Damnation

Destroy all creatures. They can't be regenerated.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Grimgrin, Corpse-Born

Grimgrin, Corpse-Born enters tapped and doesn't untap during your untap step.
Sacrifice another creature: Untap Grimgrin and put a +1/+1 counter on it.
Whenever Grimgrin attacks, destroy target creature defending player controls, then put a +1/+1 counter on Grimgrin.

Sludge Monster

Whenever Sludge Monster enters or attacks, put a slime counter on up to one other target creature.
Non-Horror creatures with slime counters on them lose all abilities and have base power and toughness 2/2.

Sol Ring

Phyrexian Crusader

First strike, protection from red and from white
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Baleful Strix

Flying, deathtouch
When Baleful Strix enters, draw a card.

Turn to Frog

Until end of turn, target creature loses all abilities and becomes a blue Frog with base power and toughness 1/1.

Chasm Skulker

Whenever you draw a card, put a +1/+1 counter on Chasm Skulker.
When Chasm Skulker dies, create X 1/1 blue Squid creature tokens with islandwalk, where X is the number of +1/+1 counters on Chasm Skulker. (They can't be blocked as long as defending player controls an Island.)

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Swiftfoot Boots

Equipped creature has hexproof and haste. (It can't be the target of spells or abilities your opponents control. It can attack and {T} no matter when it came under your control.)
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

Corrupted Conscience

Enchant creature
You control enchanted creature.
Enchanted creature has infect. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Viral Drake

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{3}{U}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Shadowspear

Equipped creature gets +1/+1 and has trample and lifelink.
{1}: Permanents your opponents control lose hexproof and indestructible until end of turn.
Equip {2}

Notion Thief

Flash
If an opponent would draw a card except the first one they draw in each of their draw steps, instead that player skips that draw and you draw a card.

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Tetsuko Umezawa, Fugitive

Creatures you control with power or toughness 1 or less can't be blocked.

Contagious Nim

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Counterspell

Cauldron of Souls

{T}: Choose any number of target creatures. Each of those creatures gains persist until end of turn. (When it dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Blightsteel Colossus

Trample, infect, indestructible
If Blightsteel Colossus would be put into a graveyard from anywhere, reveal Blightsteel Colossus and shuffle it into its owner's library instead.

Lazav, the Multifarious

When Lazav, the Multifarious enters, surveil 1. (Look at the top card of your library. You may put it into your graveyard.)
{X}: Lazav, the Multifarious becomes a copy of target creature card in your graveyard with mana value X, except its name is Lazav, the Multifarious, it's legendary in addition to its other types, and it has this ability.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Lazav, Dimir Mastermind

Hexproof
Whenever a creature card is put into an opponent's graveyard from anywhere, you may have Lazav, Dimir Mastermind become a copy of that card, except its name is Lazav, Dimir Mastermind, it's legendary in addition to its other types, and it has hexproof and this ability.

Wrexial, the Risen Deep

Islandwalk, swampwalk (This creature can't be blocked as long as defending player controls an Island or a Swamp.)
Whenever Wrexial, the Risen Deep deals combat damage to a player, you may cast target instant or sorcery card from that player's graveyard without paying its mana cost. If that spell would be put into a graveyard, exile it instead.

Toxrill, the Corrosive

At the beginning of each end step, put a slime counter on each creature you don't control.
Creatures you don't control get -1/-1 for each slime counter on them.
Whenever a creature you don't control with a slime counter on it dies, create a 1/1 black Slug creature token.
{U}{B}, Sacrifice a Slug: Draw a card.

Spark Double

You may have Spark Double enter as a copy of a creature or planeswalker you control, except it enters with an additional +1/+1 counter on it if it's a creature, it enters with an additional loyalty counter on it if it's a planeswalker, and it isn't legendary.

Wizard Class

(Gain the next level as a sorcery to add its ability.)
You have no maximum hand size.
{2}{U}: Level 2
When this Class becomes level 2, draw two cards.
{4}{U}: Level 3
Whenever you draw a card, put a +1/+1 counter on target creature you control.

Deepglow Skate

When Deepglow Skate enters, double the number of each kind of counter on any number of target permanents.

Clone

You may have Clone enter as a copy of any creature on the battlefield.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Sengir, the Dark Baron

Flying
Whenever another creature dies, put two +1/+1 counters on Sengir, the Dark Baron.
Whenever another player loses the game, you gain life equal to that player's life total as the turn began.
Partner (You can have two commanders if both have partner.)

Rapid Hybridization

Destroy target creature. It can't be regenerated. That creature's controller creates a 3/3 green Frog Lizard creature token.

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Fuel for the Cause

Counter target spell, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Phyrexian Vatmother

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, you get a poison counter.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Rhonas's Monument

Green creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, target creature you control gets +2/+2 and gains trample until end of turn.

Vela the Night-Clad

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
Other creatures you control have intimidate.
Whenever Vela the Night-Clad or another creature you control leaves the battlefield, each opponent loses 1 life.

Hand of the Praetors

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Other creatures you control with infect get +1/+1.
Whenever you cast a creature spell with infect, target player gets a poison counter.

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Consecrated Sphinx

Flying
Whenever an opponent draws a card, you may draw two cards.

The Ozolith

Whenever a creature you control leaves the battlefield, if it had counters on it, put those counters on The Ozolith.
At the beginning of combat on your turn, if The Ozolith has counters on it, you may move all counters from The Ozolith onto target creature.

Syr Konrad, the Grim

Whenever another creature dies, or a creature card is put into a graveyard from anywhere other than the battlefield, or a creature card leaves your graveyard, Syr Konrad, the Grim deals 1 damage to each opponent.
{1}{B}: Each player mills a card. (They each put the top card of their library into their graveyard.)

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Sword of Truth and Justice

Equipped creature gets +2/+2 and has protection from white and from blue.
Whenever equipped creature deals combat damage to a player, put a +1/+1 counter on a creature you control, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Equip {2}

Skithiryx, the Blight Dragon

Flying
Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{B}: Skithiryx, the Blight Dragon gains haste until end of turn.
{B}{B}: Regenerate Skithiryx.

Blinkmoth Nexus

{T}: Add {C}.
{1}: Blinkmoth Nexus becomes a 1/1 Blinkmoth artifact creature with flying until end of turn. It's still a land.
{1}, {T}: Target Blinkmoth creature gets +1/+1 until end of turn.

Sakashima's Protege

Flash
Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
You may have Sakashima's Protege enter as a copy of any permanent that entered this turn.

Toothy, Imaginary Friend

Partner with Pir, Imaginative Rascal (When this creature enters, target player may put Pir into their hand from their library, then shuffle.)
Whenever you draw a card, put a +1/+1 counter on Toothy, Imaginary Friend.
When Toothy leaves the battlefield, draw a card for each +1/+1 counter on it.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Contentious Plan

Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Draw a card.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Silumgar, the Drifting Death

Flying, hexproof
Whenever a Dragon you control attacks, creatures defending player controls get -1/-1 until end of turn.

Ring of Xathrid

{2}: Regenerate equipped creature. (The next time that creature would be destroyed this turn, instead tap it, remove it from combat, and heal all damage on it.)
At the beginning of your upkeep, put a +1/+1 counter on equipped creature if it's black.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)