Choked Estuary

As Choked Estuary enters, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters tapped.
{T}: Add {U} or {B}.

Tinybones, Trinket Thief

At the beginning of each end step, if an opponent discarded a card this turn, you draw a card and you lose 1 life.
{4}{B}{B}: Each opponent with no cards in hand loses 10 life.

Avatar of Will

If an opponent has no cards in hand, this spell costs {6} less to cast.
Flying

Vicious Rumors

Vicious Rumors deals 1 damage to each opponent. Each opponent discards a card, then mills a card. You gain 1 life.

Lupine Prototype

Lupine Prototype can't attack or block unless a player has no cards in hand.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Gustha's Scepter

{T}: Exile a card from your hand face down. You may look at it for as long as it remains exiled.
{T}: Return a card you own exiled with Gustha's Scepter to your hand.
When you lose control of Gustha's Scepter, put all cards exiled with Gustha's Scepter into their owner's graveyard.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

The Rack

As The Rack enters, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Island

Swamp

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.