Grievous Wound

Enchant player
Enchanted player can't gain life.
Whenever enchanted player is dealt damage, they lose half their life, rounded up.

Doomsday Excruciator

Flying
When this creature enters, if it was cast, each player exiles all but the bottom six cards of their library face down.
At the beginning of your upkeep, draw a card.

Swamp

Decree of Annihilation

Exile all artifacts, creatures, and lands from the battlefield, all cards from all graveyards, and all cards from all hands.
Cycling {5}{R}{R} ({5}{R}{R}, Discard this card: Draw a card.)
When you cycle this card, destroy all lands.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Bearer of the Heavens

When this creature dies, destroy all permanents at the beginning of the next end step.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Requiem Monolith

{T}: Until end of turn, target creature gains "Whenever this creature is dealt damage, you draw that many cards and lose that much life." That creature's controller may have this artifact deal 1 damage to it. Activate only as a sorcery.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Ruination

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Nefarious Lich

If damage would be dealt to you, exile that many cards from your graveyard instead. If you can't, you lose the game.
If you would gain life, draw that many cards instead.
When this enchantment leaves the battlefield, you lose the game.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Lich's Mastery

Hexproof
You can't lose the game.
Whenever you gain life, draw that many cards.
Whenever you lose life, for each 1 life you lost, exile a permanent you control or a card from your hand or graveyard.
When Lich's Mastery leaves the battlefield, you lose the game.

Mountain

Blood Tribute

Kicker—Tap an untapped Vampire you control. (You may tap a Vampire you control in addition to any other costs as you cast this spell.)
Target opponent loses half their life, rounded up. If this spell was kicked, you gain life equal to the life lost this way.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Ugin's Nexus

If a player would begin an extra turn, that player skips that turn instead.
If Ugin's Nexus would be put into a graveyard from the battlefield, instead exile it and take an extra turn after this one.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Panoptic Mirror

Imprint — {X}, {T}: You may exile an instant or sorcery card with mana value X from your hand.
At the beginning of your upkeep, you may copy a card exiled with this artifact. If you do, you may cast the copy without paying its mana cost.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Orcish Bowmasters

Flash
When this creature enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, this creature deals 1 damage to any target. Then amass Orcs 1.

Searstep Pathway

Blightstep Pathway

Blightstep Pathway // Searstep Pathway

Evereth, Viceroy of Plunder

Flying
Sacrifice another creature or artifact: Put a +1/+1 counter on Evereth. If the sacrificed permanent was a Treasure, Evereth gains lifelink until end of turn. Activate only as a sorcery.
When Evereth dies, you may pay {1}{B/R}. When you do, Evereth deals damage equal to its power to each opponent.

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.

The Lord of Pain

Menace
Your opponents can't gain life.
Whenever a player casts their first spell each turn, choose another target player. The Lord of Pain deals damage equal to that spell's mana value to the chosen player.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Rakdos, Lord of Riots

You can't cast Rakdos unless an opponent lost life this turn.
Flying, trample
Creature spells you cast cost {1} less to cast for each 1 life your opponents have lost this turn.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Ancestral Statue

When this creature enters, return a nonland permanent you control to its owner's hand.

Bontu the Glorified

Menace, indestructible
Bontu can't attack or block unless a creature died under your control this turn.
{1}{B}, Sacrifice another creature: Scry 1. Each opponent loses 1 life and you gain 1 life.

Lich

As this enchantment enters, you lose life equal to your life total.
You don't lose the game for having 0 or less life.
If you would gain life, draw that many cards instead.
Whenever you're dealt damage, sacrifice that many nontoken permanents. If you can't, you lose the game.
When this enchantment is put into a graveyard from the battlefield, you lose the game.

Imperial Seal

Rakdos, the Muscle

Flying, trample
Whenever you sacrifice another creature, exile cards equal to its mana value from the top of target player's library. Until your next end step, you may play those cards, and mana of any type can be spent to cast those spells.
Sacrifice another creature: Rakdos gains indestructible until end of turn. Tap it. Activate only once each turn.

Trazyn the Infinite

Deathtouch
Prismatic Gallery — As long as Trazyn is on the battlefield, it has all activated abilities of all artifact cards in your graveyard.

Ebondeath, Dracolich

Flash
Flying
Ebondeath enters tapped.
You may cast this card from your graveyard if a creature not named Ebondeath, Dracolich died this turn.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Temporal Extortion

When you cast this spell, any player may pay half their life, rounded up. If a player does, counter Temporal Extortion.
Take an extra turn after this one.

Shared Trauma

Join forces — Starting with you, each player may pay any amount of mana. Each player mills X cards, where X is the total amount of mana paid this way.

Underworld Dreams

Whenever an opponent draws a card, this enchantment deals 1 damage to that player.

Razorkin Needlehead

This creature has first strike during your turn.
Whenever an opponent draws a card, this creature deals 1 damage to them.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

Epicure of Blood

Gwenom, Remorseless

Deathtouch, lifelink
Whenever Gwenom attacks, until end of turn, you may look at the top card of your library any time and you may play cards from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Rakdos, Patron of Chaos

Flying, trample
At the beginning of your end step, target opponent may sacrifice two nonland, nontoken permanents of their choice. If they don't, you draw two cards.

Ifrit, Warden of Inferno

(As this Saga enters and after your draw step, add a lore counter.)
I — Lunge — Ifrit fights up to one other target creature.
II, III — Brimstone — Add {R}{R}{R}{R}. If Ifrit has three or more lore counters on it, exile it, then return it to the battlefield (front face up).

Clive, Ifrit's Dominant

When Clive enters, you may discard your hand, then draw cards equal to your devotion to red. (Each {R} in the mana costs of permanents you control counts toward your devotion to red.)
{4}{R}{R}, {T}: Exile Clive, then return it to the battlefield transformed under its owner's control. Activate only as a sorcery.

Clive, Ifrit's Dominant // Ifrit, Warden of Inferno

Bloodthirsty Conqueror

Flying, deathtouch
Whenever an opponent loses life, you gain that much life. (Damage causes loss of life.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Sephiroth, One-Winged Angel

Flying
Super Nova — As this creature transforms into Sephiroth, One-Winged Angel, you get an emblem with "Whenever a creature dies, target opponent loses 1 life and you gain 1 life."
Whenever Sephiroth attacks, you may sacrifice any number of other creatures. If you do, draw that many cards.

Sephiroth, Fabled SOLDIER

Whenever Sephiroth enters or attacks, you may sacrifice another creature. If you do, draw a card.
Whenever another creature dies, target opponent loses 1 life and you gain 1 life. If this is the fourth time this ability has resolved this turn, transform Sephiroth.

Sephiroth, Fabled SOLDIER // Sephiroth, One-Winged Angel

Shard of the Nightbringer

Flying
Drain Life — When this creature enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Destructive Force

Each player sacrifices five lands of their choice. Destructive Force deals 5 damage to each creature.

Roiling Vortex

At the beginning of each player's upkeep, this enchantment deals 1 damage to them.
Whenever a player casts a spell, if no mana was spent to cast that spell, this enchantment deals 5 damage to that player.
{R}: Your opponents can't gain life this turn.

Drakuseth, Maw of Flames

Flying
Whenever Drakuseth attacks, it deals 4 damage to any target and 3 damage to each of up to two other targets.

Razaketh, the Foulblooded

Flying, trample
Pay 2 life, Sacrifice another creature: Search your library for a card, put that card into your hand, then shuffle.

Sanguine Syphoner

Whenever this creature attacks, each opponent loses 1 life and you gain 1 life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: This artifact deals 50 damage to any target.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Myr Welder

Imprint — {T}: Exile target artifact card from a graveyard.
This creature has all activated abilities of all cards exiled with it.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put this artifact on top of its owner's library.

The One Ring

Indestructible
When The One Ring enters, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Orcus, Prince of Undeath

Flying, trample
When Orcus enters, choose one —
• Each other creature gets -X/-X until end of turn. You lose X life.
• Return up to X target creature cards with total mana value X or less from your graveyard to the battlefield. They gain haste until end of turn.

Sanguine Morass

This land enters tapped.
{T}: Add {B} or {R}.

Bloodsoaked Insight

This spell costs {1} less to cast for each 1 life your opponents have lost this turn.
Target opponent exiles the top three cards of their library. Until the end of your next turn, you may play those cards. If you cast a spell this way, mana of any type can be spent to cast it.