The Book of Vile Darkness

At the beginning of your end step, if you lost 2 or more life this turn, create a 2/2 black Zombie creature token.
{T}, Exile The Book of Vile Darkness and artifacts you control named Eye of Vecna and Hand of Vecna: Create Vecna, a legendary 8/8 black Zombie God creature token with indestructible and all triggered abilities of the exiled cards.

Flare of Faith

Target creature gets +2/+2 until end of turn. If it's a Human, instead it gets +3/+3 and gains indestructible until end of turn.

Karfell Kennel-Master

When Karfell Kennel-Master enters, up to two target creatures each get +1/+0 and gain indestructible until end of turn. (Damage and effects that say "destroy" don't destroy them.)

Lorehold Command

Choose two —
• Create a 3/2 red and white Spirit creature token.
• Creatures you control get +1/+0 and gain indestructible and haste until end of turn.
• Lorehold Command deals 3 damage to any target. Target player gains 3 life.
• Sacrifice a permanent, then draw two cards.

Harmonious Emergence

Enchant land you control
Enchanted land is a 4/5 green Spirit creature with vigilance and haste. It's still a land.
If enchanted land would be destroyed, instead sacrifice Harmonious Emergence and that land gains indestructible until end of turn.

Squad Commander

When Squad Commander enters, create a 1/1 white Kor Warrior creature token for each creature in your party. (Your party consists of up to one each of Cleric, Rogue, Warrior, and Wizard.)
At the beginning of combat on your turn, if you have a full party, creatures you control get +1/+0 and gain indestructible until end of turn.

Immersturm Predator

Flying
Whenever this creature becomes tapped, exile up to one target card from a graveyard and put a +1/+1 counter on this creature.
Sacrifice another creature: This creature gains indestructible until end of turn. Tap it.

Voice of the Blessed

Whenever you gain life, put a +1/+1 counter on Voice of the Blessed.
As long as Voice of the Blessed has four or more +1/+1 counters on it, it has flying and vigilance.
As long as Voice of the Blessed has ten or more +1/+1 counters on it, it has indestructible.

Bloodsworn Knight

Bloodsworn Knight's power and toughness are each equal to the number of creature cards in your graveyard.
{1}{B}, Discard a card: Bloodsworn Knight gains indestructible until end of turn. Tap it. (Damage and effects that say "destroy" don't destroy it.)

Bloodsworn Squire

{1}{B}, Discard a card: Bloodsworn Squire gains indestructible until end of turn. Tap it. Then if there are four or more creature cards in your graveyard, transform Bloodsworn Squire. (Damage and effects that say "destroy" don't destroy it.)

Bloodsworn Squire // Bloodsworn Knight

Crew Captain

Haste
Crew Captain has indestructible as long as it entered this turn.

Angelfire Ignition

Put two +1/+1 counters on target creature. It gains vigilance, trample, lifelink, indestructible, and haste until end of turn.
Flashback {2}{R}{W} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Tyrite Sanctum

{T}: Add {C}.
{2}, {T}: Target legendary creature becomes a God in addition to its other types. Put a +1/+1 counter on it.
{4}, {T}, Sacrifice Tyrite Sanctum: Put an indestructible counter on target God.

Icehide Troll

{S}{S}: Icehide Troll gets +2/+0 and gains indestructible until end of turn. Tap it. (Damage and effects that say "destroy" don't destroy it. {S} can be paid with one mana from a snow source.)

Valorous Stance

Choose one —
• Target creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)
• Destroy target creature with toughness 4 or greater.

Skyclave Relic

Kicker {3}
Indestructible
When Skyclave Relic enters, if it was kicked, create two tapped tokens that are copies of Skyclave Relic.
{T}: Add one mana of any color.

Grand Master of Flowers

As long as Grand Master of Flowers has seven or more loyalty counters on him, he's a 7/7 Dragon God creature with flying and indestructible.
+1: Target creature without first strike, double strike, or vigilance can't attack or block until your next turn.
+1: Search your library and/or graveyard for a card named Monk of the Open Hand, reveal it, and put it into your hand. If you search your library this way, shuffle.

Oblivion's Hunger

Target creature you control gains indestructible until end of turn. Draw a card if that creature has a +1/+1 counter on it. (Damage and effects that say "destroy" don't destroy the creature.)

Tamiyo's Safekeeping

Target permanent you control gains hexproof and indestructible until end of turn. You gain 2 life. (A permanent with hexproof and indestructible can't be the target of spells or abilities your opponents control. Damage and effects that say "destroy" don't destroy it.)

Linvala, Shield of Sea Gate

Flying
At the beginning of combat on your turn, if you have a full party, choose target nonland permanent an opponent controls. Until your next turn, it can't attack or block, and its activated abilities can't be activated.
Sacrifice Linvala: Choose hexproof or indestructible. Creatures you control gain that ability until end of turn.

Crackling Emergence

Enchant land you control
Enchanted land is a 3/3 red Spirit creature with haste. It's still a land.
If enchanted land would be destroyed, instead sacrifice Crackling Emergence and that land gains indestructible until end of turn.

Dreadwurm

Landfall — Whenever a land you control enters, Dreadwurm gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Koma, Cosmos Serpent

This spell can't be countered.
At the beginning of each upkeep, create a 3/3 blue Serpent creature token named Koma's Coil.
Sacrifice another Serpent: Choose one —
• Tap target permanent. Its activated abilities can't be activated this turn.
• Koma, Cosmos Serpent gains indestructible until end of turn.

Blizzard Brawl

Choose target creature you control and target creature you don't control. If you control three or more snow permanents, the creature you control gets +1/+0 and gains indestructible until end of turn. Then those creatures fight each other. (Each deals damage equal to its power to the other.)

Arlinn, the Moon's Fury

Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)
+2: Add {R}{G}.
0: Until end of turn, Arlinn, the Moon's Fury becomes a 5/5 Werewolf creature with trample, indestructible, and haste.

Arlinn, the Pack's Hope

Daybound (If a player casts no spells during their own turn, it becomes night next turn.)
+1: Until your next turn, you may cast creature spells as though they had flash, and each creature you control enters with an additional +1/+1 counter on it.
−3: Create two 2/2 green Wolf creature tokens.

Arlinn, the Pack's Hope // Arlinn, the Moon's Fury

Risona, Asari Commander

Haste
Whenever Risona, Asari Commander deals combat damage to a player, if it doesn't have an indestructible counter on it, put an indestructible counter on it.
Whenever combat damage is dealt to you, remove an indestructible counter from Risona.

Akiri, Fearless Voyager

Whenever you attack a player with one or more equipped creatures, draw a card.
{W}: You may unattach an Equipment from a creature you control. If you do, tap that creature and it gains indestructible until end of turn.

Emeria, Shattered Skyclave

As Emeria, Shattered Skyclave enters, you may pay 3 life. If you don't, it enters tapped.
{T}: Add {W}.

Emeria's Call

Create two 4/4 white Angel Warrior creature tokens with flying. Non-Angel creatures you control gain indestructible until your next turn.

Emeria's Call // Emeria, Shattered Skyclave

Selfless Samurai

Whenever a Samurai or Warrior you control attacks alone, it gains lifelink until end of turn.
Sacrifice Selfless Samurai: Another target creature you control gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Deadly Vanity

Choose a creature or planeswalker, then destroy all other creatures and planeswalkers.

Selfless Glyphweaver

Exile Selfless Glyphweaver: Creatures you control gain indestructible until end of turn.

Selfless Glyphweaver // Deadly Vanity

Adamant Will

Target creature gets +2/+2 and gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Professor's Warning

Choose one —
• Put a +1/+1 counter on target creature.
• Target creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Angelheart Protector

When Angelheart Protector enters, target creature you control gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Estwald Shieldbasher

Whenever Estwald Shieldbasher attacks, you may pay {1}. If you do, it gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Kyodai, Soul of Kamigawa

Flash
Flying
When Kyodai, Soul of Kamigawa enters, another target permanent gains indestructible for as long as you control Kyodai.
{W}{U}{B}{R}{G}: Kyodai gets +5/+5 until end of turn.

Ollenbock Escort

Vigilance
Sacrifice Ollenbock Escort: Target creature you control with a +1/+1 counter on it gains lifelink and indestructible until end of turn.

Toski, Bearer of Secrets

This spell can't be countered.
Indestructible
Toski, Bearer of Secrets attacks each combat if able.
Whenever a creature you control deals combat damage to a player, draw a card.