Biovisionary

At the beginning of the end step, if you control four or more creatures named Biovisionary, you win the game.

Altered Ego

This spell can't be countered.
You may have this creature enter as a copy of any creature on the battlefield, except it enters with X additional +1/+1 counters on it.

Nissa, Steward of Elements

+2: Scry 2.
0: Look at the top card of your library. If it's a land card or a creature card with mana value less than or equal to the number of loyalty counters on Nissa, you may put that card onto the battlefield.
−6: Untap up to two target lands you control. They become 5/5 Elemental creatures with flying and haste until end of turn. They're still lands.

Body of Research

Create a 0/0 green and blue Fractal creature token. Put X +1/+1 counters on it, where X is the number of cards in your library.

Counterspell

Simic Ascendancy

{1}{G}{U}: Put a +1/+1 counter on target creature you control.
Whenever one or more +1/+1 counters are put on a creature you control, put that many growth counters on this enchantment.
At the beginning of your upkeep, if this enchantment has twenty or more growth counters on it, you win the game.

Roalesk, Apex Hybrid

Flying, trample
When Roalesk enters, put two +1/+1 counters on another target creature you control.
When Roalesk dies, proliferate, then proliferate again. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Koma, World-Eater

This spell can't be countered.
Trample, ward {4}
Whenever Koma deals combat damage to a player, create four 3/3 blue Serpent creature tokens named Koma's Coil.

Zimone, Paradox Sculptor

At the beginning of combat on your turn, put a +1/+1 counter on each of up to two target creatures you control.
{G}{U}, {T}: Double the number of each kind of counter on up to two target creatures and/or artifacts you control.