Ambition's Cost

You draw three cards and you lose 3 life.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Dreadfeast Demon

Flying
At the beginning of your end step, sacrifice a non-Demon creature. If you do, create a token that's a copy of Dreadfeast Demon.

Fell Stinger

Deathtouch
Exploit (When this creature enters, you may sacrifice a creature.)
When Fell Stinger exploits a creature, target player draws two cards and loses 2 life.

Tivash, Gloom Summoner

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay X life, where X is the amount of life you gained this turn. If you do, create an X/X black Demon creature token with flying.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Malakir Cullblade

Whenever a creature an opponent controls dies, put a +1/+1 counter on Malakir Cullblade.

Bloodtracker

Flying
{B}, Pay 2 life: Put a +1/+1 counter on Bloodtracker.
When Bloodtracker leaves the battlefield, draw a card for each +1/+1 counter on it.

Geth, Lord of the Vault

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
{X}{B}: Put target artifact or creature card with mana value X from an opponent's graveyard onto the battlefield under your control tapped. Then that player mills X cards.

Vampire Nighthawk

Flying
Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Ashnod's Altar

Elixir of Immortality

{2}, {T}: You gain 5 life. Shuffle Elixir of Immortality and your graveyard into their owner's library.

Arterial Flow

Each opponent discards two cards. If you control a Vampire, each opponent loses 2 life and you gain 2 life.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Josu Vess, Lich Knight

Kicker {5}{B} (You may pay an additional {5}{B} as you cast this spell.)
Menace
When Josu Vess, Lich Knight enters, if it was kicked, create eight 2/2 black Zombie Knight creature tokens with menace.

Tibalt, Cosmic Impostor

As Tibalt enters, you get an emblem with "You may play cards exiled with Tibalt, Cosmic Impostor, and you may spend mana as though it were mana of any color to cast those spells."
+2: Exile the top card of each player's library.
−3: Exile target artifact or creature.
−8: Exile all graveyards. Add {R}{R}{R}.

Valki, God of Lies

When Valki enters, each opponent reveals their hand. For each opponent, exile a creature card they revealed this way until Valki leaves the battlefield.
{X}: Choose a creature card exiled with Valki with mana value X. Valki becomes a copy of that card.

Valki, God of Lies // Tibalt, Cosmic Impostor

Disciple of Bolas

When Disciple of Bolas enters, sacrifice another creature. You gain X life and draw X cards, where X is that creature's power.

Burden of Greed

Target player loses 1 life for each tapped artifact they control.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Sword-Point Diplomacy

Reveal the top three cards of your library. For each of those cards, put that card into your hand unless any opponent pays 3 life. Then exile the rest.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Timothar, Baron of Bats

Ward—Discard a card.
Whenever another nontoken Vampire you control dies, you may pay {1} and exile it. If you do, create a 1/1 black Bat creature token with flying. It gains "When this creature deals combat damage to a player, sacrifice it and return the exiled card to the battlefield tapped."

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Poison the Cup

Destroy target creature. If this spell was foretold, scry 2.
Foretell {1}{B} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Dark Petition

Search your library for a card, put that card into your hand, then shuffle.
Spell mastery — If there are two or more instant and/or sorcery cards in your graveyard, add {B}{B}{B}.