Thrull Parasite

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
{T}, Pay 2 life: Remove a counter from target nonland permanent.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Night Market Lookout

Whenever Night Market Lookout becomes tapped, each opponent loses 1 life and you gain 1 life.

Malakir Blood-Priest

When Malakir Blood-Priest enters the battlefield, each opponent loses X life and you gain X life, where X is the number of creatures in your party. (Your party consists of up to one each of Cleric, Rogue, Warrior, and Wizard.)

Vizkopa Confessor

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
When Vizkopa Confessor enters the battlefield, pay any amount of life. Target opponent reveals that many cards from their hand. You choose one of them and exile it.

Insatiable Hemophage

Mutate {2}{B} (If you cast this spell for its mutate cost, put it over or under target non-Human creature you own. They mutate into the creature on top plus all abilities from under it.)
Deathtouch
Whenever this creature mutates, each opponent loses X life and you gain X life, where X is the number of times this creature has mutated.

Tendrils of Agony

Target player loses 2 life and you gain 2 life.
Storm (When you cast this spell, copy it for each spell cast before it this turn. You may choose new targets for the copies.)

Subversion

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Swamp

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Viscera Seer

Sacrifice a creature: Scry 1. (Look at the top card of your library. You may put that card on the bottom of your library.)

Kingpin's Pet

Flying
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Ob Nixilis of the Black Oath

+2: Each opponent loses 1 life. You gain life equal to the life lost this way.
−2: Create a 5/5 black Demon creature token with flying. You lose 2 life.
−8: You get an emblem with "{1}{B}, Sacrifice a creature: You gain X life and draw X cards, where X is the sacrificed creature's power."
Ob Nixilis of the Black Oath can be your commander.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Animate Dead

Enchant creature card in a graveyard
When Animate Dead enters the battlefield, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Animate Dead." Return enchanted creature card to the battlefield under your control and attach Animate Dead to it. When Animate Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

Nocturnal Feeder

Flying
When Nocturnal Feeder dies, each opponent loses 2 life and you gain 2 life.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Tormented Hero

Tormented Hero enters the battlefield tapped.
Heroic — Whenever you cast a spell that targets Tormented Hero, each opponent loses 1 life. You gain life equal to the life lost this way.

Kaya, Ghost Assassin

0: Exile Kaya, Ghost Assassin or up to one target creature. Return that card to the battlefield under its owner's control at the beginning of your next upkeep. You lose 2 life.
−1: Each opponent loses 2 life and you gain 2 life.
−2: Each opponent discards a card and you draw a card.

Vish Kal, Blood Arbiter

Flying, lifelink
Sacrifice a creature: Put X +1/+1 counters on Vish Kal, Blood Arbiter, where X is the sacrificed creature's power.
Remove all +1/+1 counters from Vish Kal: Target creature gets -1/-1 until end of turn for each +1/+1 counter removed this way.

Agent of Masks

Touch of Death

Touch of Death deals 1 damage to target player or planeswalker. You gain 1 life.
Draw a card at the beginning of the next turn's upkeep.

Basilica Guards

Defender
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Falkenrath Noble

Flying
Whenever Falkenrath Noble or another creature dies, target player loses 1 life and you gain 1 life.

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter the battlefield tapped.

Bontu's Monument

Black creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, each opponent loses 1 life and you gain 1 life.

Trespasser's Curse

Enchant player
Whenever a creature enters the battlefield under enchanted player's control, that player loses 1 life and you gain 1 life.

Sorin, Grim Nemesis

+1: Reveal the top card of your library and put that card into your hand. Each opponent loses life equal to its mana value.
−X: Sorin, Grim Nemesis deals X damage to target creature or planeswalker and you gain X life.
−9: Create a number of 1/1 black Vampire Knight creature tokens with lifelink equal to the highest life total among all players.

Scholar of Athreos

{2}{B}: Each opponent loses 1 life. You gain life equal to the life lost this way.

Tenured Inkcaster

When Tenured Inkcaster enters the battlefield, put a +1/+1 counter on target creature.
Whenever a creature you control with a +1/+1 counter on it attacks, each opponent loses 1 life and you gain 1 life.

Spirit of Malevolence

When Spirit of Malevolence dies, each opponent loses 1 life and you gain 1 life.

Syndic of Tithes

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Morsel Theft

Prowl {1}{B} (You may cast this for its prowl cost if you dealt combat damage to a player this turn with a Rogue.)
Target player loses 3 life and you gain 3 life. If this spell's prowl cost was paid, draw a card.

Urborg Syphon-Mage

{2}{B}, {T}, Discard a card: Each other player loses 2 life. You gain life equal to the life lost this way.

Exotic Disease

Domain — Target player loses X life and you gain X life, where X is the number of basic land types among lands you control.

Essence Feed

Target player loses 3 life. You gain 3 life and create three 0/1 colorless Eldrazi Spawn creature tokens. They have "Sacrifice this creature: Add {C}."

Foul-Tongue Shriek

Target opponent loses 1 life for each attacking creature you control. You gain that much life.

Curry Favor

You gain X life and each opponent loses X life, where X is the number of Knights you control.

Smitten Swordmaster

Smitten Swordmaster // Curry Favor

Night's Whisper

Syphon Life

Target player loses 2 life and you gain 2 life.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Ebony Charm

Choose one —
• Target opponent loses 1 life and you gain 1 life.
• Exile up to three target cards from a single graveyard.
• Target creature gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Vampire Sovereign

Flying
When Vampire Sovereign enters the battlefield, target opponent loses 3 life and you gain 3 life.

Certain Death

Destroy target creature. Its controller loses 2 life and you gain 2 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Reaper's Talisman

Whenever equipped creature attacks, it gains deathtouch until end of turn.
Whenever equipped creature attacks alone, defending player loses 2 life and you gain 2 life.
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Bastion of Remembrance

When Bastion of Remembrance enters the battlefield, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Vampire's Kiss

Target player loses 2 life and you gain 2 life. Create two Blood tokens. (They're artifacts with "{1}, {T}, Discard a card, Sacrifice this artifact: Draw a card.")

Treasury Thrull

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever Treasury Thrull attacks, you may return target artifact, creature, or enchantment card from your graveyard to your hand.

Roiling Horror

Roiling Horror's power and toughness are each equal to your life total minus the life total of an opponent with the most life.
Suspend X—{X}{B}{B}{B}. X can't be 0. (Rather than cast this card from your hand, you may pay {X}{B}{B}{B} and exile it with X time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost. It has haste.)
Whenever a time counter is removed from Roiling Horror while it's exiled, target player loses 1 life and you gain 1 life.

Kalastria Healer

Rally — Whenever Kalastria Healer or another Ally enters the battlefield under your control, each opponent loses 1 life and you gain 1 life.

Vampire Neonate

{2}, {T}: Each opponent loses 1 life and you gain 1 life.

Basilica Screecher

High Priest of Penance

Whenever High Priest of Penance is dealt damage, you may destroy target nonland permanent.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Syndicate Enforcer

Vampire Opportunist

{6}{B}: Each opponent loses 2 life and you gain 2 life.

Mind Drain

Target opponent discards two cards, mills a card, and loses 1 life. You gain 1 life. (To mill a card, a player puts the top card of their library into their graveyard.)

Suffer the Past

Exile X target cards from target player's graveyard. For each card exiled this way, that player loses 1 life and you gain 1 life.

Specter of the Fens

Flying
{5}{B}: Target opponent loses 2 life and you gain 2 life.

Needlebite Trap

If an opponent gained life this turn, you may pay {B} rather than pay this spell's mana cost.
Target player loses 5 life and you gain 5 life.

Vampire Spawn

When Vampire Spawn enters the battlefield, each opponent loses 2 life and you gain 2 life.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Ancient Craving

You draw three cards and you lose 3 life.

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Odious Witch

Whenever Odious Witch attacks, defending player loses 1 life and you gain 1 life.

Ragged Recluse

At the beginning of your end step, if you discarded a card this turn, transform Ragged Recluse.

Ragged Recluse // Odious Witch

Gonti's Machinations

Whenever you lose life for the first time each turn, you get {E}. (You get an energy counter. Damage causes loss of life.)
Pay {E}{E}, Sacrifice Gonti's Machinations: Each opponent loses 3 life. You gain life equal to the life lost this way.

Polluted Bonds

Whenever a land enters the battlefield under an opponent's control, that player loses 2 life and you gain 2 life.

Epicure of Blood

Parasitic Impetus

Enchant creature
Enchanted creature gets +2/+2 and is goaded. (It attacks each combat if able and attacks a player other than you if able.)
Whenever enchanted creature attacks, its controller loses 2 life and you gain 2 life.

Cauldron Familiar

When Cauldron Familiar enters the battlefield, each opponent loses 1 life and you gain 1 life.
Sacrifice a Food: Return Cauldron Familiar from your graveyard to the battlefield.

Highway Robber

When Highway Robber enters the battlefield, target opponent loses 2 life and you gain 2 life.

Thief of Hope

Whenever you cast a Spirit or Arcane spell, target opponent loses 1 life and you gain 1 life.
Soulshift 2 (When this creature dies, you may return target Spirit card with mana value 2 or less from your graveyard to your hand.)

Knights of the Black Rose

When Knights of the Black Rose enters the battlefield, you become the monarch.
Whenever an opponent becomes the monarch, if you were the monarch as the turn began, that player loses 2 life and you gain 2 life.

Anointed Procession

If an effect would create one or more tokens under your control, it creates twice that many of those tokens instead.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Ghost Council of Orzhova

When Ghost Council of Orzhova enters the battlefield, target opponent loses 1 life and you gain 1 life.
{1}, Sacrifice a creature: Exile Ghost Council of Orzhova. Return it to the battlefield under its owner's control at the beginning of the next end step.

Grim Haruspex

Morph {B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)
Whenever another nontoken creature you control dies, draw a card.

Obzedat, Ghost Council

When Obzedat, Ghost Council enters the battlefield, target opponent loses 2 life and you gain 2 life.
At the beginning of your end step, you may exile Obzedat. If you do, return it to the battlefield under its owner's control at the beginning of your next upkeep. It gains haste.

Blood Baron of Vizkopa

Lifelink, protection from white and from black
As long as you have 30 or more life and an opponent has 10 or less life, Blood Baron of Vizkopa gets +6/+6 and has flying.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Bontu the Glorified

Menace, indestructible
Bontu the Glorified can't attack or block unless a creature died under your control this turn.
{1}{B}, Sacrifice another creature: Scry 1. Each opponent loses 1 life and you gain 1 life.

Wayward Servant

Whenever another Zombie enters the battlefield under your control, each opponent loses 1 life and you gain 1 life.

Orzhova, the Church of Deals

{T}: Add {C}.
{3}{W}{B}, {T}: Target player loses 1 life and you gain 1 life.

Athreos, God of Passage

Indestructible
As long as your devotion to white and black is less than seven, Athreos isn't a creature.
Whenever another creature you own dies, return it to your hand unless target opponent pays 3 life.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Bloodrite Invoker

{8}: Target player loses 3 life and you gain 3 life.

Underhanded Designs

Whenever an artifact enters the battlefield under your control, you may pay {1}. If you do, each opponent loses 1 life and you gain 1 life.
{1}{B}, Sacrifice Underhanded Designs: Destroy target creature. Activate only if you control two or more artifacts.

Infectious Curse

Enchant player
Spells you cast that target enchanted player cost {1} less to cast.
At the beginning of enchanted player's upkeep, that player loses 1 life and you gain 1 life.

Accursed Witch

Spells your opponents cast that target Accursed Witch cost {1} less to cast.
When Accursed Witch dies, return it to the battlefield transformed under your control attached to target opponent.

Accursed Witch // Infectious Curse

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Sign in Blood

Target player draws two cards and loses 2 life.

Dying Wish

Enchant creature you control
When enchanted creature dies, target player loses X life and you gain X life, where X is its power.

Wall of Limbs

Defender (This creature can't attack.)
Whenever you gain life, put a +1/+1 counter on Wall of Limbs.
{5}{B}{B}, Sacrifice Wall of Limbs: Target player loses X life, where X is Wall of Limbs's power.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Last Caress

Target player loses 1 life and you gain 1 life.
Draw a card.