Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis, Unshackled.

Grave Pact

Whenever a creature you control dies, each other player sacrifices a creature.

Ophiomancer

At the beginning of each upkeep, if you control no Snakes, create a 1/1 black Snake creature token with deathtouch.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Painful Truths

Converge — You draw X cards and you lose X life, where X is the number of colors of mana spent to cast this spell.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Marchesa's Decree

When Marchesa's Decree enters, you become the monarch.
Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Damnation

Destroy all creatures. They can't be regenerated.

Archfiend of Depravity

Flying
At the beginning of each opponent's end step, that player chooses up to two creatures they control, then sacrifices the rest.

Drana, Liberator of Malakir

Flying, first strike
Whenever Drana, Liberator of Malakir deals combat damage to a player, put a +1/+1 counter on each attacking creature you control.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Entomb

Search your library for a card, put that card into your graveyard, then shuffle.

Drana, the Last Bloodchief

Flying
Whenever Drana, the Last Bloodchief attacks, defending player chooses a nonlegendary creature card in your graveyard. You return that card to the battlefield with an additional +1/+1 counter on it. The creature is a Vampire in addition to its other types.

Exhume

Each player puts a creature card from their graveyard onto the battlefield.

Sower of Discord

Flying
As Sower of Discord enters, choose two players.
Whenever damage is dealt to one of the chosen players, the other chosen player also loses that much life.

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Unspeakable Symbol

Pay 3 life: Put a +1/+1 counter on target creature.

Vindictive Lich

When Vindictive Lich dies, choose one or more. Each mode must target a different player.
• Target opponent sacrifices a creature.
• Target opponent discards two cards.
• Target opponent loses 5 life.

Go for the Throat

Heartless Summoning

Creature spells you cast cost {2} less to cast.
Creatures you control get -1/-1.

Demon's Disciple

When Demon's Disciple enters, each player sacrifices a creature or planeswalker.

Ob Nixilis, the Fallen

Landfall — Whenever a land you control enters, you may have target player lose 3 life. If you do, put three +1/+1 counters on Ob Nixilis, the Fallen.

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Night's Whisper

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Massacre Wurm

When Massacre Wurm enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Stinging Study

You draw X cards and you lose X life, where X is the mana value of a commander you own on the battlefield or in the command zone.

Capital Punishment

Council's dilemma — Starting with you, each player votes for death or taxes. Each opponent sacrifices a creature for each death vote and discards a card for each taxes vote.

The Haunt of Hightower

Flying, lifelink
Whenever The Haunt of Hightower attacks, defending player discards a card.
Whenever a card is put into an opponent's graveyard from anywhere, put a +1/+1 counter on The Haunt of Hightower.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Bitterblossom

At the beginning of your upkeep, you lose 1 life and create a 1/1 black Faerie Rogue creature token with flying.

Oppression

Whenever a player casts a spell, that player discards a card.

Glistening Oil

Enchant creature
Enchanted creature has infect.
At the beginning of your upkeep, put a -1/-1 counter on enchanted creature.
When Glistening Oil is put into a graveyard from the battlefield, return Glistening Oil to its owner's hand.

Liliana's Contract

When Liliana's Contract enters, you draw four cards and you lose 4 life.
At the beginning of your upkeep, if you control four or more Demons with different names, you win the game.

Harvester of Souls

Deathtouch
Whenever another nontoken creature dies, you may draw a card.

Avatar of Woe

If there are ten or more creature cards total in all graveyards, this spell costs {6} less to cast.
Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
{T}: Destroy target creature. It can't be regenerated.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Kothophed, Soul Hoarder

Flying
Whenever a permanent owned by another player is put into a graveyard from the battlefield, you draw a card and you lose 1 life.

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Reaper from the Abyss

Flying
Morbid — At the beginning of each end step, if a creature died this turn, destroy target non-Demon creature.

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters, each player loses a third of their life, rounded up.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature.