Pact Weapon

As long as this Equipment is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Despark

Exile target permanent with mana value 4 or greater.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Zombify

Return target creature card from your graveyard to the battlefield.

Charming Prince

When this creature enters, choose one —
• Scry 2.
• You gain 3 life.
• Exile another target creature you own. Return it to the battlefield under your control at the beginning of the next end step.

Revoke Privileges

Enchant creature
Enchanted creature can't attack, block, or crew Vehicles.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Prison Break

Return target creature card from your graveyard to the battlefield with an additional +1/+1 counter on it.
Mayhem {3}{B} (You may cast this card from your graveyard for {3}{B} if you discarded it this turn. Timing rules still apply.)

Plains

Teleportation Circle

At the beginning of your end step, exile up to one target artifact or creature you control, then return that card to the battlefield under its owner's control.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Vile Entomber

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
When this creature enters, search your library for a card, put that card into your graveyard, then shuffle.

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Spectral Grasp

Enchant creature
Enchanted creature can't attack you or planeswalkers you control.
Enchanted creature can't block creatures you control.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Flicker of Fate

Exile target creature or enchantment, then return it to the battlefield under its owner's control.

Viper's Kiss

Enchant creature
Enchanted creature gets -1/-1, and its activated abilities can't be activated.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. This artifact deals 1 damage to you.

Jet Medallion

Black spells you cast cost {1} less to cast.

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Sol Ring

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Mister Negative

Vigilance, lifelink
Darkforce Inversion — When Mister Negative enters, you may exchange life totals with target opponent. If you lost life this way, draw that many cards.

Conjurer's Closet

At the beginning of your end step, you may exile target creature you control, then return that card to the battlefield under your control.

Oppressive Rays

Enchant creature
Enchanted creature can't attack or block unless its controller pays {3}.
Activated abilities of enchanted creature cost {3} more to activate.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Temple of Silence

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {W} or {B}.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Gwenom, Remorseless

Deathtouch, lifelink
Whenever Gwenom attacks, until end of turn, you may look at the top card of your library any time and you may play cards from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.

Arcane Signet

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Auramancer

When this creature enters, you may return target enchantment card from your graveyard to your hand.

Seam Rip

When this enchantment enters, exile target nonland permanent an opponent controls with mana value 2 or less until this enchantment leaves the battlefield.

Parker Luck

At the beginning of your end step, two target players each reveal the top card of their library. They each lose life equal to the mana value of the card revealed by the other player. Then they each put the card they revealed into their hand.

Liminal Hold

When this enchantment enters, exile up to one target nonland permanent an opponent controls until this enchantment leaves the battlefield. You gain 2 life.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Thought Vessel

Blood Pact

Target player draws two cards and loses 2 life.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: This creature gets +1/+1 until end of turn.

Pitiless Horde

At the beginning of your upkeep, you lose 2 life.
Dash {2}{B}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Fortuitous Find

Choose one or both —
• Return target artifact card from your graveyard to your hand.
• Return target creature card from your graveyard to your hand.

Swamp

Final Parting

Search your library for two cards. Put one into your hand and the other into your graveyard. Then shuffle.

Stasis Snare

Flash (You may cast this spell any time you could cast an instant.)
When this enchantment enters, exile target creature an opponent controls until this enchantment leaves the battlefield.

Midnight Snack

Raid — At the beginning of your end step, if you attacked this turn, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")
{2}{B}, Sacrifice this enchantment: Target opponent loses X life, where X is the amount of life you gained this turn.

Open the Armory

Search your library for an Aura or Equipment card, reveal it, put it into your hand, then shuffle.

Awe Strike

The next time target creature would deal damage this turn, prevent that damage. You gain life equal to the damage prevented this way.

Sphere of Safety

Creatures can't attack you or planeswalkers you control unless their controller pays {X} for each of those creatures, where X is the number of enchantments you control.

Ill-Gotten Inheritance

At the beginning of your upkeep, this enchantment deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice this enchantment: It deals 4 damage to target opponent and you gain 4 life.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Wayfarer's Bauble

{2}, {T}, Sacrifice this artifact: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Sign in Blood

Wishclaw Talisman

This artifact enters with three wish counters on it.
{1}, {T}, Remove a wish counter from this artifact: Search your library for a card, put it into your hand, then shuffle. An opponent gains control of this artifact. Activate only during your turn.

Disenchant

Bitter Revelation

Look at the top four cards of your library. Put two of them into your hand and the rest into your graveyard. You lose 2 life.

Orzhov Signet

Tombstone, Career Criminal

When Tombstone enters, return target Villain card from your graveyard to your hand.
Villain spells you cast cost {1} less to cast.

Mortify

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Risky Research

Surveil 2, then draw two cards. You lose 2 life. (To surveil 2, look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)