Leyline of Sanctity

If Leyline of Sanctity is in your opening hand, you may begin the game with it on the battlefield.
You have hexproof. (You can't be the target of spells or abilities your opponents control.)

Leyline of Combustion

If Leyline of Combustion is in your opening hand, you may begin the game with it on the battlefield.
Whenever you and/or at least one permanent you control becomes the target of a spell or ability an opponent controls, Leyline of Combustion deals 2 damage to that player.

Leyline of the Void

If Leyline of the Void is in your opening hand, you may begin the game with it on the battlefield.
If a card would be put into an opponent's graveyard from anywhere, exile it instead.

Lotus Petal

{T}, Sacrifice Lotus Petal: Add one mana of any color.

Opalescence

Each other non-Aura enchantment is a creature in addition to its other types and has base power and base toughness each equal to its mana value.

Leyline of Lightning

If Leyline of Lightning is in your opening hand, you may begin the game with it on the battlefield.
Whenever you cast a spell, you may pay {1}. If you do, Leyline of Lightning deals 1 damage to target player or planeswalker.

Leyline of Lifeforce

If Leyline of Lifeforce is in your opening hand, you may begin the game with it on the battlefield.
Creature spells can't be countered.

Leyline of the Meek

If Leyline of the Meek is in your opening hand, you may begin the game with it on the battlefield.
Creature tokens get +1/+1.

Serra's Sanctum

{T}: Add {W} for each enchantment you control.

Serum Powder

{T}: Add {C}.
Any time you could mulligan and Serum Powder is in your hand, you may exile all the cards from your hand, then draw that many cards. (You can do this in addition to taking mulligans.)

Sphinx of Foresight

You may reveal this card from your opening hand. If you do, scry 3 at the beginning of your first upkeep.
Flying
At the beginning of your upkeep, scry 1.

Leyline of Abundance

If Leyline of Abundance is in your opening hand, you may begin the game with it on the battlefield.
Whenever you tap a creature for mana, add an additional {G}.
{6}{G}{G}: Put a +1/+1 counter on each creature you control.

Leyline of Vitality

If Leyline of Vitality is in your opening hand, you may begin the game with it on the battlefield.
Creatures you control get +0/+1.
Whenever a creature you control enters, you may gain 1 life.

Leyline of Punishment

If Leyline of Punishment is in your opening hand, you may begin the game with it on the battlefield.
Players can't gain life.
Damage can't be prevented.

Once Upon a Time

If this spell is the first spell you've cast this game, you may cast it without paying its mana cost.
Look at the top five cards of your library. You may reveal a creature or land card from among them and put it into your hand. Put the rest on the bottom of your library in a random order.

Leyline of Anticipation

If Leyline of Anticipation is in your opening hand, you may begin the game with it on the battlefield.
You may cast spells as though they had flash.