Dina, Soul Steeper

Whenever you gain life, each opponent loses 1 life.
{1}, Sacrifice another creature: Dina, Soul Steeper gets +X/+0 until end of turn, where X is the sacrificed creature's power.

Noxious Gearhulk

Menace
When Noxious Gearhulk enters, you may destroy another target creature. If a creature is destroyed this way, you gain life equal to its toughness.

Nature's Lore

Search your library for a Forest card, put that card onto the battlefield, then shuffle.

Tivash, Gloom Summoner

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay X life, where X is the amount of life you gained this turn. If you do, create an X/X black Demon creature token with flying.

Vault Skirge

({B/P} can be paid with either {B} or 2 life.)
Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Unearth

Return target creature card with mana value 3 or less from your graveyard to the battlefield.
Cycling {2} ({2}, Discard this card: Draw a card.)

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Search for Blex

Look at the top five cards of your library. You may put any number of them into your hand and the rest into your graveyard. You lose 3 life for each card you put into your hand this way.

Blex, Vexing Pest

Other Pests, Bats, Insects, Snakes, and Spiders you control get +1/+1.
When Blex, Vexing Pest dies, you gain 4 life.

Blex, Vexing Pest // Search for Blex

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Gilded Goose

Flying
When Gilded Goose enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
{1}{G}, {T}: Create a Food token.
{T}, Sacrifice a Food: Add one mana of any color.

Willowdusk, Essence Seer

{1}, {T}: Choose another target creature. Put a number of +1/+1 counters on it equal to the amount of life you gained this turn or the amount of life you lost this turn, whichever is greater. Activate only as a sorcery.

Command the Dreadhorde

Choose any number of target creature and/or planeswalker cards in graveyards. Command the Dreadhorde deals damage to you equal to the total mana value of those cards. Put them onto the battlefield under your control.

Beledros Witherbloom

Flying
At the beginning of each upkeep, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."
Pay 10 life: Untap all lands you control. Activate only once each turn.

Once Upon a Time

If this spell is the first spell you've cast this game, you may cast it without paying its mana cost.
Look at the top five cards of your library. You may reveal a creature or land card from among them and put it into your hand. Put the rest on the bottom of your library in a random order.

Rampant Growth

Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Witch's Clinic

{T}: Add {C}.
{2}, {T}: Target commander gains lifelink until end of turn.

Tree of Redemption

Defender
{T}: Exchange your life total with Tree of Redemption's toughness.

Farseek

Search your library for a Plains, Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Lisette, Dean of the Root

Whenever you gain life, you may pay {1}. If you do, put a +1/+1 counter on each creature you control and those creatures gain trample until end of turn.

Valentin, Dean of the Vein

Menace, lifelink
If a nontoken creature an opponent controls would die, exile it instead. When you do, you may pay {2}. If you do, create a 1/1 black and green Pest creature token with "When this creature dies, you gain 1 life."

Valentin, Dean of the Vein // Lisette, Dean of the Root

Basilisk Collar

Equipped creature has deathtouch and lifelink.
Equip {2}

Disciple of Bolas

When Disciple of Bolas enters, sacrifice another creature. You gain X life and draw X cards, where X is that creature's power.

Dreadhorde Invasion

At the beginning of your upkeep, you lose 1 life and amass Zombies 1. (Put a +1/+1 counter on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)
Whenever a Zombie token you control with power 6 or greater attacks, it gains lifelink until end of turn.

Henrika, Infernal Seer

Flying, deathtouch, lifelink
{1}{B}{B}: Each creature you control with flying, deathtouch, and/or lifelink gets +1/+0 until end of turn.

Henrika Domnathi

Flying
At the beginning of combat on your turn, choose one that hasn't been chosen —
• Each player sacrifices a creature.
• You draw a card and you lose 1 life.
• Transform Henrika Domnathi.

Henrika Domnathi // Henrika, Infernal Seer

Withering Boon

As an additional cost to cast this spell, pay 3 life.
Counter target creature spell.

Mortality Spear

This spell costs {2} less to cast if you gained life this turn.
Destroy target nonland permanent.

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Castle Locthwain

Castle Locthwain enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Sol Ring

Patriar's Seal

{T}: Add one mana of any color.
{1}, {T}: Untap target legendary creature you control.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Greed

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Ikra Shidiqi, the Usurper

Menace
Whenever a creature you control deals combat damage to a player, you gain life equal to that creature's toughness.
Partner (You can have two commanders if both have partner.)

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Phyrexian Processor

As Phyrexian Processor enters, pay any amount of life.
{4}, {T}: Create an X/X black Phyrexian Minion creature token, where X is the life paid as Phyrexian Processor entered.

Leyline Prowler

Deathtouch, lifelink
{T}: Add one mana of any color.

Font of Agonies

Whenever you pay life, put that many blood counters on Font of Agonies.
{1}{B}, Remove four blood counters from Font of Agonies: Destroy target creature.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Reckless Spite

Destroy two target nonblack creatures. You lose 5 life.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Infernal Grasp

Destroy target creature. You lose 2 life.

Beast Within

Destroy target permanent. Its controller creates a 3/3 green Beast creature token.

Skyshroud Claim

Search your library for up to two Forest cards, put them onto the battlefield, then shuffle.

Swift End

Destroy target creature or planeswalker. You lose 2 life. (Then exile this card. You may cast the creature later from exile.)

Murderous Rider

Lifelink
When Murderous Rider dies, put it on the bottom of its owner's library.

Murderous Rider // Swift End

Marshland Bloodcaster

Flying
{1}{B}, {T}: Rather than pay the mana cost of the next spell you cast this turn, you may pay life equal to that spell's mana value.

Jarad, Golgari Lich Lord

Jarad, Golgari Lich Lord gets +1/+1 for each creature card in your graveyard.
{1}{B}{G}, Sacrifice another creature: Each opponent loses life equal to the sacrificed creature's power.
Sacrifice a Swamp and a Forest: Return Jarad from your graveyard to your hand.

Sign in Blood

Target player draws two cards and loses 2 life.

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Talisman of Resilience

{T}: Add {C}.
{T}: Add {B} or {G}. Talisman of Resilience deals 1 damage to you.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Reclamation Sage

When Reclamation Sage enters, you may destroy target artifact or enchantment.

Forgotten Ancient

Whenever a player casts a spell, you may put a +1/+1 counter on Forgotten Ancient.
At the beginning of your upkeep, you may move any number of +1/+1 counters from Forgotten Ancient onto other creatures.

Nature's Claim

Destroy target artifact or enchantment. Its controller gains 4 life.

Essence Warden

Whenever another creature enters, you gain 1 life.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Eternity Vessel

Eternity Vessel enters with X charge counters on it, where X is your life total.
Landfall — Whenever a land you control enters, you may have your life total become the number of charge counters on Eternity Vessel.

Dark Ritual

Momentous Fall

As an additional cost to cast this spell, sacrifice a creature.
You draw cards equal to the sacrificed creature's power, then you gain life equal to its toughness.

Harmonize

Golgari Signet

Scavenging Ooze

{G}: Exile target card from a graveyard. If it was a creature card, put a +1/+1 counter on Scavenging Ooze and you gain 1 life.

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Rishkar's Expertise

Draw cards equal to the greatest power among creatures you control.
You may cast a spell with mana value 5 or less from your hand without paying its mana cost.

Timeless Witness

When Timeless Witness enters, return target card from your graveyard to your hand.
Eternalize {5}{G}{G} ({5}{G}{G}, Exile this card from your graveyard: Create a token that's a copy of it, except it's a 4/4 black Zombie Human Shaman with no mana cost. Eternalize only as a sorcery.)