Hapatra, Vizier of Poisons

Whenever Hapatra, Vizier of Poisons deals combat damage to a player, you may put a -1/-1 counter on target creature.
Whenever you put one or more -1/-1 counters on a creature, create a 1/1 green Snake creature token with deathtouch.

Fathom Mage

Evolve (Whenever a creature you control enters, if that creature has greater power or toughness than this creature, put a +1/+1 counter on this creature.)
Whenever a +1/+1 counter is put on Fathom Mage, you may draw a card.

Simic Ascendancy

{1}{G}{U}: Put a +1/+1 counter on target creature you control.
Whenever one or more +1/+1 counters are put on a creature you control, put that many growth counters on Simic Ascendancy.
At the beginning of your upkeep, if Simic Ascendancy has twenty or more growth counters on it, you win the game.

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Obelisk Spider

Reach
Whenever Obelisk Spider deals combat damage to a creature, put a -1/-1 counter on that creature.
Whenever you put one or more -1/-1 counters on a creature, each opponent loses 1 life and you gain 1 life.

Song of Freyalise

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Until your next turn, creatures you control gain "{T}: Add one mana of any color."
III — Put a +1/+1 counter on each creature you control. Those creatures gain vigilance, trample, and indestructible until end of turn.

Incremental Blight

Put a -1/-1 counter on target creature, two -1/-1 counters on another target creature, and three -1/-1 counters on a third target creature.

Skinrender

When Skinrender enters, put three -1/-1 counters on target creature.

Flourishing Defenses

Whenever a -1/-1 counter is put on a creature, you may create a 1/1 green Elf Warrior creature token.

Decimator Beetle

When Decimator Beetle enters, put a -1/-1 counter on target creature you control.
Whenever Decimator Beetle attacks, remove a -1/-1 counter from target creature you control and put a -1/-1 counter on up to one target creature defending player controls.

Sol Ring

Harbinger of Night

At the beginning of your upkeep, put a -1/-1 counter on each creature.

Karn's Bastion

{T}: Add {C}.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Rishkar, Peema Renegade

When Rishkar, Peema Renegade enters, put a +1/+1 counter on each of up to two target creatures.
Each creature you control with a counter on it has "{T}: Add {G}."

Nest of Scarabs

Whenever you put one or more -1/-1 counters on a creature, create that many 1/1 black Insect creature tokens.

Pir, Imaginative Rascal

Partner with Toothy, Imaginary Friend (When this creature enters, target player may put Toothy into their hand from their library, then shuffle.)
If one or more counters would be put on a permanent your team controls, that many plus one of each of those kinds of counters are put on that permanent instead.

Pollenbright Druid

When Pollenbright Druid enters, choose one —
• Put a +1/+1 counter on target creature.
• Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Abrupt Decay

This spell can't be countered.
Destroy target nonland permanent with mana value 3 or less.

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Sakura-Tribe Elder

Sacrifice Sakura-Tribe Elder: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Contagion Engine

When Contagion Engine enters, put a -1/-1 counter on each creature target player controls.
{4}, {T}: Proliferate twice. (Choose any number of permanents and/or players, then give each another counter of each kind already there. Then do it again.)

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Eternal Witness

When Eternal Witness enters, you may return target card from your graveyard to your hand.

Counterspell

Predator Ooze

Indestructible
Whenever Predator Ooze attacks, put a +1/+1 counter on it.
Whenever a creature dealt damage by Predator Ooze this turn dies, put a +1/+1 counter on Predator Ooze.

Crumbling Ashes

At the beginning of your upkeep, destroy target creature with a -1/-1 counter on it.

Shirei, Shizo's Caretaker

Whenever a creature with power 1 or less is put into your graveyard from the battlefield, you may return that card to the battlefield at the beginning of the next end step if Shirei, Shizo's Caretaker is still on the battlefield.

Plaxcaster Frogling

Graft 3 (This creature enters with three +1/+1 counters on it. Whenever another creature enters, you may move a +1/+1 counter from this creature onto it.)
{2}: Target creature with a +1/+1 counter on it gains shroud until end of turn. (It can't be the target of spells or abilities.)

Nissa, Voice of Zendikar

+1: Create a 0/1 green Plant creature token.
−2: Put a +1/+1 counter on each creature you control.
−7: You gain X life and draw X cards, where X is the number of lands you control.

Winged Temple of Orazca

(Transforms from Hadana's Climb.)
{T}: Add one mana of any color.
{1}{G}{U}, {T}: Target creature you control gains flying and gets +X/+X until end of turn, where X is its power.

Hadana's Climb

At the beginning of combat on your turn, put a +1/+1 counter on target creature you control. Then if that creature has three or more +1/+1 counters on it, transform Hadana's Climb.

Hadana's Climb // Winged Temple of Orazca

Sidisi, Undead Vizier

Deathtouch
Exploit (When this creature enters, you may sacrifice a creature.)
When Sidisi, Undead Vizier exploits a creature, you may search your library for a card, put it into your hand, then shuffle.

Cultivate

Search your library for up to two basic land cards, reveal those cards, put one onto the battlefield tapped and the other into your hand, then shuffle.

Novijen, Heart of Progress

{T}: Add {C}.
{G}{U}, {T}: Put a +1/+1 counter on each creature that entered this turn.

Volrath, the Shapestealer

At the beginning of combat on your turn, put a -1/-1 counter on up to one target creature.
{1}: Until your next turn, Volrath, the Shapestealer becomes a copy of target creature with a counter on it, except it's 7/5 and it has this ability.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Farseek

Search your library for a Plains, Island, Swamp, or Mountain card, put it onto the battlefield tapped, then shuffle.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Vraska the Unseen

+1: Until your next turn, whenever a creature deals combat damage to Vraska the Unseen, destroy that creature.
−3: Destroy target nonland permanent.
−7: Create three 1/1 black Assassin creature tokens with "Whenever this creature deals combat damage to a player, that player loses the game."

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Burgeoning

Whenever an opponent plays a land, you may put a land card from your hand onto the battlefield.

Dictate of Erebos

Flash
Whenever a creature you control dies, each opponent sacrifices a creature of their choice.

Necroskitter

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls with a -1/-1 counter on it dies, you may return that card to the battlefield under your control.

Kodama's Reach

Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Assassin's Trophy

Destroy target permanent an opponent controls. Its controller may search their library for a basic land card, put it onto the battlefield, then shuffle.

Evolution Sage

Landfall — Whenever a land you control enters, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Generous Patron

When Generous Patron enters, support 2. (Put a +1/+1 counter on each of up to two other target creatures.)
Whenever you put one or more counters on a creature you don't control, draw a card.

Deathreap Ritual

Morbid — At the beginning of each end step, if a creature died this turn, you may draw a card.