Erebos, Bleak-Hearted

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature.
Whenever another creature you control dies, you may pay 2 life. If you do, draw a card.
{1}{B}, Sacrifice another creature: Target creature gets -2/-1 until end of turn.

Essence Channeler

As long as you've lost life this turn, this creature has flying and vigilance.
Whenever you gain life, put a +1/+1 counter on this creature.
When this creature dies, put its counters on target creature you control.

Dross Harvester

Protection from white
At the beginning of your end step, you lose 4 life.
Whenever a creature dies, you gain 2 life.

Apostle's Blessing

({W/P} can be paid with either {W} or 2 life.)
Target artifact or creature you control gains protection from artifacts or from the color of your choice until end of turn.

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever this creature attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform this creature and your life total becomes 3. Then if this creature didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Bloodbond Vampire

Whenever you gain life, put a +1/+1 counter on this creature.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Exemplar of Light

Flying
Whenever you gain life, put a +1/+1 counter on this creature.
Whenever you put one or more +1/+1 counters on this creature, draw a card. This ability triggers only once each turn.

Aettir and Priwen

Equipped creature has base power and toughness X/X, where X is your life total.
Equip {5}

Cleric of Life's Bond

Whenever another Cleric you control enters, you gain 1 life.
Whenever you gain life for the first time each turn, put a +1/+1 counter on this creature.

Bone Devourer

Flash
Flying
This creature enters with a number of +1/+1 counters on it equal to the number of creatures that died this turn.
When this creature dies, you draw X cards and you lose X life, where X is the number of +1/+1 counters on it.

Excalibur II

Whenever you gain life, put a charge counter on Excalibur II.
Equipped creature gets +1/+1 for each charge counter on Excalibur II.
Equip {3}

Call of the Ring

At the beginning of your upkeep, the Ring tempts you.
Whenever you choose a creature as your Ring-bearer, you may pay 2 life. If you do, draw a card.

Amalia Benavides Aguirre

Ward—Pay 3 life.
Whenever you gain life, Amalia Benavides Aguirre explores. Then destroy all other creatures if its power is exactly 20. (To have this creature explore, reveal the top card of your library. Put that card into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then put the card back or put it into your graveyard.)

Devour in Shadow

Destroy target creature. It can't be regenerated. You lose life equal to that creature's toughness.

Chalice of Death

Chalice of Life

{T}: You gain 1 life. Then if you have at least 10 life more than your starting life total, transform this artifact.

Chalice of Life // Chalice of Death

Blessing of Leeches

Flash
Enchant creature
At the beginning of your upkeep, you lose 1 life.
{0}: Regenerate enchanted creature.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Boon of Erebos

Target creature gets +2/+0 until end of turn. Regenerate it. You lose 2 life.

Carnival of Souls

Whenever a creature enters, you lose 1 life and add {B}.

Dark Knight's Greatsword

Job select (When this Equipment enters, create a 1/1 colorless Hero creature token, then attach this to it.)
Equipped creature gets +3/+0 and is a Knight in addition to its other types.
Chaosbringer — Equip—Pay 3 life. Activate only once each turn.

Divinity of Pride

Flying, lifelink
This creature gets +4/+4 as long as you have 25 or more life.

Bloodtracker

Flying
{B}, Pay 2 life: Put a +1/+1 counter on this creature.
When this creature leaves the battlefield, draw a card for each +1/+1 counter on it.

Barbed Servitor

Indestructible
When this creature enters, suspect it. (It has menace and can't block.)
Whenever this creature deals combat damage to a player, you draw a card and you lose 1 life.
Whenever this creature is dealt damage, target opponent loses that much life.

Aerith Gainsborough

Lifelink
Whenever you gain life, put a +1/+1 counter on Aerith Gainsborough.
When Aerith Gainsborough dies, put X +1/+1 counters on each legendary creature you control, where X is the number of +1/+1 counters on Aerith Gainsborough.

Corpse Augur

When this creature dies, you draw X cards and you lose X life, where X is the number of creature cards in target player's graveyard.

Blood Scrivener

If you would draw a card while you have no cards in hand, instead you draw two cards and you lose 1 life.

Darkstar Augur

Offspring {B} (You may pay an additional {B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Cecil, Redeemed Paladin

Lifelink
Protect — Whenever Cecil attacks, other attacking creatures gain indestructible until end of turn.

Cecil, Dark Knight

Deathtouch
Darkness — Whenever Cecil deals damage, you lose that much life. Then if your life total is less than or equal to half your starting life total, untap Cecil and transform it.

Cecil, Dark Knight // Cecil, Redeemed Paladin

Cruel Bargain

Draw four cards. You lose half your life, rounded up.

Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Arco-Flagellant

Squad {2} (As an additional cost to cast this spell, you may pay {2} any number of times. When this creature enters, create that many tokens that are copies of it.)
This creature can't block.
Endurant — Pay 3 life: This creature gains indestructible until end of turn.

Eye of Vecna

When Eye of Vecna enters, you draw a card and you lose 2 life.
At the beginning of your upkeep, you may pay {2}. If you do, you draw a card and you lose 2 life.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Caustic Bronco

Whenever this creature attacks, reveal the top card of your library and put it into your hand. You lose life equal to that card's mana value if this creature isn't saddled. Otherwise, each opponent loses that much life.
Saddle 3 (Tap any number of other creatures you control with total power 3 or more: This Mount becomes saddled until end of turn. Saddle only as a sorcery.)

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra's power.

Adanto Vanguard

As long as this creature is attacking, it gets +2/+0.
Pay 4 life: This creature gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
This creature gets +2/+2 as long as you have 25 or more life.

Ajani's Pridemate

Crossway Troublemakers

Attacking Vampires you control have deathtouch and lifelink. (Any amount of damage they deal to a creature is enough to destroy it. Damage dealt by those creatures also causes their controller to gain that much life.)
Whenever a Vampire you control dies, you may pay 2 life. If you do, draw a card.

Eumidian Hatchery

{T}, Pay 1 life: Add {B}. Put a hatchling counter on this land.
When this land is put into a graveyard from the battlefield, for each hatchling counter on it, create a 1/1 black Insect creature token with flying.

Diresight

Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Dark Tutelage

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on this creature.

Audacious Thief

Whenever this creature attacks, you draw a card and you lose 1 life.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Celestial Unicorn

Blood Baron of Vizkopa

Lifelink, protection from white and from black
As long as you have 30 or more life and an opponent has 10 or less life, this creature gets +6/+6 and has flying.

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Arrogant Poet

Whenever this creature attacks, you may pay 2 life. If you do, it gains flying until end of turn.

Bond of Agony

As an additional cost to cast this spell, pay X life.
Each other player loses X life.

Death Wish

You may put a card you own from outside the game into your hand. You lose half your life, rounded up. Exile Death Wish.

Dark Favor

Enchant creature
When this Aura enters, you lose 1 life.
Enchanted creature gets +3/+1.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• This creature deals 2 damage to any target and you gain 2 life.

Dreadhorde Invasion

At the beginning of your upkeep, you lose 1 life and amass Zombies 1. (Put a +1/+1 counter on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)
Whenever a Zombie token you control with power 6 or greater attacks, it gains lifelink until end of turn.