The Rack

As The Rack enters, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Inquisition of Kozilek

Target player reveals their hand. You choose a nonland card from it with mana value 3 or less. That player discards that card.

Duress

Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.

Mind Twist

Target player discards X cards at random.

Raven's Crime

Target player discards a card.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Nyxathid

As Nyxathid enters, choose an opponent.
Nyxathid gets -1/-1 for each card in the chosen player's hand.

Swamp

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Despise

Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.

Augur of Skulls

{1}{B}: Regenerate Augur of Skulls.
Sacrifice Augur of Skulls: Target player discards two cards. Activate only during your upkeep.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Hypnotic Specter

Flying
Whenever Hypnotic Specter deals damage to an opponent, that player discards a card at random.