Sinister Possession

Enchant creature
Whenever enchanted creature attacks or blocks, its controller loses 2 life.

Nezumi Road Captain

Menace
Vehicles you control have menace. (They can't be blocked except by two or more creatures.)

Okiba Reckoner Raid

(As this Saga enters and after your draw step, add a lore counter.)
I, II — Each opponent loses 1 life and you gain 1 life.
III — Exile this Saga, then return it to the battlefield transformed under your control.

Okiba Reckoner Raid // Nezumi Road Captain

Widow's Walk

Whenever a creature you control attacks alone, it gets +1/+0 and gains deathtouch until end of turn.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Derelict Attic

When you unlock this door, you draw two cards and you lose 2 life.
(You may cast either half. That door unlocks on the battlefield. As a sorcery, you may pay the mana cost of a locked door to unlock it.)

Derelict Attic // Widow's Walk

Hopeless Nightmare

When this enchantment enters, each opponent discards a card and loses 2 life.
When this enchantment is put into a graveyard from the battlefield, scry 2.
{2}{B}: Sacrifice this enchantment.

Contaminated Bond

Enchant creature (Target a creature as you cast this. This card enters attached to that creature.)
Whenever enchanted creature attacks or blocks, its controller loses 3 life.

Grim Guardian

Constellation — Whenever this creature or another enchantment you control enters, each opponent loses 1 life.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Clawing Torment

Enchant artifact or creature
As long as enchanted permanent is a creature, it gets -1/-1 and can't block.
Enchanted permanent has "At the beginning of your upkeep, you lose 1 life."

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Swamp

Wicked Visitor

Whenever an enchantment you control is put into a graveyard from the battlefield, each opponent loses 1 life.

Balemurk Leech

Eerie — Whenever an enchantment you control enters and whenever you fully unlock a Room, each opponent loses 1 life.