Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Cabal Therapist

Menace
At the beginning of your first main phase, you may sacrifice a creature. When you do, choose a nonland card name, then target player reveals their hand and discards all cards with that name.

Drill Bit

Spectacle {B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Target player reveals their hand. You choose a nonland card from it. That player discards that card.

Divest

Target player reveals their hand. You choose an artifact or creature card from it. That player discards that card.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Rackling

At the beginning of each opponent's upkeep, Rackling deals X damage to that player, where X is 3 minus the number of cards in their hand.

The Rack

As The Rack enters, choose an opponent.
At the beginning of the chosen player's upkeep, The Rack deals X damage to that player, where X is 3 minus the number of cards in their hand.

Collective Brutality

Escalate—Discard a card. (Pay this cost for each mode chosen beyond the first.)
Choose one or more —
• Target opponent reveals their hand. You choose an instant or sorcery card from it. That player discards that card.
• Target creature gets -2/-2 until end of turn.
• Target opponent loses 2 life and you gain 2 life.

Augur of Skulls

{1}{B}: Regenerate Augur of Skulls.
Sacrifice Augur of Skulls: Target player discards two cards. Activate only during your upkeep.

Harsh Scrutiny

Target opponent reveals their hand. You choose a creature card from it. That player discards that card. Scry 1.

Hymn to Tourach

Target player discards two cards at random.

Cabal Therapy

Choose a nonland card name. Target player reveals their hand and discards all cards with that name.
Flashback—Sacrifice a creature. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Lay Bare the Heart

Target opponent reveals their hand. You choose a nonlegendary, nonland card from it. That player discards that card.

Distended Mindbender

Emerge {5}{B}{B} (You may cast this spell by sacrificing a creature and paying the emerge cost reduced by that creature's mana value.)
When you cast this spell, target opponent reveals their hand. You choose from it a nonland card with mana value 3 or less and a card with mana value 4 or greater. That player discards those cards.

Megrim

Whenever an opponent discards a card, Megrim deals 2 damage to that player.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Davriel, Rogue Shadowmage

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, Davriel, Rogue Shadowmage deals 2 damage to them.
−1: Target player discards a card.

Distress

Target player reveals their hand. You choose a nonland card from it. That player discards that card.

Lupine Prototype

Lupine Prototype can't attack or block unless a player has no cards in hand.

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Cry of Contrition

Target player discards a card.
Haunt (When this spell card is put into a graveyard after resolving, exile it haunting target creature.)
When the creature Cry of Contrition haunts dies, target player discards a card.

Honden of Night's Reach

At the beginning of your upkeep, target opponent discards a card for each Shrine you control.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Stabwhisker the Odious

At the beginning of each opponent's upkeep, that player loses 1 life for each card fewer than three in their hand.

Nezumi Shortfang

{1}{B}, {T}: Target opponent discards a card. Then if that player has no cards in hand, flip Nezumi Shortfang.

Nezumi Shortfang // Stabwhisker the Odious

Despise

Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.

Fell Specter

Flying
When Fell Specter enters, target opponent discards a card.
Whenever an opponent discards a card, that player loses 2 life.

Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.