Stinging Lionfish

Whenever you cast your first spell during each opponent's turn, you may tap or untap target nonland permanent.

Staff of the Mind Magus

Whenever you cast a blue spell or an Island you control enters, you gain 1 life.

Trail of Evidence

Whenever you cast an instant or sorcery spell, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Drowned Secrets

Whenever you cast a blue spell, target player mills two cards.

The Mirari Conjecture

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Return target instant card from your graveyard to your hand.
II — Return target sorcery card from your graveyard to your hand.
III — Until end of turn, whenever you cast an instant or sorcery spell, copy it. You may choose new targets for the copy.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Metallurgic Summonings

Whenever you cast an instant or sorcery spell, create an X/X colorless Construct artifact creature token, where X is that spell's mana value.
{3}{U}{U}, Exile Metallurgic Summonings: Return all instant and sorcery cards from your graveyard to your hand. Activate only if you control six or more artifacts.

Gale, Waterdeep Prodigy

Whenever you cast an instant or sorcery spell from your hand, you may cast up to one target card of the other type from your graveyard. If a spell cast from your graveyard this way would be put into your graveyard, exile it instead.
Choose a Background (You can have a Background as a second commander.)

Deekah, Fractal Theorist

Magecraft — Whenever you cast or copy an instant or sorcery spell, create a 0/0 green and blue Fractal creature token. Put X +1/+1 counters on it, where X is that spell's mana value.
{3}{U}: Target creature token can't be blocked this turn.

Shark Typhoon

Whenever you cast a noncreature spell, create an X/X blue Shark creature token with flying, where X is that spell's mana value.
Cycling {X}{1}{U} ({X}{1}{U}, Discard this card: Draw a card.)
When you cycle Shark Typhoon, create an X/X blue Shark creature token with flying.

Serpentine Curve

Create a 0/0 green and blue Fractal creature token. Put X +1/+1 counters on it, where X is one plus the total number of instant and sorcery cards you own in exile and in your graveyard.

Riddleform

Whenever you cast a noncreature spell, you may have Riddleform become a 3/3 Sphinx creature with flying in addition to its other types until end of turn.
{2}{U}: Scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Boseiju, Who Shelters All

Boseiju, Who Shelters All enters tapped.
{T}, Pay 2 life: Add {C}. If that mana is spent on an instant or sorcery spell, that spell can't be countered.

Sentinel Tower

Whenever an instant or sorcery spell is cast during your turn, Sentinel Tower deals damage to any target equal to 1 plus the number of instant and sorcery spells cast before that spell this turn.

Sword Coast Sailor

Commander creatures you own have "Whenever this creature attacks a player, if no opponent has more life than that player, this creature can't be blocked this turn."

Veilstone Amulet

Whenever you cast a spell, creatures you control can't be the targets of spells or abilities your opponents control this turn.

Secrets of the Dead

Whenever you cast a spell from your graveyard, draw a card.

Jace's Sanctum

Instant and sorcery spells you cast cost {1} less to cast.
Whenever you cast an instant or sorcery spell, scry 1.

Spellweaver Volute

Enchant instant card in a graveyard
Whenever you cast a sorcery spell, copy the enchanted instant card. You may cast the copy without paying its mana cost. If you do, exile the enchanted card and attach Spellweaver Volute to another instant card in a graveyard.

Hullbreaker Horror

Flash
This spell can't be countered.
Whenever you cast a spell, choose up to one —
• Return target spell you don't control to its owner's hand.
• Return target nonland permanent to its owner's hand.

Voracious Reader

Prowess (Whenever you cast a noncreature spell, this creature gets +1/+1 until end of turn.)
Instant and sorcery spells you cast cost {1} less to cast.

Curious Homunculus

{T}: Add {C}. Spend this mana only to cast an instant or sorcery spell.
At the beginning of your upkeep, if there are three or more instant and/or sorcery cards in your graveyard, transform Curious Homunculus.

Curious Homunculus // Voracious Reader

Baral, Chief of Compliance

Instant and sorcery spells you cast cost {1} less to cast.
Whenever a spell or ability you control counters a spell, you may draw a card. If you do, discard a card.

Archmage Emeritus

Magecraft — Whenever you cast or copy an instant or sorcery spell, draw a card.

Cloud Key

As Cloud Key enters, choose artifact, creature, enchantment, instant, or sorcery.
Spells you cast of the chosen type cost {1} less to cast.

Sphinx-Bone Wand

Whenever you cast an instant or sorcery spell, you may put a charge counter on Sphinx-Bone Wand. If you do, Sphinx-Bone Wand deals damage equal to the number of charge counters on it to any target.