "Artifacts, creatures, enchantments, and lands you control have indestructible."

Painful Truths

Converge — You draw X cards and you lose X life, where X is the number of colors of mana spent to cast this spell.

Blightsteel Colossus

Trample, infect, indestructible
If Blightsteel Colossus would be put into a graveyard from anywhere, reveal Blightsteel Colossus and shuffle it into its owner's library instead.

Pyrohemia

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pyrohemia.
{R}: Pyrohemia deals 1 damage to each creature and each player.

Invoke the Firemind

Choose one —
• Draw X cards.
• Invoke the Firemind deals X damage to any target.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Villainous Wealth

Target opponent exiles the top X cards of their library. You may cast any number of spells with mana value X or less from among them without paying their mana costs.

Jokulhaups

Destroy all artifacts, creatures, and lands. They can't be regenerated.

Soulscour

Desolation Angel

Kicker {W}{W} (You may pay an additional {W}{W} as you cast this spell.)
Flying
When Desolation Angel enters, destroy all lands you control. If it was kicked, destroy all lands instead.

Fracturing Gust

Destroy all artifacts and enchantments. You gain 2 life for each permanent destroyed this way.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Bane of Progress

When Bane of Progress enters, destroy all artifacts and enchantments. Put a +1/+1 counter on Bane of Progress for each permanent destroyed this way.

Rampant Growth

Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Colossus of Akros

Defender, indestructible
{10}: Monstrosity 10. (If this creature isn't monstrous, put ten +1/+1 counters on it and it becomes monstrous.)
As long as Colossus of Akros is monstrous, it has trample and can attack as though it didn't have defender.

Farseek

Search your library for a Plains, Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Pull from Tomorrow

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Boundless Realms

Search your library for up to X basic land cards, where X is the number of lands you control, put them onto the battlefield tapped, then shuffle.

Forest

Plains

Dark Depths

Dark Depths enters with ten ice counters on it.
{3}: Remove an ice counter from Dark Depths.
When Dark Depths has no ice counters on it, sacrifice it. If you do, create Marit Lage, a legendary 20/20 black Avatar creature token with flying and indestructible.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Armageddon

Impervious Greatwurm

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Indestructible

Boompile

{T}: Flip a coin. If you win the flip, destroy all nonland permanents.

Thassa, God of the Sea

Indestructible
As long as your devotion to blue is less than five, Thassa isn't a creature. (Each {U} in the mana costs of permanents you control counts toward your devotion to blue.)
At the beginning of your upkeep, scry 1.
{1}{U}: Target creature you control can't be blocked this turn.

Cultivate

Decree of Annihilation

Exile all artifacts, creatures, and lands from the battlefield, all cards from all graveyards, and all cards from all hands.
Cycling {5}{R}{R} ({5}{R}{R}, Discard this card: Draw a card.)
When you cycle Decree of Annihilation, destroy all lands.

Devastation

Island

Heroic Intervention

Permanents you control gain hexproof and indestructible until end of turn.

Spoils of Victory

Search your library for a Plains, Island, Swamp, Mountain, or Forest card and put that card onto the battlefield. Then shuffle.

Ambition's Cost

Obliterate

This spell can't be countered.
Destroy all artifacts, creatures, and lands. They can't be regenerated.

Swamp

Soul of New Phyrexia

Trample
{5}: Permanents you control gain indestructible until end of turn.
{5}, Exile Soul of New Phyrexia from your graveyard: Permanents you control gain indestructible until end of turn.

Planar Cleansing

Crop Rotation

As an additional cost to cast this spell, sacrifice a land.
Search your library for a land card, put that card onto the battlefield, then shuffle.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Fact or Fiction

Reveal the top five cards of your library. An opponent separates those cards into two piles. Put one pile into your hand and the other into your graveyard.

Kirtar's Wrath

Destroy all creatures. They can't be regenerated.
Threshold — If seven or more cards are in your graveyard, instead destroy all creatures, then create two 1/1 white Spirit creature tokens with flying. Creatures destroyed this way can't be regenerated.

Boros Charm

Choose one —
• Boros Charm deals 4 damage to target player or planeswalker.
• Permanents you control gain indestructible until end of turn.
• Target creature gains double strike until end of turn.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Mountain

Hour of Promise

Search your library for up to two land cards, put them onto the battlefield tapped, then shuffle. Then if you control three or more Deserts, create two 2/2 black Zombie creature tokens.

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Comet Storm

Multikicker {1} (You may pay an additional {1} any number of times as you cast this spell.)
Choose any target, then choose another target for each time this spell was kicked. Comet Storm deals X damage to each of them.

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Magus of the Disk

Magus of the Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Fall of the Thran

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy all lands.
II, III — Each player returns two land cards from their graveyard to the battlefield.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Dig Through Time

Delve (Each card you exile from your graveyard while casting this spell pays for {1}.)
Look at the top seven cards of your library. Put two of them into your hand and the rest on the bottom of your library in any order.

Ulamog, the Infinite Gyre

When you cast this spell, destroy target permanent.
Indestructible
Annihilator 4 (Whenever this creature attacks, defending player sacrifices four permanents of their choice.)
When Ulamog, the Infinite Gyre is put into a graveyard from anywhere, its owner shuffles their graveyard into their library.

Circuitous Route

Search your library for up to two basic land cards and/or Gate cards, put them onto the battlefield tapped, then shuffle.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Verdant Confluence

Choose three. You may choose the same mode more than once.
• Put two +1/+1 counters on target creature.
• Return target permanent card from your graveyard to your hand.
• Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.